'Brain stars' store our memories like a microscopic filing cabinet | Researchers found that fear conditioning in mice – a learning process – triggered a subset of astrocytes that express the c-Fos gene, which plays a key role in circuitry in the brain.
Read Full Article
#BrainResearch #MemoryStorage #Astrocytes #FearConditioning #Neuroscience
Read Full Article
#BrainResearch #MemoryStorage #Astrocytes #FearConditioning #Neuroscience
New Atlas
'Brain stars' store our memories like a microscopic filing cabinet
Fascinating new findings into how clusters of 'brain stars' retain memories has changed what we know about how they're held in our minds.
❤1🔥1
Goodbye to traumatic memories: researchers discovered that by artificially acidifying a special type of cell (astrocytes) in mice, they could prevent long-term memories from being recalled without affecting short-term memory
Read Full Article
#TraumaRecovery #Astrocytes #MemoryResearch #Neuroscience #MentalHealth
Read Full Article
#TraumaRecovery #Astrocytes #MemoryResearch #Neuroscience #MentalHealth
Tohoku University Official English Website
Saying Goodbye to Traumatic Memories: Astrocytic Manipulation of the Fate of Memory
Controlling memories in mice means forgetting a light zap, but in humans it could mean letting go of deeply traumatic events.
😁1🤔1💩1
For decades, scientists searching for the root cause of depression have mostly focused on neurons 🧠 and their chemical signals. But a recent study in Cell 📖 points to a new role for astrocytes 🌟.
Read Full Article
#DepressionResearch #Astrocytes #Neuroscience #MentalHealth #ScientificStudy
Read Full Article
#DepressionResearch #Astrocytes #Neuroscience #MentalHealth #ScientificStudy
PNAS
Astrocytes may play critical role in depression
Astrocytes, the star-shaped glial cells known for providing structural and metabolic support to neurons, may actually have a role in the mechanisms underlying depression. Image credit: JOSE CALVO/Science Source
Instead of neurons, brain cells called astrocytes dominate in shaping responses to signals involved in vigilance 🧠, a mouse study shows. This suggests that astrocytes should be a greater focus as therapeutic targets for treating attention, memory, and emotional disorders 💡🧩.
Read Full Article
#Astrocytes #BrainHealth #Neuroscience #MentalHealthResearch #TherapeuticTargets
Read Full Article
#Astrocytes #BrainHealth #Neuroscience #MentalHealthResearch #TherapeuticTargets
WashU Medicine
Overlooked cell type orchestrates brain rewiring | WashU Medicine
Rather than neurons, brain cells known as astrocytes take charge in shaping response to signal involved in vigilance, mouse study shows
Overlooked cells might explain the human brain’s huge storage capacity 🧠✨: « MIT researchers developed a new model of memory that includes critical contributions from astrocytes, a class of brain cells. »
Read Full Article
#BrainResearch #Astrocytes #MemoryScience #MITInnovation #Neuroscience
Read Full Article
#BrainResearch #Astrocytes #MemoryScience #MITInnovation #Neuroscience
MIT News
Overlooked cells might explain the human brain’s huge storage capacity
MIT researchers have a new hypothesis for how brain cells called astrocytes might contribute to memory storage in the brain. Their model, known as dense associative memory, would help explain the brain’s massive storage capacity.
High-fat diets and obesity reshape star-shaped cells called astrocytes in the brain’s striatum that help regulate pleasure from eating. Modifying these cells in mice not only impacted metabolism but also restored cognitive abilities impaired by obesity, such as relearning tasks. 🍔🧠✨
Read Full Article
#HighFatDiets #ObesityResearch #Astrocytes #BrainHealth #CognitiveRestoration
Read Full Article
#HighFatDiets #ObesityResearch #Astrocytes #BrainHealth #CognitiveRestoration
Nature
Striatal astrocytes modulate behavioral flexibility and whole-body metabolism in mice
Nature Communications - Striatal neural circuits control reward-associated behaviors but the role of astrocytes is still unclear. Here, the authors show that chemogenetic manipulation of striatal...
