Let's Talk Medicine
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The signs of multiple myeloma can be remembered using the mnemonic CRAB:

- Calcium (hypercalcemia)
- Renal failure
- Anemia
- Bone lesions (lytic)
Let's Talk Medicine pinned «🔴 The signs of multiple myeloma can be remembered using the mnemonic CRAB: - Calcium (hypercalcemia) - Renal failure - Anemia - Bone lesions (lytic)»
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- For a positive TB exposure and a positive PPD test (but no active disease), treatment is INH only.

- If the patient has active TB, multiagent therapy is indicated.
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The most common electrolyte/acid–base abnormality seen with severe diarrhea is metabolic acidosis and hypokalemia.
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- Upright chest x-ray is the best initial test for the evaluation of free air under the diaphragm.

- Free air under the diaphragm indicates a perforation of the bowel.
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The most common cause of esophageal perforation is iatrogenic. The most common procedure that causes an esophageal perforation is upper endoscopy.
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Neuroblastoma are statistically the most common cancers in infancy and the most common extracranial solid malignancy.
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Pulses:
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- Suspect Turner syndrome in females with pathologic short stature.

- Suspect craniopharyngioma if short stature and vision problems.
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- Larynx is the most common site of foreign body aspiration in children age <1 year.

- In children age >1 year, think trachea or right mainstem bronchus.
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VACTERL Association Nonrandom association of birth defects:


Vertebral anomalies
Anal atresia
Cardiac defect
TracheoEsophageal fistula
Renal anomalies
Limb abnormalities
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Rhinitis Medicamentosa:

Rebound nasal congestion. Occurs with prolonged use (>5-7 d) of vasoconstrictive intranasal medications. Patient may become dependent, requiring more frequent dosing to achieve the same decongestant effect.
Let's Talk Medicine pinned «🔴 Rhinitis Medicamentosa: Rebound nasal congestion. Occurs with prolonged use (>5-7 d) of vasoconstrictive intranasal medications. Patient may become dependent, requiring more frequent dosing to achieve the same decongestant effect.»
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Dyspepsia red flags:

- Weight Loss
- Dysphagia
- Persistent vomiting
- GI bleeding (hematemesis, hematochezia, melena)
- Onset age >50
DDx of Erectile Dysfunction:

PENIS ⬇️

Psychogenic
Endocrine (type 2 DM, testosterone)
Neurogenic (type 2 DM, post-operative)
Insufficiency of blood (atherosclerosis)
Substances
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- ALT > AST = most causes of hepatitis.

- AST > ALT = alcoholic liver disease or other causes of hepatitis (i.e. non-alcoholic liver disease) that have progressed to advanced cirrhosis.
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Fanconi anemia:

- Absent/hypoplastic thumbs
- All cell lines depressed
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Patients without a functioning spleen are predisposed to infection with encapsulated organisms. Pneumococcal vaccines 13 (PCV13) and 23 (PPSV23) are necessary.
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In congenital adrenal hyperplasia, 90% or more of cases are due to 21-hydroxylase deficiency.