Chronic stress upregulates cortisol and generates ROS, driving kidney disease progression. The review shows that sustained HPA-axis activation promotes mitochondrial dysfunction, oxidative inflammation, and fibrosis in renal tissue. 🧠💔🧪🌱
Read Full Article
#ChronicStress #Cortisol #KidneyDisease #MitochondrialDysfunction #OxidativeInflammation
Read Full Article
#ChronicStress #Cortisol #KidneyDisease #MitochondrialDysfunction #OxidativeInflammation
MDPI
Stress Pathways in Chronic Kidney Disease: Linking Cortisol, Oxidative Stress, and Inflammation
This review aims to synthesize current evidence on the role of chronic stress and hypothalamic–pituitary–adrenal (HPA) axis dysregulation in the pathogenesis of chronic kidney disease (CKD). The focus is on the interplay between cortisol, oxidative stress…
❤2