Smoking Cessation Intervention for People With Tuberculosis
https://jamanetwork.com/journals/jama/fullarticle/2847305
To the Editor A recent study reported that a tuberculosis (TB)-specific mobile health text-messaging program delivered during TB treatment increased biochemically verified continuous abstinence at 6 months in Bangladesh and Pakistan and was associated with lower mortality. Tobacco cessation during TB care is a major, practical priority, and this trial provides encouraging evidence for scalable support.
https://jamanetwork.com/journals/jama/fullarticle/2847305
To the Editor A recent study reported that a tuberculosis (TB)-specific mobile health text-messaging program delivered during TB treatment increased biochemically verified continuous abstinence at 6 months in Bangladesh and Pakistan and was associated with lower mortality. Tobacco cessation during TB care is a major, practical priority, and this trial provides encouraging evidence for scalable support.
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Burst Exercise Stress Testing in Catecholaminergic Polymorphic Ventricular Tachycardia
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847197
This cohort study evaluates the diagnostic yield and therapeutic impact of the Burst exercise stress testing protocol compared with the traditional Bruce protocol in catecholaminergic polymorphic ventricular tachycardia.
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847197
This cohort study evaluates the diagnostic yield and therapeutic impact of the Burst exercise stress testing protocol compared with the traditional Bruce protocol in catecholaminergic polymorphic ventricular tachycardia.
RBM20 tvs and Human Cardiomyopathy
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847196
This cohort study evaluates the association between RBM20 variants and dilated cardiomyopathy.
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847196
This cohort study evaluates the association between RBM20 variants and dilated cardiomyopathy.
Food Supplementation in Patients Hospitalized for Heart Failure
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847195
This randomized clinical trial evaluates the effect of food supplementation on outcomes following heart failure.
https://jamanetwork.com/journals/jamacardiology/fullarticle/2847195
This randomized clinical trial evaluates the effect of food supplementation on outcomes following heart failure.
Assessing Colorectal Cancer and Mortality Risk in Older Adults
https://jamanetwork.com/journals/jama/fullarticle/2847316
Colonoscopy is one of the most effective cancer prevention interventions developed in the last half-century. The long-term protective effect of colonoscopy has been validated in many well-designed studies. For individuals of screening age, a colonoscopy without adenomas reflects a lower risk of incident and fatal colorectal cancer (CRC) for at least 10 years and potentially up to 20 years.
https://jamanetwork.com/journals/jama/fullarticle/2847316
Colonoscopy is one of the most effective cancer prevention interventions developed in the last half-century. The long-term protective effect of colonoscopy has been validated in many well-designed studies. For individuals of screening age, a colonoscopy without adenomas reflects a lower risk of incident and fatal colorectal cancer (CRC) for at least 10 years and potentially up to 20 years.
Prevention of Respiratory Syncytial Virus–Related Hospitalization in Newborns
https://jamanetwork.com/journals/jama/fullarticle/2847314
To the Editor A recent article compared the real-world effectiveness of the 2 available immunization strategies against respiratory syncytial virus (RSV): passive infant immunization with the long-acting monoclonal antibody nirsevimab vs maternal vaccination with the RSV prefusion F protein (RSVpreF) vaccine. Nirsevimab was associated with lower risk of RSV-related hospitalization, admission to the pediatric intensive care unit, need for ventilatory support, and oxygen treatment. Nonetheless, we believe caution is warranted before drawing conclusions about the superiority of either strategy.
https://jamanetwork.com/journals/jama/fullarticle/2847314
To the Editor A recent article compared the real-world effectiveness of the 2 available immunization strategies against respiratory syncytial virus (RSV): passive infant immunization with the long-acting monoclonal antibody nirsevimab vs maternal vaccination with the RSV prefusion F protein (RSVpreF) vaccine. Nirsevimab was associated with lower risk of RSV-related hospitalization, admission to the pediatric intensive care unit, need for ventilatory support, and oxygen treatment. Nonetheless, we believe caution is warranted before drawing conclusions about the superiority of either strategy.
Prevention of Respiratory Syncytial Virus–Related Hospitalization in Newborns—Reply
https://jamanetwork.com/journals/jama/fullarticle/2847313
In Reply We appreciate the opportunity to respond to comments by Dr Manzoni and colleagues about our study comparing passive infant immunization with nirsevimab and maternal immunization with the RSVpreF vaccine for the prevention of RSV-related hospitalization in newborns.
https://jamanetwork.com/journals/jama/fullarticle/2847313
In Reply We appreciate the opportunity to respond to comments by Dr Manzoni and colleagues about our study comparing passive infant immunization with nirsevimab and maternal immunization with the RSVpreF vaccine for the prevention of RSV-related hospitalization in newborns.
Audio Highlights April 10, 2026
https://jamanetwork.com/journals/jama/fullarticle/2847842
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
https://jamanetwork.com/journals/jama/fullarticle/2847842
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
PCSK9 Inhibitors, GLP-1 Drugs, Shingles Vaccine, and More From ACC 2026
https://jamanetwork.com/journals/jama/fullarticle/2847792
This Medical News article is an interview with Katie Berlacher, MD, MS, an associate professor of medicine at the University of Pittsburgh Medical Center and chair of this year’s American College of Cardiology Scientific Sessions.
https://jamanetwork.com/journals/jama/fullarticle/2847792
This Medical News article is an interview with Katie Berlacher, MD, MS, an associate professor of medicine at the University of Pittsburgh Medical Center and chair of this year’s American College of Cardiology Scientific Sessions.
