Why it's crucial to prepare men for ART. Demographics and indications for ART.
A total of 9,732 nonidentified donor oocyte ART cycles met criteria for inclusion in this study. Most cycles used oocytes derived from fresh ovarian stimulation cycles (n = 6,943), whereas fewer used frozen oocytes (n = 2,789). The majority of the cycles were performed in men aged 30–39 and 40–49 (<30 years [n = 150], 30–39 years [n = 2,945], 40–49 years [n = 4,902], and ≥50 years [n = 1,735]). The mean age of the oocyte donor (26.3 years in the oldest cohort vs. 26.1 years in the others) did not differ across male age groups (P = .19). However, the frequency of male factor infertility and the distribution of male factor infertility diagnoses did vary significantly by age group. Overall, younger men were more likely than older men to have no male factor infertility diagnoses (<30 years: 88.7%, 30–39 years: 81.4%, 40–49 years: 78.9%, ≥50 years: 77.2%; P<.01). 👇👇👇 #andrologist #maleinfertility #uneuploidembrio #uneuploidy #drruzaev

Although the rates of NOA and severe oligospermia were low in all groups and did not differ significantly by age, rates of moderate oligospermia did increase slightly with age (<30 years: 0.7%, 30–39 years: 2.3%, 40–49 years: 3.2%, ≥50 years 3.3%, P = .03).

Conclusion
This study examined the effect of male age and male factor infertility on embryos biopsied and embryos suitable for transfer, in nonidentified donor oocyte IVF cycles with PGT-A testing. Using a large national database, which included a high number of men in the older age categories, and restricting the analysis to blastocysts, we found no effect of male age on the number of embryos suitable for transfer, and a decrease in the number of embryos suitable for transfer in men with one or more male factor infertility diagnoses. These data suggest that male factor infertility, but not male age, may have a clinically meaningful impact on embryo ploidy.

#andrologist #drruzaev #infertility #infertilitytreatment #euploidy #euploidembrio #unembrio #uneuploidembrio #uneuploid #reproductologist

Преждевременное семяизвержение.
Определение, что считается "за":

Первичная преждевременная эякуляция (ПЭ) на протяжении всей жизни: эякуляция обычно происходит в течение 1 минуты после вагинального проникновения. • Приобретенная (вторичная) ПЭ: клинически значимое сокращение времени задержки, часто определяемое как эякуляция в течение 3 минут. • Критерии DSM-5: определяют преждевременную эякуляцию как эякуляцию, происходящую в течение приблизительно 1 минуты после вагинального проникновения почти во всех или во всех сексуальных контактах. • Сравнение (нормальная задержка): исследования показывают, что среднее время до эякуляции во время вагинального полового акта составляет от 5 до 6 минут.

#андрологрузаев #андролог #кекс #кексолог #андрологсексолог #преждевременноесемяизвержение #семяизвержение #коитус #продолжительностькекса #либидо