β€1
π Sowa-Rigpa & Bhoti-Language Manuscripts
π Why in News?
β Ayush Minister Prataprao Jadhav called for global recognition of Sowa-Rigpa as an evidence-based system of medicine
β He also emphasised preservation of ancient Bhoti-language manuscripts containing valuable knowledge of Sowa-Rigpa
π About Sowa-Rigpa
π What is it?
β Sowa-Rigpa is one of the worldβs oldest traditional systems of medicine
β Also known as the Amchi System and Tibetan Medicine
β The term Sowa-Rigpa means βKnowledge of Healingβ and originates from the Bhoti language
β Buddha is traditionally regarded as the originator of this system
π Geographical Spread
β Developed and strengthened in the Trans-Himalayan region
β Practised in Ladakh, Himachal Pradesh, Jammu & Kashmir, Sikkim, Arunachal Pradesh, and Darjeeling
β Also practised in parts of China, Nepal, Bhutan, Mongolia, and Russia
π Key Features
β More than 75% of its texts are derived from Ashtanga Hridaya, an important classical text of Ayurveda
β Uses several Indian medicinal plants and formulations, including Ashwagandha, Guggulu, Triphala, Ashoka, and Haridra
β Gyud-Zi (Four Tantras) is the fundamental textbook of Sowa-Rigpa
β Recognised under Indiaβs Ayush framework
β Represents an important repository of Trans-Himalayan traditional medical knowledge
π National Institute of Sowa-Rigpa
β National Institute of Sowa-Rigpa is Indiaβs apex institution for education, research, and healthcare in the Sowa-Rigpa system
π Bhoti-Language Manuscripts
π What are they?
β Historical, religious, and medical texts written in the traditional Bhoti script
β Bhoti script is derived from the Tibetan script
β Traditionally used extensively in Buddhist monasteries for religious teachings and scriptures
β Some manuscripts preserve centuries-old knowledge of Sowa-Rigpa
π Significance
β Preservation of Bhoti manuscripts can help safeguard traditional medical knowledge and cultural heritage
β Scientific study and documentation can support the evidence-based validation of traditional practices
β Recognition of Sowa-Rigpa can strengthen Indiaβs traditional medicine diplomacy and cultural heritage
β Protecting manuscripts is important for preventing the loss of indigenous knowledge passed through generations
π Prelims Facts
β Sowa-Rigpa β βKnowledge of Healingβ
β Also known as β Amchi / Tibetan Medicine
β Core text β Gyud-Zi (Four Tantras)
β Major influence β Ashtanga Hridaya
β Region β Trans-Himalayan region
β Bhoti script β Derived from Tibetan script
β National Institute of Sowa-Rigpa β Indiaβs apex institution for education, research and healthcare in Sowa-Rigpa
#prelims
#art_and_culture
https://t.me/Studytoday1
https://t.me/upsc_art_and_culture
π Why in News?
β Ayush Minister Prataprao Jadhav called for global recognition of Sowa-Rigpa as an evidence-based system of medicine
β He also emphasised preservation of ancient Bhoti-language manuscripts containing valuable knowledge of Sowa-Rigpa
π About Sowa-Rigpa
π What is it?
β Sowa-Rigpa is one of the worldβs oldest traditional systems of medicine
β Also known as the Amchi System and Tibetan Medicine
β The term Sowa-Rigpa means βKnowledge of Healingβ and originates from the Bhoti language
β Buddha is traditionally regarded as the originator of this system
π Geographical Spread
β Developed and strengthened in the Trans-Himalayan region
β Practised in Ladakh, Himachal Pradesh, Jammu & Kashmir, Sikkim, Arunachal Pradesh, and Darjeeling
β Also practised in parts of China, Nepal, Bhutan, Mongolia, and Russia
π Key Features
β More than 75% of its texts are derived from Ashtanga Hridaya, an important classical text of Ayurveda
β Uses several Indian medicinal plants and formulations, including Ashwagandha, Guggulu, Triphala, Ashoka, and Haridra
β Gyud-Zi (Four Tantras) is the fundamental textbook of Sowa-Rigpa
β Recognised under Indiaβs Ayush framework
β Represents an important repository of Trans-Himalayan traditional medical knowledge
π National Institute of Sowa-Rigpa
β National Institute of Sowa-Rigpa is Indiaβs apex institution for education, research, and healthcare in the Sowa-Rigpa system
π Bhoti-Language Manuscripts
π What are they?
