NOTES NEXT DOOR (Official)
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Explanation:-
Growth factor release from activated platelets, mac-
rophages, and vascular wall cells induces smooth muscle cell
recruitment, medial smooth muscle migrate into the intima,
proliferate, and synthesize extracellular matrix (ECM) in much
the same way that fibroblasts fill in a wound. Endothelial cell
injury initiates atherogenesis, but endothelial cells do not form
a significant part of an atheroma. Platelets do not synthesize
ECM. T cells secrete inflammatory cytokines that activate mac-
rophages, endothelial cells, and smooth muscle cells.
NOTES NEXT DOOR (Official) pinned Β«A study of atheromatous plaques shows that release of growth factors, including PDGF, FGF, and TNF-Ξ± leads to increased extracellular matrix production.result, the size of the plaques increases. Which cells will release growth factors in the plaques?Β»
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Forwarded from ARTI Agrawal
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Property of elution is found in
Anonymous Quiz
33%
Myxovirus
26%
Togavirus
16%
Panovirus
24%
Adenovirus
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Pathogenicity of staphylococcus is because of
Anonymous Quiz
13%
Lecithinase
41%
Coagulase
36%
M protien
10%
Cell wall
In Human sera,kappa and lambda chain occur in ratio of
Anonymous Quiz
20%
1:2
19%
1:1
44%
2:1
17%
4:1
Forwarded from Akshitha
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Graft vs host reactions is caused by
Anonymous Quiz
19%
B lymphocytes
62%
T lymphocytes
9%
Macrophages
10%
Complement
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Example of an artificial virus
Anonymous Quiz
51%
Vaccinia virus
8%
Rabies virus
4%
Mumps virus
38%
Reo virus
Anton test is used in the diagnosis of
Anonymous Quiz
23%
Diptheria
18%
H influenza
54%
L monocytogenes
5%
S pneumoniae
In a clinical study patients diagnosed with carcinoma whose tumor stage is T4N1M1.The patients survival rate 5 years from the time of diagnosis is less than 50%,regardless of therapy.Which of the clinical findings likely to be characteristic of patient?
Anonymous Quiz
63%
Cachexia
18%
Cardiac murmur
9%
Icterus
9%
Splenomegaly
Explanation:-
Cachexia is a common finding in advanced cancers,
and weight loss without dieting in an adult is a β€œred flag”
for malignancy. The exact cause for this is unknown, but
increases in circulating factors such as tumor necrosis fac-
tor (TNF) may play a role. Cardiac murmurs may occur in
the development of nonbacterial thrombotic endocarditis, a
feature of a hypercoagulable state that may occur with ad-
vanced malignancies. Icterus is most likely to occur when
there is obstruction of the biliary tract by a mass (e.g., as in
pancreatic cancer), but metastases are unlikely to cause such
an obstruction. Neurologic abnormalities may occur in lo-
cal tumor growth impinging on nerves, but dull constant
pain is the most likely abnormality in malignant neoplasms
that invade nerves. Metastases to the spleen are uncommon.
Tympany is uncommon in cancer because obstruction by a
mass tends to be incomplete and to develop over a long time.
(Hint: an empty beer keg is tympanitic when percussed.)
Staphylococcal toxic syndrome is due to
Anonymous Quiz
39%
Enterotoxin A
20%
Enterotoxin D
26%
Enterotoxin E
15%
Enterotoxin F