Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that ‘switching off’ a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%.

New research dispels the notion that human beings can continue to radically extend their lifespan

Nature - Weight loss and metabolic improvements do not explain the longevity benefits of severe dietary restrictions, research in mice shows.

Maria Branyas Morera, US-born supercentenarian who died in Spain last August, found to have microbiota of an infant

Background/Objectives: Hypercholesterolemia is commonly viewed as a risk factor for coronary heart disease; however, several studies have reported an inverse relationship between cholesterol levels and cardiovascular mortality, particularly in older adults.…

A large study tracking older adults over a decade found that higher psychological well-being predicts better cognitive health—and vice versa. The strongest effects were seen for people with a strong sense of purpose.

Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.

Nature - An analysis of how various tissues age is the latest to suggest that ageing does not march to a steady beat.

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Nature Aging - In this Perspective, members of the Aging Biomarker Consortium outline the X-Age Project, an Aging Biomarker Consortium plan for building standardized aging clocks in China. The...

What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades. Now scientists have uncovered just how they repair their DNA – and it has the potential to be harnessed for humans to do the same.

The quest for immortality.

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage. These cellular issues impair the ability to maintain the myelin sheath (the protective covering around nerve fibers), which leads to age…

Nature - Data collected from zoos and aquariums worldwide show that hormonal contraception or permanent surgical sterilization in mammals increase life expectancy, with different mechanisms in...

Mitochondrial respiratory supercomplex assembly factor COX7RP improves metabolic homeostasis and contributes to lifespan extension in mice. The overexpression of COX7RP reduces white adipose tissue m...

Nature - Assessing thymic function and health has highlighted the lifelong importance of the thymus as an organ that could be targeted to improve health outcomes, protect against disease and...