β Historical, religious, and medical texts written in the traditional Bhoti script
β Bhoti script is derived from the Tibetan script
β Traditionally used extensively in Buddhist monasteries for religious teachings and scriptures
β Some manuscripts preserve centuries-old knowledge of Sowa-Rigpa
π Significance
β Preservation of Bhoti manuscripts can help safeguard traditional medical knowledge and cultural heritage
β Scientific study and documentation can support the evidence-based validation of traditional practices
β Recognition of Sowa-Rigpa can strengthen Indiaβs traditional medicine diplomacy and cultural heritage
β Protecting manuscripts is important for preventing the loss of indigenous knowledge passed through generations
π Prelims Facts
β Sowa-Rigpa β βKnowledge of Healingβ
β Also known as β Amchi / Tibetan Medicine
β Core text β Gyud-Zi (Four Tantras)
β Major influence β Ashtanga Hridaya
β Region β Trans-Himalayan region
β Bhoti script β Derived from Tibetan script
β National Institute of Sowa-Rigpa β Indiaβs apex institution for education, research and healthcare in Sowa-Rigpa
#prelims
#art_and_culture
https://t.me/Studytoday1
https://t.me/upsc_art_and_culture
π3β€2
#Goodmorning 4am club
β³10 days left CSM26 [ 21-08-26]
β³285 days left CSP27 [ 23-05-27]
β³374 days left CSM27 [ 20-08-27]
β³117 days left UPPSC/RAS prelims 6 December
β³34 Day left CDS/NDA 2 13 Sept
β³28 day left Mppsc mains26 7 September
#Target
#TargetOnlyone
#Accountability
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β³10 days left CSM26 [ 21-08-26]
β³285 days left CSP27 [ 23-05-27]
β³374 days left CSM27 [ 20-08-27]
β³117 days left UPPSC/RAS prelims 6 December
β³34 Day left CDS/NDA 2 13 Sept
β³28 day left Mppsc mains26 7 September
#Target
#TargetOnlyone
#Accountability
https://t.me/anmolvachan1
β€5
π CURRENT AFFAIRS β 10 AUGUST 2026
π GEOGRAPHY
π Mising Community β Assam
β Mising is Assamβs second-largest plains tribe
β Known for adapting to the seasonal floods of the Brahmaputra River
β Chang Ghar: Bamboo-and-wood houses built on raised platforms; can be rebuilt after severe floods
β Agricultural cycles are aligned with the riverβs natural ebb and flow
β Sustainable fishing practices are used during the monsoon
β Ali-Aye-Ligang festival, animist traditions and handloom practices reflect their cultural ecology
β Boro/Bodo is Assamβs largest plains tribe
π POLITY & GOVERNANCE
π 13th BRICS Education Ministersβ Meeting
β Held in Bhubaneswar, Odisha
β Hosted by the Ministry of Education under Indiaβs BRICS Chairship 2026
β Theme: βBuilding for Resilience, Innovation, Cooperation, and Sustainabilityβ
β Focus: ECCE, skill development, research & innovation, mutual recognition of qualifications and academic leadership
β Members adopted the 13th BRICS Education Ministersβ Declaration
β BRICS Network University to incorporate traditional and indigenous knowledge as a new International Thematic Group
π E-Samudra Platform
β Launched by the Ministry of Ports, Shipping and Waterways (MoPSW)
β Developed with technology partner CMS Computers India Ltd.