🐳2
From postsynaptic neurons to astrocytes: the link between glutamate metabolism, Alzheimer’s disease 🧠 and Parkinson’s disease 🧑⚕️.
Read Full Article
#Neuroscience #GlutamateMetabolism #AlzheimersDisease #ParkinsonsDisease #Astrocytes
Read Full Article
#Neuroscience #GlutamateMetabolism #AlzheimersDisease #ParkinsonsDisease #Astrocytes
De Gruyter Brill
From postsynaptic neurons to astrocytes: the link between glutamate metabolism, Alzheimer’s disease and Parkinson’s disease
Glutamate is not only the main excitatory neurotransmitter of the human central nervous system, but also a potent neurotoxin. Therefore, maintaining low-dose, non-toxic extracellular glutamate concentrations between synapses to ensure the reliability of synaptic…
❤1
Restoring a specific protein could rewire the brain in Down syndrome 🧠🔄. Researchers have found that mouse models of several neurodevelopmental disorders, including Down syndrome, have altered levels of astrocyte proteins during development. 🐭🧬
Read Full Article
#DownSyndrome #Neurodevelopment #BrainHealth #Astrocytes #ResearchInnovation
Read Full Article
#DownSyndrome #Neurodevelopment #BrainHealth #Astrocytes #ResearchInnovation
Cell Reports
Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome
Brandebura et al. demonstrate that aberrant downregulation of the secreted molecule
pleiotrophin contributes to neuronal phenotypes in a Down syndrome mouse model. Targeting
overexpression of pleiotrophin to astrocytes improves neuronal morphological and…
pleiotrophin contributes to neuronal phenotypes in a Down syndrome mouse model. Targeting
overexpression of pleiotrophin to astrocytes improves neuronal morphological and…
❤1🤯1🙏1
Science News
Once Thought To Support Neurons, Astrocytes Turn Out To Be in Charge Read Full Article #AstrocytesInCharge #GlialPower #NeuroscienceBreakthrough #BrainCells #AstrocyteLeadership
🧠 **Astrocytes Revealed as Brain's Supervisors, Not Just Support Cells**
* New research published in Science in 2025 indicates that astrocytes, previously thought to be mere support cells for neurons, act as supervisors that tune brain circuits and control overall brain states (e.g., alertness, mood). Experiments in mice, zebra fish, and fruit flies highlight their crucial role in neuromodulation.
⚡ **Astrocytes Control Behavioral State Switches**
* Studies demonstrate that astrocytes play a key role in sudden behavioral changes. For instance, in zebra fish, astrocytes release ATP (converted to adenosine) to suppress swimming neurons, leading to a "giving up" behavior when faced with a futile task. This suggests astrocytes are integral to switching brain states.
💡 **Evolutionarily Conserved Mechanism for Brain Function**
* Parallel findings across fruit flies, zebra fish, and mice reveal an evolutionarily conserved pathway where astrocytes, triggered by neuromodulators like norepinephrine, release molecules that significantly affect neural circuits. This challenges previous models of brain function that solely focused on neurons.
#Neuroscience #BrainResearch #Astrocytes
(⚠️ Formatting disabled due to Markdown error)
* New research published in Science in 2025 indicates that astrocytes, previously thought to be mere support cells for neurons, act as supervisors that tune brain circuits and control overall brain states (e.g., alertness, mood). Experiments in mice, zebra fish, and fruit flies highlight their crucial role in neuromodulation.
⚡ **Astrocytes Control Behavioral State Switches**
* Studies demonstrate that astrocytes play a key role in sudden behavioral changes. For instance, in zebra fish, astrocytes release ATP (converted to adenosine) to suppress swimming neurons, leading to a "giving up" behavior when faced with a futile task. This suggests astrocytes are integral to switching brain states.
💡 **Evolutionarily Conserved Mechanism for Brain Function**
* Parallel findings across fruit flies, zebra fish, and mice reveal an evolutionarily conserved pathway where astrocytes, triggered by neuromodulators like norepinephrine, release molecules that significantly affect neural circuits. This challenges previous models of brain function that solely focused on neurons.
#Neuroscience #BrainResearch #Astrocytes
(⚠️ Formatting disabled due to Markdown error)