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Meta-analysis of multiple MDMA-PTSD clinical trials retracted over allegations of unethical conduct, data manipulation, and financial conflict of interests.

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#MDMA #PTSD #clinicaltrials #retracted #ethicsgoneawry
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Global 🌍 pharmacovigilance analysis of classic psychedelics and MDMA reveals that while psychiatric adverse events are frequent in real-world settings, severe physical complications remain rare. The study suggests high abuse reports likely stem from polysubstance use rather than the drugs alone.

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#globalpharmacovigilance #psychedelics #mdma #adverseevents #polysubstanceuse
A new pilot study suggests MDMA-assisted therapy may offer durable relief for major depressive disorder 🧠💊, with many patients maintaining reduced symptoms and improved daily functioning months after treatment in a controlled hospital setting 🏥, while underscoring the need for larger controlled trial 🔬.

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#MDMA #therapy #depression #mentalhealth #research
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Science News
Recreational ecstasy use is linked to lasting memory impairments. A new analysis indicates that people who use the drug recreationally perform worse on cognitive tests than those who have never used it. Read Full Article #MemoryImpact #EcstasyRisks #CognitiveHealth…
* 🧠 A new meta-analysis published in the *Journal of Psychopharmacology* suggests that recreational MDMA (ecstasy) use may lead to lasting learning and memory difficulties, even after months or years of abstinence.

* 📉 The analysis found that individuals with a history of MDMA use performed significantly worse on memory tests compared to those who had never used the drug. Notably, verbal memory deficits were most pronounced, and cognitive performance remained similar for current users and those abstinent for at least six months, with no improvement observed even after two years of abstinence.

* ⚠️ Researchers caution that the available evidence is generally of low quality, with limitations including cross-sectional study designs, the prevalence of polydrug use, inconsistent drug purity, and changes in modern ecstasy tablet strength, all of which complicate isolating MDMA's specific effects and may suggest higher risks for current users.

#MDMA #Ecstasy #CognitiveHealth

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