β Aim: shift maritime administration towards Digital First and Faceless Governance
β Provides a single digital window for ports, shipping companies and seafarers
β Enables paperless transactions, online payments and real-time request tracking
β Generates tamper-proof digital certificates
β e-NAVIK: 24Γ7 seafarer grievance-redressal portal
β d-SEA: Digital Seafarers Employment Agreement
β Includes vessel and seafarer-related digital modules
π Caste Enumeration in Census 2027
β Ladakh is set to lead Independent Indiaβs first comprehensive caste enumeration
β First comprehensive caste-wise enumeration since the 1931 Census
β Census 2027 will be Indiaβs first digital census
β Ladakh will primarily use paper schedules due to security concerns near sensitive border areas
β 2011 SECC was an independent survey and did not have statutory backing under the Census Act, 1948
β Its caste data was not publicly released due to data-quality concerns
β Census 2027 will have an open-ended caste column
π ECONOMY
π India Crosses 300 GW Non-Fossil Fuel Capacity
β India crossed 300 GW of installed non-fossil fuel electricity capacity
β Capacity reached 300.50 GW in 2026
β Accounts for over 54% of total installed electricity capacity
β Total electricity capacity: around 552 GW
β Solar: 164.59 GW
β Wind: 58.14 GW
β Hydropower: 57.24 GW
β Bio-power: 11.75 GW
β Nuclear: 8.78 GW
π AGRICULTURE
π Mithila Makhana Exported to Australia
β First-ever export of GI-tagged Mithila Makhana from Bihar to Australia
β Received GI tag in 2022
β Originates from the Mithila region of Bihar
β Mithila accounts for nearly 85% of Indiaβs Makhana cultivation
β Also known as fox nut/gorgon nut
β Rich in plant-based protein, calcium, magnesium and antioxidants
β Low in cholesterol and fat
π ENVIRONMENT
π Fishermen-led Invasive Species Removal β Ujani Reservoir
β Indiaβs first fishermen-driven removal initiative launched at Ujani Reservoir, Maharashtra
β Launched by Bombay Natural History Society (BNHS)
β Reservoir lies on the Bhima River
β Targets invasive suckermouth catfish
β Local fishers are incentivised to capture and remove the invasive fish
β Combines biodiversity conservation with livelihood support
π Striped Hyena
β A 2026 study highlighted limited public understanding of the striped hyenaβs secretive lifestyle
β Study conducted by HEAL and NCBS
β Scientific name: Hyaena hyaena
β Solitary and primarily nocturnal scavenger
β Found across parts of Africa, the Middle East, Central Asia and the Indian subcontinent
β Only living species in the genus Hyaena
β IUCN status: Near Threatened
β Global population: fewer than 10,000 mature individuals, according to the provided source
#CurrentAffairs
π GEOGRAPHY
π Mising Community β Assam
β Mising is Assamβs second-largest plains tribe
β Known for adapting to the seasonal floods of the Brahmaputra River
β Chang Ghar: Bamboo-and-wood houses built on raised platforms; can be rebuilt after severe floods
β Agricultural cycles are aligned with the riverβs natural ebb and flow
β Sustainable fishing practices are used during the monsoon
β Ali-Aye-Ligang festival, animist traditions and handloom practices reflect their cultural ecology
β Boro/Bodo is Assamβs largest plains tribe
π POLITY & GOVERNANCE
π 13th BRICS Education Ministersβ Meeting
β Held in Bhubaneswar, Odisha
β Hosted by the Ministry of Education under Indiaβs BRICS Chairship 2026
β Theme: βBuilding for Resilience, Innovation, Cooperation, and Sustainabilityβ
β Focus: ECCE, skill development, research & innovation, mutual recognition of qualifications and academic leadership
β Members adopted the 13th BRICS Education Ministersβ Declaration
β BRICS Network University to incorporate traditional and indigenous knowledge as a new International Thematic Group
π E-Samudra Platform
β Launched by the Ministry of Ports, Shipping and Waterways (MoPSW)
β Developed with technology partner CMS Computers India Ltd.
β Aim: shift maritime administration towards Digital First and Faceless Governance
β Provides a single digital window for ports, shipping companies and seafarers
β Enables paperless transactions, online payments and real-time request tracking
β Generates tamper-proof digital certificates
β e-NAVIK: 24Γ7 seafarer grievance-redressal portal
β d-SEA: Digital Seafarers Employment Agreement
β Includes vessel and seafarer-related digital modules
π Caste Enumeration in Census 2027
β Ladakh is set to lead Independent Indiaβs first comprehensive caste enumeration
β First comprehensive caste-wise enumeration since the 1931 Census
β Census 2027 will be Indiaβs first digital census
β Ladakh will primarily use paper schedules due to security concerns near sensitive border areas
β 2011 SECC was an independent survey and did not have statutory backing under the Census Act, 1948
β Its caste data was not publicly released due to data-quality concerns
