Massage therapy’s effectiveness in pain relief is low to very low, according to a study analyzing 129 systematic reviews of literature published since 2018
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#MassageTherapy #PainRelief #SystematicReviews #Literature #HealthResearch
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Jamanetwork
Use of Massage Therapy for Pain, 2018-2023: A Systematic Review
This systematic review maps the certainty and quality of evidence reported by systematic reviews in 2018 to 2023 of massage therapy for pain in adults.
We may now know how the placebo effect relieves pain: A newly identified brain pathway in mice could explain why placebos, or interventions designed to have no therapeutic effect, still relieve pain.
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#PlaceboEffect#PainRelief#BrainPathway#TherapeuticInterventions#ResearchDiscovery
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#PlaceboEffect#PainRelief#BrainPathway#TherapeuticInterventions#ResearchDiscovery
New Scientist
We may finally know how the placebo effect relieves pain
A brain circuit discovered in mice could explain why placebo treatments ease pain in people
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Low-dose ketamine shows promise for pain relief in emergency department patients
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#LowDoseKetamine #PainRelief #EmergencyMedicine #MedicalResearch #InnovativeTherapy
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#LowDoseKetamine #PainRelief #EmergencyMedicine #MedicalResearch #InnovativeTherapy
Wiley Online Library
Low‐dose ketamine as an adjunct to morphine: A randomized controlled trial among patients with and without current opioid use
Background
Pain is a common complaint among patients presenting to the emergency department (ED), yet pain treatment is frequently suboptimal. The aim of this study was to determine the effectivenes...
Pain is a common complaint among patients presenting to the emergency department (ED), yet pain treatment is frequently suboptimal. The aim of this study was to determine the effectivenes...
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US FDA approves suzetrigine, the first non-opioid painkiller in decades, that delivers opioid-level pain suppression without the risks of addiction, sedation or overdose. A new study outlines its pharmacology and mechanism of action.
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#Suzetrigine #PainRelief #NonOpioid #FDAApproval #Pharmacology
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#Suzetrigine #PainRelief #NonOpioid #FDAApproval #Pharmacology
Nature
US drug agency approves potent painkiller — the first non-opioid in decades
Nature - The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.
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A new non-opioid painkiller, suzetrigine, has just been approved by the US drug regulator, the FDA. It is the first non-opioid painkiller the agency has approved in over two decades.
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#NonOpioid #PainRelief #Suzetrigine #FDAApproval #HealthInnovation
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#NonOpioid #PainRelief #Suzetrigine #FDAApproval #HealthInnovation
ScienceAlert
New Non-Opioid Painkiller First in Decades to Win FDA Approval
A game changer.
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This Cannabis-Inspired Drug Kills Pain Without Getting You High or Hooked | Researchers create a cannabis-derived compound that relieves pain without the risk of addiction or mind-altering effects.
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#CannabisResearch #PainRelief #NonAddictive #HealthInnovation #NaturalRemedies
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#CannabisResearch #PainRelief #NonAddictive #HealthInnovation #NaturalRemedies
ZME Science
This Cannabis-Inspired Drug Kills Pain Without Getting You High or Hooked
Researchers create a cannabis-derived compound that relieves pain without the risk of addiction or mind-altering effects.
Cannabis-like synthetic compound delivers pain relief without addictive high. Experiments on mice show it binds to pain-sensing cells like natural cannabis and delivers similar pain relief but does not cross blood-brain barrier, eliminating mind-altering side effects that make cannabis addictive.
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#CannabisResearch #PainRelief #SyntheticCompounds #HealthInnovation #AddictionFree
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#CannabisResearch #PainRelief #SyntheticCompounds #HealthInnovation #AddictionFree
UPI
Cannabis-like synthetic compound delivers pain relief without addictive high, study finds
March 5 (UPI) -- Researchers say they have reproduced the pain-relieving effects of cannabis with a synthesized compound that avoids the mind-altering, addictive qualities of the natural plant.
A new neuroimaging study has revealed that viewing nature can help ease how people experience pain, by reducing the brain activity linked to pain perception
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#NatureHeals #PainRelief #Neuroimaging #MentalWellness #BrainHealth
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#NatureHeals #PainRelief #Neuroimaging #MentalWellness #BrainHealth
University of Exeter
Watching nature scenes can reduce pain, new study shows
A new neuroimaging study has revealed that viewing nature can help ease how people experience pain, by reducing the brain activity linked to pain perception. Published in the journal Nature Communications and led by a
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Antidepressants provide little to no relief of low back pain and sciatica | One type of antidepressants reduced low back pain, but only trivially.
