🎙 AITOPIA [NO.2] AI Agents × Biomedicine | Parallel Intelligence Net AMA

This AMA brings together four founders at the frontier of AI Agents × Biomedicine — each running real agentic pipelines already reshaping scientific discovery.

The striking part: all of their systems now run through @Hetu_protocol’s Parallel Intelligence Net — not by partnership, but by convergence. Would like to revise to :Product Management, Medical & Lead Medical Research Team Different teams, different domains, same need: PoCW for verifiable contribution, PoSA for aligned meaning, and Hetu’s dual causal-DAG turning intersubjective consensus into real-time intelligence flow and settlement.

🎤 Speakers
Winnie Qiu — Co-Founder, Avinasi Labs
Walker Chan — CEO, DLife
Fiona — Founder & CEO, GenPulseAI
Elaine — Co-Founder, Genosight
Leonard Andreas Wiyadharma — Product Management, Medical & Lead Medical Research Team, Sally AI

⏰ Time：Dec 5, 19:00–20:00（UTC+8）
🎧 Space Link：https://x.com/i/spaces/1mnxeNXpOXNKX

499 AItopia [EN] No.3: Can an AI Beat T1? A Technical Deep Dive into Training, Latency, and Esports-Grade Inference

Time: Friday, December 5 · 9:00 PM (GMT+8)

If an AI is ever going to challenge T1, it must overcome massive RL training demands, millisecond-level inference, GPU stability, and real-time system constraints.
AItopia No.003 breaks down what it truly takes for AI to reach pro-level esports performance.

🎙 Host: Abhi — Head of Research, Hetu
🎤 Speakers
• Jay Hayter — Content & Community Coordinator, Aethir Cloud
• Kate — Head of Partnerships, io.net

Tune in here:
https://x.com/i/spaces/1yqjd/i/spaces/1YqJDNdgqqOKV
X Community:
http://x.com/i/communities/1987769956122116168
Telegram Group:
http://t.me/+xMlOO3VQH-piZWNl

The Realized No.3: What Kind of Infrastructure Does RWA Actually Need?
Time: Monday, Dec 8th, 2025 9:00 PM (GMT+8)
RWA is moving from narrative to real products, but under every bond, note, or infra yield token sits a more basic question: what kind of chain should all of this actually run on? From Ethereum + L2s to new ‘high-performance’ L1s and RWA-native designs, the trade-offs are only getting sharper.
Hosted by: Suni (@suni_web3) — Committee Member, 499DAO
Featuring: Wish Wu (@wishlonger) — Cofounder and CEO of @pharos_network
Join the Space: https://twitter.com/i/spaces/1RDxlAWVOlqKL
Telegram Group: https://t.me/+xMlOO3VQH-piZWNl
X Community: https://x.com/i/communities/1987769956122116168
We’ll dive into:
RWA is moving from buzzword to actual products, but every bond, note, and infrastructure yield token still sits on top of a messy question: what rails are they really running on? In this talk, we’ll dig into how RWA is becoming an institutional wave, what that means for DeFi users, why chains make very different trade-offs in settlement, risk and market structure, and what an RWA chain actually needs to get right at the base layer.

🎉 499 2026 Offline Event Roadmap Officially Released

In 2026, 499 will launch a series of offline summits and industry gatherings across key Web3 cities worldwide, covering major events such as Consensus HK, ETHDenver, ETHCC, TOKEN2049 Dubai & Singapore, KBW Seoul, and more.

This global tour will bring together top projects and builders, leading investors and financial institutions, as well as Web2 × Web3 × AI ecosystem partners, focusing on in-depth discussions and high-quality connections around RWA, DeAI, AI × Ethereum, and real-world Web3 adoption with global market integration. Each stop will not only be a content-rich summit but also a high-density, actionable ecosystem connection hub.

👉 For sponsorships, co-hosting, or ecosystem collaboration, reach out to the 499 team and join us in shaping the key narratives of Web3 in 2026.

Consensus HK 2026 Update: Ticket Prices Have Increased! 📈

499 is proud to be an Official Community Partner for Consensus Hong Kong (Feb 10–12, 2026)! 🇭🇰

With a stellar lineup including Binance, Solana, J.P. Morgan, and TRON, and 15,000+ attendees expected, this is the premier event of the year.

⚠️ Price Update: Please note that ticket prices increased on Jan 16. If you haven't secured your pass yet, don't wait any longer! You can still save up to $1,000 off the walk-up rate by using our community code today.

🎟 Community Code: 0X499DESK
👉 Register Now: go.coindesk.com/hk26-0x499

#Consensus2026 #0x499 #Crypto #Web3 #HongKong

Proof of AI - Builder & Influencer Night

Co-hosted by 499, Kite AI and PayPal Ventures, this exclusive AI × Web3 party is landing in Hong Kong and Denver this February 2026!
Focused on Stablecoin, Agentic Payment, and Autonomous Economy, it links core industry resources to redefine Web3 innovation dialogues.

What to Expect
- Deep Dives: Explore frontier trends of the three core tracks with industry pioneers
- Targeted Connections: Forge face-to-face ties with AI x blockchain builders, VCs, institutional partners, and cross-track innovators
- Relaxed Networking: Light bites, premium drinks, and actionable conversations — no surface-level small talk

Stand with the builders shaping the decentralized future and unlock the next industry wave!

Event Details & RSVP
- Hong Kong (during ConsensusHK)
Sign up: https://luma.com/ProofofAIHK

- Denver (during EthDenver)
Sign up: https://luma.com/ProofofAIDenver

The Scaling Summit @ ETHDenver 2026

During ETHDenver 2026, 499 partners with 0G to co-host The Scaling Summit — a high-signal, invite-focused gathering for builders, founders, and ecosystem leaders working at the intersection of AI, Web3, and next-generation infrastructure.

0G is the largest ecosystem of decentralized AI applications, combines multiple specialized, interconnected technologies built for real-world AI workloads at scale.

What to expect
* Curated discussions with deeper panels and deeper conversations
* Strong North American builder presence with global perspectives
* A highly focused audience of teams actively shipping and scaling

If you are exploring AI infrastructure, decentralized AI (DeAI), agent networks, or the evolution of scaling beyond today’s narratives, this is a must-attend ETHDenver side event.

Registration: https://luma.com/ScalingEthDenver