Error in Figure
https://jamanetwork.com/journals/jama/fullarticle/2845483
The Original Investigation titled “An Adaptive Behavioral Intervention for Weight Loss Management: A Randomized Clinical Trial,” published on May 14, 2024, was corrected to fix an error in Figure 2 in which the x-axis labels for baseline and 6 months were inadvertently swapped for the wireless feedback system plus coaching group. This article was corrected online.
https://jamanetwork.com/journals/jama/fullarticle/2845483
The Original Investigation titled “An Adaptive Behavioral Intervention for Weight Loss Management: A Randomized Clinical Trial,” published on May 14, 2024, was corrected to fix an error in Figure 2 in which the x-axis labels for baseline and 6 months were inadvertently swapped for the wireless feedback system plus coaching group. This article was corrected online.
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Heat and Pregnancy
https://jamanetwork.com/journals/jama/fullarticle/2845482
This JAMA Insights discusses current evidence about risks to the health of pregnant individuals from ambient heat (hot weather, high indoor temperatures, and occupational exposures) and how these risks can be managed.
https://jamanetwork.com/journals/jama/fullarticle/2845482
This JAMA Insights discusses current evidence about risks to the health of pregnant individuals from ambient heat (hot weather, high indoor temperatures, and occupational exposures) and how these risks can be managed.
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Stillbirth Rates in the US
https://jamanetwork.com/journals/jama/fullarticle/2845481
To the Editor A recent study described contemporary stillbirth rates in the US using a large national cohort of commercially insured pregnancies. Among the study’s findings, Figure 1 in the article is particularly instructive. This figure depicts the prospective fetal mortality rate by gestational age at delivery and the percentage of stillbirths at a given gestational week with at least 1 clinical risk factor. It clearly illustrates the rise in fetal mortality beginning at 39 weeks’ gestation, which is consistent with observations from large population-based cohorts. Notably, this figure shows that the risk of stillbirth is not limited to high-risk pregnancies and increases substantially near term, with approximately 40% of stillbirths occurring without any identifiable risk factor other than a gestational age of more than 39 weeks.
https://jamanetwork.com/journals/jama/fullarticle/2845481
To the Editor A recent study described contemporary stillbirth rates in the US using a large national cohort of commercially insured pregnancies. Among the study’s findings, Figure 1 in the article is particularly instructive. This figure depicts the prospective fetal mortality rate by gestational age at delivery and the percentage of stillbirths at a given gestational week with at least 1 clinical risk factor. It clearly illustrates the rise in fetal mortality beginning at 39 weeks’ gestation, which is consistent with observations from large population-based cohorts. Notably, this figure shows that the risk of stillbirth is not limited to high-risk pregnancies and increases substantially near term, with approximately 40% of stillbirths occurring without any identifiable risk factor other than a gestational age of more than 39 weeks.
Fertility Preservation in People With Cancer
https://jamanetwork.com/journals/jama/fullarticle/2845588
This JAMA Clinical Guidelines Synopsis summarizes the American Society of Clinical Oncology’s 2025 updated recommendations on fertility preservation in people with cancer.
https://jamanetwork.com/journals/jama/fullarticle/2845588
This JAMA Clinical Guidelines Synopsis summarizes the American Society of Clinical Oncology’s 2025 updated recommendations on fertility preservation in people with cancer.
Changes in Organ Donation After Circulatory Death in the US
https://jamanetwork.com/journals/jama/fullarticle/2845586
This study describes secular trends in organ donation after circulatory death in the United States between 2000 and 2025.
https://jamanetwork.com/journals/jama/fullarticle/2845586
This study describes secular trends in organ donation after circulatory death in the United States between 2000 and 2025.
Review of Metabolic Dysfunction–Associated Steatotic Liver Disease In Adults
https://jamanetwork.com/journals/jama/fullarticle/2845585
To the Editor A recent Review, which provided a detailed account of the current state of care for patients with metabolic dysfunction–associated steatohepatitis (MASH), outlined a diagnostic algorithm centered on sequential use of the Fibrosis-4 (FIB-4) index followed by vibration-controlled transient elastography. However, recent data highlighted that this strategy has a substantial risk of not identifying patients with metabolic dysfunction–associated steatotic liver disease (MASLD) who may benefit most from early treatment.
https://jamanetwork.com/journals/jama/fullarticle/2845585
To the Editor A recent Review, which provided a detailed account of the current state of care for patients with metabolic dysfunction–associated steatohepatitis (MASH), outlined a diagnostic algorithm centered on sequential use of the Fibrosis-4 (FIB-4) index followed by vibration-controlled transient elastography. However, recent data highlighted that this strategy has a substantial risk of not identifying patients with metabolic dysfunction–associated steatotic liver disease (MASLD) who may benefit most from early treatment.