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#Antidepressants #LowBackPain #Sciatica #ChronicPain #PainRelief
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#Antidepressants #LowBackPain #Sciatica #ChronicPain #PainRelief
New Atlas
Antidepressants provide little to no relief of low back pain and sciatica
Despite being prescribed fairly commonly, a new study has found that antidepressants provide little to no benefit when it comes to relieving low back pain and sciatica. More research is needed into the long-term benefits and harms of using antidepressants…
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A trial in women with fibromyalgia showed that transplantation of healthy gut microbiome is associated with reduced pain and improved quality of life. Transplanting gut microbiome from women with fibromyalgia into mice induces pain. Replacing this with healthy microbiota alleviated pain in mice. 🦠💖✨
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#Fibromyalgia #GutHealth #PainRelief #Microbiome #QualityOfLife
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#Fibromyalgia #GutHealth #PainRelief #Microbiome #QualityOfLife
Neuron
The gut microbiota promotes pain in fibromyalgia
Cai et al. revealed that transplanting gut microbiota from women with fibromyalgia—a
chronic widespread pain condition of unknown etiology—into mice induces pain. It also
induces phenotypes commonly observed in patients, such as immune activation, metabolomic…
chronic widespread pain condition of unknown etiology—into mice induces pain. It also
induces phenotypes commonly observed in patients, such as immune activation, metabolomic…
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Opioid-level relief without the opioids 💊✨ That's the promise of SBI-810 | A new experimental painkiller has shown promise in dulling or eliminating pain in mice 🐭 while also avoiding the common opioid side effects including constipation 🚫 and sedation 😴.
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#PainRelief #SBI810 #InnovationInMedicine #OpioidAlternatives #ChronicPainSolutions
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#PainRelief #SBI810 #InnovationInMedicine #OpioidAlternatives #ChronicPainSolutions
New Atlas
Opioid-level relief without the opioids? That's the promise of SBI-810
A new experimental painkiller has shown promise in dulling or eliminating pain without the addictive qualities exhibited by today's most popular opioids. The drug also sidesteps common opioid side effects including constipation and sedation.
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How the placebo effect tricks the mind into relieving pain: the detailed mechanism of how the placebo effect reduces the perception of pain in rats has been uncovered 🐭💊✨
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#PlaceboEffect #PainRelief #Neuroscience #MindOverMatter #ResearchInsights
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#PlaceboEffect #PainRelief #Neuroscience #MindOverMatter #ResearchInsights
理化学研究所
How the placebo effect tricks the mind into relieving pain
RIKEN researchers have induced placebo analgesia in rodents and found that endogenous opioids activate the descending pain inhibitory system.
Drug-free pain relief game progresses to the next level in clinical trial 🎮🧠✨ | PainWave, a game-like app with a headset, it "trains" patients to rewire brain signals in order to relieve pain.
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#PainRelief #DrugFreeTherapy #ClinicalTrials #PainWave #MentalHealthInnovation
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#PainRelief #DrugFreeTherapy #ClinicalTrials #PainWave #MentalHealthInnovation
New Atlas
Drug-free pain relief game progresses to the next level in clinical trial
In the ongoing search to find a pain intervention that does away with the need for opioids – and bypasses drugs altogether – a new game-based system has shown huge promise in tackling chronic neuropathic pain. Using a game and a headset, it "trains" patients…
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Science News
Clinical Trial: Cannabis Topicals 🌿 Mitigate Pain, 💊 Improve Physical Functioning in Breast Cancer Patients 🎗️ Read Full Article #ClinicalTrial #CannabisTopicals #BreastCancer #PainManagement #HealthInnovation
✅ Breast cancer patients using topical balms with plant-derived cannabinoids reported reduced musculoskeletal pain after taking aromatase inhibitors, according to clinical trial data from the University of Minnesota.
✅ The study involved 21 patients randomly assigned to apply either CBD-dominant or THC-dominant balms three times daily for at least two weeks.
