Obesity 🍔 impairs gut repair 🩺 via AFABP-mediated iron overload ⚙️ in intestinal stem cells 🧬
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#Obesity #GutHealth #IntestinalStemCells #IronOverload #AFABP
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#Obesity #GutHealth #IntestinalStemCells #IronOverload #AFABP
PubMed
Obesity impairs gut repair via AFABP-mediated iron overload in intestinal stem cells - PubMed
Obesity impairs the function of multiple organs, but its effect on gut regeneration remains poorly defined. Here, we show that adipocyte fatty acid-binding protein (AFABP), an adipokine involved in fatty acid transport, impedes intestinal repair by disrupting…
Supplementing the guts of older mice with fecal microbiota from younger ones reversed one aspect of age-related decline, driven by increased intestinal stem cell activity that maintains the intestinal walls.
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#YoungGutRejuvenation #FecalMicrobiotaTransplant #GutAgingResearch #IntestinalStemCells #AgingScience
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#YoungGutRejuvenation #FecalMicrobiotaTransplant #GutAgingResearch #IntestinalStemCells #AgingScience
ScienceAlert
Poop From Young Donors Reverses Age-Related Decline in The Guts of Older Mice
Gross.
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