Previously unknown mechanism of inflammation shows in mice Covid spike protein directly binds to blood protein fibrin, cause of unusual clotting. Also activates destructive immune response in the brain, likely cause of reduced cognitive function. Immunotherapy progressed to Phase 1 clinical trials.
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#CovidResearch #InflammationMechanism #ImmuneResponse #ClinicalTrials #CognitiveHealth
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#CovidResearch #InflammationMechanism #ImmuneResponse #ClinicalTrials #CognitiveHealth
Nature
Fibrin drives thromboinflammation and neuropathology in COVID-19
Nature - Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.
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