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Review of Metabolic Dysfunction–Associated Steatotic Liver Disease in Adults—Reply
https://jamanetwork.com/journals/jama/fullarticle/2845584
In Reply We appreciate the comments from Dr Khan and colleagues on our Review article on MASLD.
https://jamanetwork.com/journals/jama/fullarticle/2845584
In Reply We appreciate the comments from Dr Khan and colleagues on our Review article on MASLD.
Audio Highlights February 27, 2026
https://jamanetwork.com/journals/jama/fullarticle/2845915
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
https://jamanetwork.com/journals/jama/fullarticle/2845915
Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.
CMS: States No Longer Required to Report Immunizations
https://jamanetwork.com/journals/jama/fullarticle/2845869
The Centers for Medicare and Medicaid Services (CMS) has announced the removal of immunization measures from the Child Core Set and Adult Core Set in a letter to state health officials.
https://jamanetwork.com/journals/jama/fullarticle/2845869
The Centers for Medicare and Medicaid Services (CMS) has announced the removal of immunization measures from the Child Core Set and Adult Core Set in a letter to state health officials.
Automatic Screening Increases Urinary Incontinence Diagnosis and Treatment
https://jamanetwork.com/journals/jama/fullarticle/2845868
Automated screening and education for urinary incontinence in primary care settings may increase awareness and promote treatment among women, according to research published in JAMA Internal Medicine.
https://jamanetwork.com/journals/jama/fullarticle/2845868
Automated screening and education for urinary incontinence in primary care settings may increase awareness and promote treatment among women, according to research published in JAMA Internal Medicine.
About 1 in 5 US Youth Had Obesity in 2024
https://jamanetwork.com/journals/jama/fullarticle/2845867
Data from more than 6 million US children found that about 20% of those aged 2 to 19 years had obesity.
https://jamanetwork.com/journals/jama/fullarticle/2845867
Data from more than 6 million US children found that about 20% of those aged 2 to 19 years had obesity.
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Food Quality Beats Macronutrient Focus for Heart Health
https://jamanetwork.com/journals/jama/fullarticle/2845866
This Medical News article discusses new findings that carbohydrate and fat composition are not as important as diet quality for cardiovascular health.
https://jamanetwork.com/journals/jama/fullarticle/2845866
This Medical News article discusses new findings that carbohydrate and fat composition are not as important as diet quality for cardiovascular health.
Timing and Location in Minimally Invasive ICH Surgery
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845748
To the Editor Arthur and colleagues should be congratulated for conducting the MIND (Artemis in the Removal of Intracerebral Hemorrhage) randomized clinical trial, which adds important evidence to the discussion of minimally invasive surgery (MIS) for supratentorial intracerebral hemorrhage (ICH). The investigators achieved excellent technical results, with the majority of surgical patients reaching a residual clot volume of 15 mL or less. Despite this, the overall trial did not show benefit for mortality or disability at 180 days, which is an important and sobering message for the field.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845748
To the Editor Arthur and colleagues should be congratulated for conducting the MIND (Artemis in the Removal of Intracerebral Hemorrhage) randomized clinical trial, which adds important evidence to the discussion of minimally invasive surgery (MIS) for supratentorial intracerebral hemorrhage (ICH). The investigators achieved excellent technical results, with the majority of surgical patients reaching a residual clot volume of 15 mL or less. Despite this, the overall trial did not show benefit for mortality or disability at 180 days, which is an important and sobering message for the field.
Timing and Location in Minimally Invasive ICH Surgery—Reply
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845747
In Reply We value the thoughtful comments from Zhou and Zhang regarding intracerebral hemorrhage (ICH) location and timing of minimally invasive surgery (MIS) from the MIND (Artemis in the Removal of Intracerebral Hemorrhage) randomized clinical trial. We agree that these factors warrant closer examination and appreciate the opportunity to clarify aspects of our analysis.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845747
In Reply We value the thoughtful comments from Zhou and Zhang regarding intracerebral hemorrhage (ICH) location and timing of minimally invasive surgery (MIS) from the MIND (Artemis in the Removal of Intracerebral Hemorrhage) randomized clinical trial. We agree that these factors warrant closer examination and appreciate the opportunity to clarify aspects of our analysis.
