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We may now know how the placebo effect relieves pain: A newly identified brain pathway in mice could explain why placebos, or interventions designed to have no therapeutic effect, still relieve pain.

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#PlaceboEffect#PainRelief#BrainPathway#TherapeuticInterventions#ResearchDiscovery
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US FDA approves suzetrigine, the first non-opioid painkiller in decades, that delivers opioid-level pain suppression without the risks of addiction, sedation or overdose. A new study outlines its pharmacology and mechanism of action.

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#Suzetrigine #PainRelief #NonOpioid #FDAApproval #Pharmacology
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A new non-opioid painkiller, suzetrigine, has just been approved by the US drug regulator, the FDA. It is the first non-opioid painkiller the agency has approved in over two decades.

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#NonOpioid #PainRelief #Suzetrigine #FDAApproval #HealthInnovation
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This Cannabis-Inspired Drug Kills Pain Without Getting You High or Hooked | Researchers create a cannabis-derived compound that relieves pain without the risk of addiction or mind-altering effects.

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#CannabisResearch #PainRelief #NonAddictive #HealthInnovation #NaturalRemedies
Cannabis-like synthetic compound delivers pain relief without addictive high. Experiments on mice show it binds to pain-sensing cells like natural cannabis and delivers similar pain relief but does not cross blood-brain barrier, eliminating mind-altering side effects that make cannabis addictive.

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#CannabisResearch #PainRelief #SyntheticCompounds #HealthInnovation #AddictionFree
A trial in women with fibromyalgia showed that transplantation of healthy gut microbiome is associated with reduced pain and improved quality of life. Transplanting gut microbiome from women with fibromyalgia into mice induces pain. Replacing this with healthy microbiota alleviated pain in mice. 🦠💖✨

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#Fibromyalgia #GutHealth #PainRelief #Microbiome #QualityOfLife
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Opioid-level relief without the opioids 💊✨ That's the promise of SBI-810 | A new experimental painkiller has shown promise in dulling or eliminating pain in mice 🐭 while also avoiding the common opioid side effects including constipation 🚫 and sedation 😴.

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#PainRelief #SBI810 #InnovationInMedicine #OpioidAlternatives #ChronicPainSolutions
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Science News
Clinical Trial: Cannabis Topicals 🌿 Mitigate Pain, 💊 Improve Physical Functioning in Breast Cancer Patients 🎗️ Read Full Article #ClinicalTrial #CannabisTopicals #BreastCancer #PainManagement #HealthInnovation
✅ Breast cancer patients using topical balms with plant-derived cannabinoids reported reduced musculoskeletal pain after taking aromatase inhibitors, according to clinical trial data from the University of Minnesota.

✅ The study involved 21 patients randomly assigned to apply either CBD-dominant or THC-dominant balms three times daily for at least two weeks.

✅ Eighty-six percent of participants saw improvements in their pain scores, with THC-dominant balms showing the greatest relief. Benefits lasted up to four weeks.

✅ The cannabis balms were well-tolerated, did not affect estradiol levels, and showed no systemic THC absorption, suggesting they are safe for AIMSS patients.

#MedicalCannabis #BreastCancer #PainRelief
Science News
Spicy food can reduce extreme physical pain - Researchers found that holding a chili-infused gelatin cube in the mouth reduced how violently people reacted to high-intensity laser heat applied to their hands, though it did not relieve the feeling of minor…
🌶️ A small study found that holding chili-infused gelatin in your mouth reduced reactions to high-intensity laser heat on the hand, but not minor heat pain.

🧠 Capsaicin, found in chilies, activates receptors that signal heat and pain, but a burning mouth sensation can act as a temporary pain buffer for more intense discomfort.

🍽️ Individuals who regularly eat spicy foods showed lower pain sensitivity scores and a higher tolerance for physical distress.

#PainRelief #Capsaicin #Science
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Exercise rivals common pain meds. Researchers found that exercise can significantly reduce acute and chronic pain across a wide range of conditions including musculoskeletal, neurological, inflammatory, and cancer-related pain.

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#ExerciseMedicine #PainRelief #ScienceNews
Science News
Exercise rivals common pain meds. Researchers found that exercise can significantly reduce acute and chronic pain across a wide range of conditions including musculoskeletal, neurological, inflammatory, and cancer-related pain. Read Full Article #ExerciseMedicine…
💪 New Adelaide University research involving 221,279 participants found exercise significantly reduces acute and chronic pain across various conditions, offering relief comparable to or better than common pain medications.

⏱️ Shorter-duration and lower-intensity exercise programs, including those under two hours per week, delivered greater pain reductions, suggesting "more exercise isn't necessarily better."

🧘‍♀️ Exercise helps ease pain by releasing mood-boosting chemicals, calming inflammation, and altering the brain's response to pain, making it a powerful, yet underutilized, pain management tool.

#PainRelief #ExerciseBenefits #HealthResearch
Science News
Your favorite music could work best to help reduce the pain of small medical procedures: study of 204 patients found that listening to their favorite music reduced pain more effectively than Mozart or relaxation music Read Full Article #MusicTherapy #PainManagement…
🎶 Your favorite music may be the best choice for reducing pain during minor medical procedures, like getting an IV cannula.

🎵 A study found that listening to favorite tunes led to the greatest overall pain reduction. Mozart helped those already in pain, while relaxation music had no effect.

🔬 Researchers at University Hospital Zürich studied 204 patients undergoing MRIs. Their findings suggest increasing music's use in venous punctures for radiological procedures.

#MusicTherapy #PainRelief #HealthTech