NOTES NEXT DOOR (Official)
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#Dvtupdate

Hello doctor's
Slot 1 has been successfully dispatched .
Tracking ids will be updated within 24 hrs.

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Team NND ❤️
EXPLANATION:
Inflammation involving an epithelial surface may
cause such extensive necrosis that the surface becomes
eroded, forming an ulcer. If the inflammation continues,
the ulecer can continue to penetrate downward into submu-
cosa and muscularis. Alternatively, the ulcer may heal, or it
may remain chronically inflamed. An abscess is a localized
collection of neutrophils in tissues. A caseating granuloma
is granulomatous inflammation with central necrosis; the
necrosis has elements of both liquefaction and coagula-
tive necrosis. Chronic inflammation occurs when there is
a preponderance of mononuclear cells, such as lympho-
cytes, macrophages, and plasma cells, in a process that has
gone on for more than a few days—more likely weeks or
months—or that accompanies repeated bouts of acute in-
flammation. Pus, or a purulent exudate, appears semiliquid
and yellowish because of the large numbers of granulocytes
present. A serous effusion is a watery-appearing transudate
that resembles an ultrafiltrate of blood plasma, with a low
cell and protein content
#Dvtupdate

Hello Doctors
Most of the tracking ids have been updated successfully. Kindly kill your app and check your order section. We are still updating tracking ids, those who have not received the dispatch notification with tracking id will receive soon within 24 hrs.

All students from slot 1 will receive DVT notes in 2 packets .
This is done to avoid damage to the notes .
If you receive one packet early don't panic you will receive other one too.

#softcopyupdate
Rest softcopies will be updated within 24 hrs.
We are updating in parts because the files are very heavy and if we upload whole file at once it would be very difficult for most of the students to open since it will take alot of time.

Regards
Team NND ❤️
NOTES NEXT DOOR (Official) pinned «#Dvtupdate Hello Doctors Most of the tracking ids have been updated successfully. Kindly kill your app and check your order section. We are still updating tracking ids, those who have not received the dispatch notification with tracking id will receive soon…»
Multiple members of a family have a disease that is as-
sociated with a genetic change that involves substitution of
adenine for thymine involving one base pair on homologous chromosomes. What is the best term to describe this finding
Anonymous Quiz
4%
Copy number variation
6%
Deletion
23%
Epigenetic change
67%
Single nucleotide polymorphism
EXPLANATION:
Single nucleotide polymorphisms (SNPs) are found
in less than 0.5% of the genome, and only 1% of these are
found in coding regions that affect protein synthesis. Some
of these account for point mutations that may be associated
with disease conditions. C number variations (CNVs) in-
volve variations in large contiguous regions of DNA from
1000 to a million base pairs. Epigenetic changes involve
modulation of gene expression without any change in the
DNA. Trinucleotide repeats involve increased numbers of
base pairs. RNA alterations may modulate DNA expres-
sion, such as noncoding micro RNAs.
Guys vol 2 is taking alot of time to print this might cause delay in shipping, Since exams are nearing shall we provide some content from vol 2 in pdf form via Google drive so that it will save time and we can start Shipping early. ?
Anonymous Quiz
61%
Yes
31%
No
9%
Maybe
NOTES NEXT DOOR (Official) pinned «Guys vol 2 is taking alot of time to print this might cause delay in shipping, Since exams are nearing shall we provide some content from vol 2 in pdf form via Google drive so that it will save time and we can start Shipping early. ?»
study of peripheral blood smears shows that neutrophil nuclei of women have a Barr body whereas those of men
do not.The Barr body is an inactivated X chromosome.Which
of the following forms of RNA is most likely to play a role in Barr body formation
Anonymous Quiz
27%
IncRNA
26%
mRNA
29%
miRNA
18%
siRNA
Explanation:
There are forms of noncoding RNA that play a role in
gene expression. Long noncoding RNA (lncRNA) segments
greater than 200 nucleotides in length can bind to chroma-
tin to restrict access of RNA polymerase to coding segments.
The X chromosome transcribes XIST, a lncRNA that binds to
and represses X chromosome expression. However, not all
genes on the “inactive” X chromosome are switched off. The
RNA transcribed from nuclear DNA that directs protein syn-
thesis through translation is mRNA. MicroRNAs (miRNAs)
are noncoding RNA sequences that inhibit the translation
of mRNAs. Gene-silencing RNAs (small interfering RNAs
[siRNAs]) have the same function as miRNAs, but they are
produced synthetically for experimental purposes. Transfer
RNA (tRNA) participates in the translation of mRNA to pro-
teins by linking to specific amino acids.
#Dvtupdate

