New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged. Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to organisms'…

We studied the genomes of African and Asian leopards using specimens from natural history museums.

Two researchers explain the importance of rigorously designed studies

A new Netflix drama explores this idea - but could it work in real life?

Genetically modifying mosquitoes to express antimalarial genes and pass them on to their offspring is being tested as a new strategy to eliminate malaria. Altering a mosquito’s gut genes to make them spread antimalarial genes to the next generation of their…

Trillions of viruses were injected into the brain of Benny Landsman in a bid to treat a rare nerve disease.

Rhinoviruses, which cause the common cold, can limit the replication of the coronavirus responsible for Covid19.

While cannabis users reported more psychotic experiences than non-users generally, the effect was more pronounced in those with a genetic risk factor for schizophrenia.

A new gene editing technology called CRISPRoff allows researchers to control gene expression with high specificity while leaving the sequence of the DNA unchanged.

An enzyme called AMPK drives the clearance of damaged mitochondria, each cell's energy source, by rapidly promoting the initial activation of the parkin protein — whose deficiency is linked to...

Mechanism discovered for the degradation of key cell-cycle regulators.

Global health body warns none of antibiotics currently being developed are enough to tackle superbugs

The first full human genome was sequenced 20 years ago. Now, a project is underway to sequence 1 million genomes to better understand the complex relationship between genetics, diversity and disease.

Where ancient humans lived — and when — can be unveiled using DNA extracted from sediment layers dug from cave floors.

Estatuas cave in northern Spain was a hive of activity 105,000 years ago. Artifacts show its Neanderthal inhabitants hafted stone tools, butchered red deer, and may have made fires. They also shed, bled, and excreted subtler clues onto the cave floor: their…

It is an old-standing theory in evolutionary ecology: animal species on islands have the tendency to become either giants or dwarfs in comparison to mainland relatives. Since its formulation in the 1960s, however, the 'island rule' has been severely debated…