Low-Dose Lithium for Mild Cognitive Impairment
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845746
This pilot randomized clinical trial evaluates the feasibility, safety, and methodological considerations of low-dose lithium treatment in older adults with mild cognitive impairment.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845746
This pilot randomized clinical trial evaluates the feasibility, safety, and methodological considerations of low-dose lithium treatment in older adults with mild cognitive impairment.
Catheter Ablation and Oral Anticoagulation in Atrial Fibrillation
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845745
This randomized clinical trial investigates if catheter ablation plus standard therapy reduces the risk of recurrent stroke or composite outcomes in patients with atrial fibrillation and a recent history of stroke.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2845745
This randomized clinical trial investigates if catheter ablation plus standard therapy reduces the risk of recurrent stroke or composite outcomes in patients with atrial fibrillation and a recent history of stroke.
Electrocardiography Unmasking the Cause of Unexplained Coma
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2845666
This case report describes a man in his 60s who presented with myxedema coma due to secondary hypothermia, which was revealed on electrocardiography.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2845666
This case report describes a man in his 60s who presented with myxedema coma due to secondary hypothermia, which was revealed on electrocardiography.
Inflammatory Knee Osteoarthritis Does Not Improve With Oral Diacerein
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2845665
Osteoarthritis (OA) of the knee results from deterioration of articular cartilage, often followed by hypertrophy of new bone at the periphery of the joint and synovial inflammation or synovitis. As knee OA progresses into more advanced stages, inflammation and pain prevalence occurs in well over 50%. The pathological development of OA occurs in stages. The cartilage matrix is first broken down by proteolytic enzymes. Matrix fragments are released into joint fluid, which can promote inflammation in the synovial membrane. Inflammation of the synovial membrane creates a vicious cycle, in which the cartilage matrix is further degraded, subsequently provoking more synovial inflammation. Inflammation in knee OA is primarily due to the presence of the cytokine interleukin 1 (IL-1β). This cytokine can stimulate its own production, which increases the synthesis of catabolic factors that degrade cartilage, resulting in chondrocyte apoptosis and decreasing cartilage macromolecule synthesis.
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2845665
Osteoarthritis (OA) of the knee results from deterioration of articular cartilage, often followed by hypertrophy of new bone at the periphery of the joint and synovial inflammation or synovitis. As knee OA progresses into more advanced stages, inflammation and pain prevalence occurs in well over 50%. The pathological development of OA occurs in stages. The cartilage matrix is first broken down by proteolytic enzymes. Matrix fragments are released into joint fluid, which can promote inflammation in the synovial membrane. Inflammation of the synovial membrane creates a vicious cycle, in which the cartilage matrix is further degraded, subsequently provoking more synovial inflammation. Inflammation in knee OA is primarily due to the presence of the cytokine interleukin 1 (IL-1β). This cytokine can stimulate its own production, which increases the synthesis of catabolic factors that degrade cartilage, resulting in chondrocyte apoptosis and decreasing cartilage macromolecule synthesis.
Insufficient Sleep in Adolescents and the Need for System Changes
https://jamanetwork.com/journals/jama/fullarticle/2845760
Insufficient sleep is one of the most common health risks in adolescents and is associated with worse cognitive performance and academic achievement, as well as depression, other mental health conditions, and physical concerns. The American Academy of Sleep Medicine and American Academy of Pediatrics (AAP) recommend adolescents aged 13 to 18 years sleep for 8 to 10 hours each night. Yet, studies have found that adequate sleep eludes most adolescents.
https://jamanetwork.com/journals/jama/fullarticle/2845760
Insufficient sleep is one of the most common health risks in adolescents and is associated with worse cognitive performance and academic achievement, as well as depression, other mental health conditions, and physical concerns. The American Academy of Sleep Medicine and American Academy of Pediatrics (AAP) recommend adolescents aged 13 to 18 years sleep for 8 to 10 hours each night. Yet, studies have found that adequate sleep eludes most adolescents.
Management and Consequences of Genotype-Positive Familial Hypercholesterolemia in the US
https://jamanetwork.com/journals/jamacardiology/fullarticle/2845800
This cohort study identifies genotype-positive familial hypercholesterolemia in a national US cohort and describes its prevalence, consequences, and lipid-lowering management.
https://jamanetwork.com/journals/jamacardiology/fullarticle/2845800
This cohort study identifies genotype-positive familial hypercholesterolemia in a national US cohort and describes its prevalence, consequences, and lipid-lowering management.