β Census 2027 will have an open-ended caste column
π ECONOMY
π India Crosses 300 GW Non-Fossil Fuel Capacity
β India crossed 300 GW of installed non-fossil fuel electricity capacity
β Capacity reached 300.50 GW in 2026
β Accounts for over 54% of total installed electricity capacity
β Total electricity capacity: around 552 GW
β Solar: 164.59 GW
β Wind: 58.14 GW
β Hydropower: 57.24 GW
β Bio-power: 11.75 GW
β Nuclear: 8.78 GW
π AGRICULTURE
π Mithila Makhana Exported to Australia
β First-ever export of GI-tagged Mithila Makhana from Bihar to Australia
β Received GI tag in 2022
β Originates from the Mithila region of Bihar
β Mithila accounts for nearly 85% of Indiaβs Makhana cultivation
β Also known as fox nut/gorgon nut
β Rich in plant-based protein, calcium, magnesium and antioxidants
β Low in cholesterol and fat
π ENVIRONMENT
π Fishermen-led Invasive Species Removal β Ujani Reservoir
β Indiaβs first fishermen-driven removal initiative launched at Ujani Reservoir, Maharashtra
β Launched by Bombay Natural History Society (BNHS)
β Reservoir lies on the Bhima River
β Targets invasive suckermouth catfish
β Local fishers are incentivised to capture and remove the invasive fish
β Combines biodiversity conservation with livelihood support
π Striped Hyena
β A 2026 study highlighted limited public understanding of the striped hyenaβs secretive lifestyle
β Study conducted by HEAL and NCBS
β Scientific name: Hyaena hyaena
β Solitary and primarily nocturnal scavenger
β Found across parts of Africa, the Middle East, Central Asia and the Indian subcontinent
β Only living species in the genus Hyaena
β IUCN status: Near Threatened
β Global population: fewer than 10,000 mature individuals, according to the provided source
#CurrentAffairs
β€6
π SCIENCE & TECHNOLOGY
π EVEREST Rocket Engine
β Developed by Astrobase Space Technologies
β Claimed as Indiaβs first privately built 800 kN Full-Flow Staged Combustion (FFSC) engine
β Propellants: Liquid Oxygen (LOX) + Liquid Methane
β Thrust: 800 kN
β Specific impulse: 340 seconds
β Throttle range: 50β110%
β Designed for reusable medium-lift launch vehicles
β FFSC capability places India alongside Russia, USA and China, according to the source
π IMPORTANT DAYS
π International Day of the Worldβs Indigenous Peoples
β Observed annually on 9 August
β Established by the UN General Assembly in 1994
β Commemorates the first meeting of the UN Working Group on Indigenous Populations in 1982
β Aim: promote and protect the rights of Indigenous peoples
β 2026 Theme: βHonouring Indigenous Midwives: Safeguarding Life and Well-beingβ
#CurrentAffairs
π EVEREST Rocket Engine
β Developed by Astrobase Space Technologies
β Claimed as Indiaβs first privately built 800 kN Full-Flow Staged Combustion (FFSC) engine
β Propellants: Liquid Oxygen (LOX) + Liquid Methane
β Thrust: 800 kN
β Specific impulse: 340 seconds
β Throttle range: 50β110%
β Designed for reusable medium-lift launch vehicles
β FFSC capability places India alongside Russia, USA and China, according to the source
π IMPORTANT DAYS
π International Day of the Worldβs Indigenous Peoples
β Observed annually on 9 August
β Established by the UN General Assembly in 1994
β Commemorates the first meeting of the UN Working Group on Indigenous Populations in 1982
β Aim: promote and protect the rights of Indigenous peoples
β 2026 Theme: βHonouring Indigenous Midwives: Safeguarding Life and Well-beingβ
#CurrentAffairs
β€2
Fundamental Rights 1 page's Short Notes
10 page just 30 sec
https://www.instagram.com/reel/Db4jsWsIXKW/
10 page just 30 sec
https://www.instagram.com/reel/Db4jsWsIXKW/
π2
π Suo Motu Cognisance and the Limits of Judicial Intervention
π Why in Focus?
β The increasing use of suo motu cognisance by the Supreme Court of India has sparked debate over judicial activism, separation of powers, and the role of lower courts.
π What is Suo Motu Cognisance?
β Suo motu means βon its own motionβ.
β Empowers the Supreme Court and High Courts to initiate proceedings without a formal petition.
β Derived from the broad constitutional powers under Article 32 and Article 142.
β Evolved through the expansion of Public Interest Litigation (PIL) jurisprudence.
π Purpose
β Protect fundamental rights when affected persons cannot approach courts.
β Address grave injustices and constitutional violations.
β Respond to state inaction or systemic failures.
β Act as a constitutional safeguard in exceptional situations.
π Rise in Suo Motu Cases
β Increasingly used as an active judicial tool rather than a rare residual power.
β The Supreme Court registered more suo motu cases during 2020β24 than in the preceding fifteen years.
β Indicates growing judicial intervention in matters of public concern.
π Benefits of Suo Motu Jurisdiction
β Provides quick judicial response during emergencies.
β Protects vulnerable and marginalized groups.
β Ensures accountability of public authorities.