Hello doctor's
We respect point of view of all individuals.

Some of you have misinterpreted our yesterday's poll.
We'll be providing Hardcopies of both volumes but we'll be providing pdf of some content (only infectious disease ) for free that won't be included in hardcopy.

1st slot vol 2 has been shipped already.

Those who have paid 100 extra for early shipping of vol 1,Their vol 1 has been shipped .

We have updated the tracking ids of most of the order's kindly check your my order section. However still some tracking ids have been not updated since they have been shipped via different courier services.
We'll update them soon.

We'll start shipping vol 1 & vol 2 from 6th onwards for 2nd and 3rd slot.

Stay safe

Regards
Team NND ❤️
NOTES NEXT DOOR (Official) pinned «#Dvtupdate Hello doctor's We respect point of view of all individuals. Some of you have misinterpreted our yesterday's poll. We'll be providing Hardcopies of both volumes but we'll be providing pdf of some content (only infectious disease ) for free…»
11-year-old child falls and cuts his hand. The wound
becomes infected. Bacteria extend into the extracellular matrix
around capillaries. In the inflammatory response to this infec- tion, which of the following cells removes the bacteria?
Anonymous Quiz
7%
B Lymphocytes
9%
Mast cells
74%
Macrophages
9%
T lymphocytes
Explanation:-
Macrophages in tissues derived from circulating
blood monocytes are phagocytic cells that respond to a va-
riety of stimuli, and they represent the janitorial crew of the
body. The other cells listed are not phagocytes. B cells can
differentiate into plasma cells secreting antibodies to neutral-
ize infectious agents. Fibroblasts form collagen as part of a
healing response. Mast cells can release a variety of inflam-
matory mediators. T cells are a key part of chronic inflamma-
tory processes in cell-mediated immune responses.
#NNDVT_UPDATE

Hello doctors
We are getting a lot of queries from Hardcopy buyers that they are unable to access the pdf on app.
To solve this we are going to make the softcopy subscription free for half an hour.
You can subscribe to the product and start accessing on app itself.

Note : subscription will be free for half an hour only.
No queries of hardcopy buyers will be entertained after half an hour regarding unable to access softcopy.
No pdf free access will be provided to new Hardcopy buyers .

Regards
Team NND ❤️
NOTES NEXT DOOR (Official) pinned «#NNDVT_UPDATE Hello doctors We are getting a lot of queries from Hardcopy buyers that they are unable to access the pdf on app. To solve this we are going to make the softcopy subscription free for half an hour. You can subscribe to the product and start…»
40-year-old man has a positive stool guaiac test during a routine physical examination.A colonoscopy
isperformed and a 0.9-cm, circumscribed,pedunculated mass ona short stalk is found in the upperrectum.Term this lesion?
Anonymous Quiz
46%
Adenoma
33%
Choristoma
17%
Carcinoma
4%
Sarcoma
Explanation:-
A discrete small mass such as that described is proba-
bly benign. Adenomas arise from epithelial surfaces. Though
adenocarcinoma may arise from a colonic adenoma, such ma-
lignant lesions tend to be larger and more irregular. A choris-
toma is a benign mass composed of tissues not found at the
site of origin. A hamartoma is a rare benign mass composed
of tissues usually found at the site of origin. A hyperplastic
colonic lesion tends to be smaller and flatter. A sarcoma is a
malignant neoplasm arising in mesenchymal tissues, not in
epithelium