FDA Approves Once-Daily Psoriasis Pill
https://jamanetwork.com/journals/jama/fullarticle/2847799
The US Food and Drug Administration (FDA) approved icotrokinra, a first-in-class interleukin-23 receptor antagonist for the treatment of moderate to severe plaque psoriasis in patients aged 12 years or older.
https://jamanetwork.com/journals/jama/fullarticle/2847799
The US Food and Drug Administration (FDA) approved icotrokinra, a first-in-class interleukin-23 receptor antagonist for the treatment of moderate to severe plaque psoriasis in patients aged 12 years or older.
ADHD Drug Shortage Cause Identified
https://jamanetwork.com/journals/jama/fullarticle/2847798
The shortage of attention-deficit/hyperactivity disorder (ADHD) medication in the US from 2022-2023 may have been caused by international supply chain disruptions, a study found.
https://jamanetwork.com/journals/jama/fullarticle/2847798
The shortage of attention-deficit/hyperactivity disorder (ADHD) medication in the US from 2022-2023 may have been caused by international supply chain disruptions, a study found.
Hyperkalemia-Induced Sinoventricular Conduction With Wenckebach-Type Block
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2847660
This case report describes a woman in her 30s with a 10-year history of systemic lupus erythematosus presented with fever, chest tightness, oliguria, and lower extremity edema.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2847660
This case report describes a woman in her 30s with a 10-year history of systemic lupus erythematosus presented with fever, chest tightness, oliguria, and lower extremity edema.
Deprescribing Proton Pump Inhibitors and the Challenge of Legacy Medications
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2847659
Less is More
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2847659
Less is More
Beyond Recurrence—Late Effects of Chronic Subdural Hematoma
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847393
In the setting of aging populations and rising antithrombotic use, chronic subdural hematomas (cSDH) are increasingly common in high-income countries. While discussed in the medical literature for centuries, clinical research on cSDH in the modern era initially focused on surgical approaches and the risk of short-term mortality and recurrence. In this setting, cSDH was perceived to be a relatively benign disease; however, recent work has challenged this reputation. Patients with cSDH have persistently elevated long-term mortality when compared with controls, and those who survive are often left with functional and cognitive impairment. Unfortunately, most prior studies of long-term outcomes were small or had limited data on premorbid health, and none had data on functional status or quality of life.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847393
In the setting of aging populations and rising antithrombotic use, chronic subdural hematomas (cSDH) are increasingly common in high-income countries. While discussed in the medical literature for centuries, clinical research on cSDH in the modern era initially focused on surgical approaches and the risk of short-term mortality and recurrence. In this setting, cSDH was perceived to be a relatively benign disease; however, recent work has challenged this reputation. Patients with cSDH have persistently elevated long-term mortality when compared with controls, and those who survive are often left with functional and cognitive impairment. Unfortunately, most prior studies of long-term outcomes were small or had limited data on premorbid health, and none had data on functional status or quality of life.
Cavernous Sinus Dural Arteriovenous Fistula With Ocular Congestion and Proptosis
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847392
This case report describes a 58-year-old man with a 10-day history of left eye redness, proptosis, blurred vision, and left-sided head pressure.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847392
This case report describes a 58-year-old man with a 10-day history of left eye redness, proptosis, blurred vision, and left-sided head pressure.
Long-Term Mortality, Cognition, and Quality of Life After Chronic Subdural Hematoma Surgery
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847391
This population-matched cohort study evaluates long-term survival, excess mortality, and health-related quality of life 10 years after surgical treatment of chronic subdural hematoma.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2847391
This population-matched cohort study evaluates long-term survival, excess mortality, and health-related quality of life 10 years after surgical treatment of chronic subdural hematoma.
2025 Year in Review and Vision for the Path Ahead
https://jamanetwork.com/journals/jama/fullarticle/2847844
In a year defined by rapid change across the clinical, scientific, and public health landscapes, JAMA has maintained a steadfast focus on the integrity of the evidence we publish to inform the care of patients and the health of the public. Throughout 2025, we intensified our efforts to deliver rigorous research and timely perspectives that address pressing challenges to health in the US and across the globe.
https://jamanetwork.com/journals/jama/fullarticle/2847844
In a year defined by rapid change across the clinical, scientific, and public health landscapes, JAMA has maintained a steadfast focus on the integrity of the evidence we publish to inform the care of patients and the health of the public. Throughout 2025, we intensified our efforts to deliver rigorous research and timely perspectives that address pressing challenges to health in the US and across the globe.
The First AI Drug Prescriber
https://jamanetwork.com/journals/jama/fullarticle/2847569
This Viewpoint explores the entry of AI into clinical care, the role of the US Food and Drug Administration, and the associated legal, public health, and medical implications.
https://jamanetwork.com/journals/jama/fullarticle/2847569
This Viewpoint explores the entry of AI into clinical care, the role of the US Food and Drug Administration, and the associated legal, public health, and medical implications.
JAMA Peer Reviewers in 2025
https://jamanetwork.com/journals/jama/fullarticle/2847843
We sincerely thank the 2637 peer reviewers who completed manuscript reviews for JAMA in 2025.
https://jamanetwork.com/journals/jama/fullarticle/2847843
We sincerely thank the 2637 peer reviewers who completed manuscript reviews for JAMA in 2025.
Changes in Mifepristone Use at Pharmacies After Removal of the FDA In-Person Dispensing Requirement
https://jamanetwork.com/journals/jama/fullarticle/2847577
This cross-sectional study examines access to mifepristone through retail and mail-order pharmacies following the US Food and Drug Administration’s (FDA) removal of its in-person dispensing requirement.
https://jamanetwork.com/journals/jama/fullarticle/2847577
This cross-sectional study examines access to mifepristone through retail and mail-order pharmacies following the US Food and Drug Administration’s (FDA) removal of its in-person dispensing requirement.
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