β Addresses issues involving human rights, governance failures, and environmental concerns.
β Strengthens public confidence in constitutional institutions.
π Concerns and Challenges
β Judicial Overreach: May blur the boundaries between judiciary, executive, and legislature.
β Media-Driven Intervention: High-profile cases receiving extensive media coverage often attract judicial attention.
β Bypassing Lower Courts: Frequent intervention may undermine confidence in subordinate courts.
β Selective Attention: Thousands of serious cases remain unheard while a few receive extraordinary monitoring.
β Institutional Burden: Diverts judicial resources from broader structural reforms.
π Need for Institutional Balance
β Respect the principle of Separation of Powers.
β Follow the principle of Subsidiarity, allowing lower courts and High Courts to address local matters first.
β Use suo motu powers primarily for systemic failures and constitutional crises.
β Strengthen trial courts through better infrastructure, staffing, and training.
β Establish objective guidelines for initiating suo motu proceedings.
π Way Forward
β Formulate transparent criteria for exercising suo motu jurisdiction.
β Focus on long-term judicial reforms rather than case-specific monitoring.
β Fill judicial vacancies and modernize court administration.
β Enhance coordination between the Supreme Court, High Courts, and subordinate judiciary.
β Preserve the exceptional nature of suo motu intervention.
π Significance
β Suo motu cognisance remains a powerful constitutional tool for protecting justice.
β However, excessive reliance may create perceptions of judicial paternalism and institutional overreach.
β A balance between judicial activism and judicial restraint is essential for maintaining constitutional governance.
π UPSC Relevance
β Prelims: Article 32, Article 142, PIL, Suo Motu Cognisance.
β Mains (GS2): Judiciary, Judicial Activism, Separation of Powers, Constitutional Governance, Judicial Reforms.
β Essay: Judicial Activism vs Judicial Restraint; Role of Judiciary in Democracy.
#GS2 #Polity #mains
π Why in Focus?
β The increasing use of suo motu cognisance by the Supreme Court of India has sparked debate over judicial activism, separation of powers, and the role of lower courts.
π What is Suo Motu Cognisance?
β Suo motu means βon its own motionβ.
β Empowers the Supreme Court and High Courts to initiate proceedings without a formal petition.
β Derived from the broad constitutional powers under Article 32 and Article 142.
β Evolved through the expansion of Public Interest Litigation (PIL) jurisprudence.
π Purpose
β Protect fundamental rights when affected persons cannot approach courts.
β Address grave injustices and constitutional violations.
β Respond to state inaction or systemic failures.
β Act as a constitutional safeguard in exceptional situations.
π Rise in Suo Motu Cases
β Increasingly used as an active judicial tool rather than a rare residual power.
β The Supreme Court registered more suo motu cases during 2020β24 than in the preceding fifteen years.
β Indicates growing judicial intervention in matters of public concern.
π Benefits of Suo Motu Jurisdiction
β Provides quick judicial response during emergencies.
β Protects vulnerable and marginalized groups.
β Ensures accountability of public authorities.
β Addresses issues involving human rights, governance failures, and environmental concerns.
β Strengthens public confidence in constitutional institutions.
π Concerns and Challenges
β Judicial Overreach: May blur the boundaries between judiciary, executive, and legislature.
β Media-Driven Intervention: High-profile cases receiving extensive media coverage often attract judicial attention.
β Bypassing Lower Courts: Frequent intervention may undermine confidence in subordinate courts.
β Selective Attention: Thousands of serious cases remain unheard while a few receive extraordinary monitoring.
β Institutional Burden: Diverts judicial resources from broader structural reforms.
π Need for Institutional Balance
β Respect the principle of Separation of Powers.
β Follow the principle of Subsidiarity, allowing lower courts and High Courts to address local matters first.
β Use suo motu powers primarily for systemic failures and constitutional crises.
β Strengthen trial courts through better infrastructure, staffing, and training.
β Establish objective guidelines for initiating suo motu proceedings.
π Way Forward
β Formulate transparent criteria for exercising suo motu jurisdiction.
β Focus on long-term judicial reforms rather than case-specific monitoring.
β Fill judicial vacancies and modernize court administration.
β Enhance coordination between the Supreme Court, High Courts, and subordinate judiciary.
β Preserve the exceptional nature of suo motu intervention.
π Significance
β Suo motu cognisance remains a powerful constitutional tool for protecting justice.
β However, excessive reliance may create perceptions of judicial paternalism and institutional overreach.
β A balance between judicial activism and judicial restraint is essential for maintaining constitutional governance.
π UPSC Relevance
β Prelims: Article 32, Article 142, PIL, Suo Motu Cognisance.
β Mains (GS2): Judiciary, Judicial Activism, Separation of Powers, Constitutional Governance, Judicial Reforms.
β Essay: Judicial Activism vs Judicial Restraint; Role of Judiciary in Democracy.
#GS2 #Polity #mains
β€4
Forwarded from UPSC ethics
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π Paramutation
π Why in News?
β New research suggests that genes inherited from one parent can sometimes silence corresponding genes inherited from the other parent
β The effect may persist across generations, challenging conventional understanding of genetic inheritance
π What is Paramutation?
β Paramutation is an epigenetic phenomenon in which one allele of a gene can induce a heritable change in the expression of another allele
β The affected gene may be silenced or altered in its activity without changing its underlying DNA sequence
β The phenomenon involves epigenetic modifications, including the addition of methyl groups to DNA
π How Does it Work?
β Genes inherited from both parents normally contribute to genetic traits through their DNA sequences
β In paramutation, one gene copy can influence the expression of another corresponding copy
β DNA methylation can modify gene activity by affecting whether a gene is switched on or off
β The altered expression pattern can potentially be transmitted to subsequent generations
π Why is it Important?
β Challenges the conventional Mendelian view of inheritance, where inherited traits are primarily explained through DNA sequence transmission
β Demonstrates that gene expression can be influenced by epigenetic mechanisms
β Highlights how environmental and cellular mechanisms can influence the functioning of inherited genes
β Has important implications for understanding hereditary diseases, development, and evolution
π Paramutation & Epigenetics
π Epigenetics
β Refers to changes in gene activity or expression without altering the underlying DNA sequence
β Major mechanisms include DNA methylation and modifications of proteins associated with DNA
β Such changes can sometimes be heritable
π Key Distinction
β Mutation β Changes the DNA sequence
β Epigenetic change β Changes gene expression without necessarily changing the DNA sequence
β Paramutation β One allele induces a heritable epigenetic change in another allele
π Prelims Facts
β Paramutation β Heritable interaction between alleles causing altered gene expression
β Mechanism β Associated with epigenetic modifications, including DNA methylation
β DNA sequence β Not necessarily altered
β Significance β Challenges the conventional understanding of inheritance and gene expression
#GS3
#prelims
#science_technology
#science_and_technology
Join https://t.me/PIB_UPSC
https://t.me/upsc_science_and_technology
π Why in News?
β New research suggests that genes inherited from one parent can sometimes silence corresponding genes inherited from the other parent
β The effect may persist across generations, challenging conventional understanding of genetic inheritance
π What is Paramutation?
β Paramutation is an epigenetic phenomenon in which one allele of a gene can induce a heritable change in the expression of another allele
β The affected gene may be silenced or altered in its activity without changing its underlying DNA sequence
β The phenomenon involves epigenetic modifications, including the addition of methyl groups to DNA
π How Does it Work?
β Genes inherited from both parents normally contribute to genetic traits through their DNA sequences
β In paramutation, one gene copy can influence the expression of another corresponding copy
β DNA methylation can modify gene activity by affecting whether a gene is switched on or off
β The altered expression pattern can potentially be transmitted to subsequent generations
π Why is it Important?
β Challenges the conventional Mendelian view of inheritance, where inherited traits are primarily explained through DNA sequence transmission
β Demonstrates that gene expression can be influenced by epigenetic mechanisms
β Highlights how environmental and cellular mechanisms can influence the functioning of inherited genes
β Has important implications for understanding hereditary diseases, development, and evolution
π Paramutation & Epigenetics
π Epigenetics
β Refers to changes in gene activity or expression without altering the underlying DNA sequence
β Major mechanisms include DNA methylation and modifications of proteins associated with DNA
β Such changes can sometimes be heritable
π Key Distinction
β Mutation β Changes the DNA sequence
β Epigenetic change β Changes gene expression without necessarily changing the DNA sequence
β Paramutation β One allele induces a heritable epigenetic change in another allele
π Prelims Facts
β Paramutation β Heritable interaction between alleles causing altered gene expression
β Mechanism β Associated with epigenetic modifications, including DNA methylation
β DNA sequence β Not necessarily altered
β Significance β Challenges the conventional understanding of inheritance and gene expression
#GS3
#prelims
#science_technology
#science_and_technology
Join https://t.me/PIB_UPSC
https://t.me/upsc_science_and_technology
β€5π2