✅ Eighty-six percent of participants saw improvements in their pain scores, with THC-dominant balms showing the greatest relief. Benefits lasted up to four weeks.
✅ The cannabis balms were well-tolerated, did not affect estradiol levels, and showed no systemic THC absorption, suggesting they are safe for AIMSS patients.
#MedicalCannabis #BreastCancer #PainRelief
✅ The study involved 21 patients randomly assigned to apply either CBD-dominant or THC-dominant balms three times daily for at least two weeks.
✅ Eighty-six percent of participants saw improvements in their pain scores, with THC-dominant balms showing the greatest relief. Benefits lasted up to four weeks.
✅ The cannabis balms were well-tolerated, did not affect estradiol levels, and showed no systemic THC absorption, suggesting they are safe for AIMSS patients.
#MedicalCannabis #BreastCancer #PainRelief
Science News
Spicy food can reduce extreme physical pain - Researchers found that holding a chili-infused gelatin cube in the mouth reduced how violently people reacted to high-intensity laser heat applied to their hands, though it did not relieve the feeling of minor…
🌶️ A small study found that holding chili-infused gelatin in your mouth reduced reactions to high-intensity laser heat on the hand, but not minor heat pain.
🧠 Capsaicin, found in chilies, activates receptors that signal heat and pain, but a burning mouth sensation can act as a temporary pain buffer for more intense discomfort.
🍽️ Individuals who regularly eat spicy foods showed lower pain sensitivity scores and a higher tolerance for physical distress.
#PainRelief #Capsaicin #Science
🧠 Capsaicin, found in chilies, activates receptors that signal heat and pain, but a burning mouth sensation can act as a temporary pain buffer for more intense discomfort.
🍽️ Individuals who regularly eat spicy foods showed lower pain sensitivity scores and a higher tolerance for physical distress.
#PainRelief #Capsaicin #Science
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Exercise rivals common pain meds. Researchers found that exercise can significantly reduce acute and chronic pain across a wide range of conditions including musculoskeletal, neurological, inflammatory, and cancer-related pain.
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#ExerciseMedicine #PainRelief #ScienceNews
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#ExerciseMedicine #PainRelief #ScienceNews
Science News
Exercise rivals common pain meds. Researchers found that exercise can significantly reduce acute and chronic pain across a wide range of conditions including musculoskeletal, neurological, inflammatory, and cancer-related pain. Read Full Article #ExerciseMedicine…
💪 New Adelaide University research involving 221,279 participants found exercise significantly reduces acute and chronic pain across various conditions, offering relief comparable to or better than common pain medications.
⏱️ Shorter-duration and lower-intensity exercise programs, including those under two hours per week, delivered greater pain reductions, suggesting "more exercise isn't necessarily better."
🧘♀️ Exercise helps ease pain by releasing mood-boosting chemicals, calming inflammation, and altering the brain's response to pain, making it a powerful, yet underutilized, pain management tool.
#PainRelief #ExerciseBenefits #HealthResearch
⏱️ Shorter-duration and lower-intensity exercise programs, including those under two hours per week, delivered greater pain reductions, suggesting "more exercise isn't necessarily better."
🧘♀️ Exercise helps ease pain by releasing mood-boosting chemicals, calming inflammation, and altering the brain's response to pain, making it a powerful, yet underutilized, pain management tool.
#PainRelief #ExerciseBenefits #HealthResearch
Science News
Your favorite music could work best to help reduce the pain of small medical procedures: study of 204 patients found that listening to their favorite music reduced pain more effectively than Mozart or relaxation music Read Full Article #MusicTherapy #PainManagement…
🎶 Your favorite music may be the best choice for reducing pain during minor medical procedures, like getting an IV cannula.
🎵 A study found that listening to favorite tunes led to the greatest overall pain reduction. Mozart helped those already in pain, while relaxation music had no effect.
🔬 Researchers at University Hospital Zürich studied 204 patients undergoing MRIs. Their findings suggest increasing music's use in venous punctures for radiological procedures.
#MusicTherapy #PainRelief #HealthTech
🎵 A study found that listening to favorite tunes led to the greatest overall pain reduction. Mozart helped those already in pain, while relaxation music had no effect.
🔬 Researchers at University Hospital Zürich studied 204 patients undergoing MRIs. Their findings suggest increasing music's use in venous punctures for radiological procedures.
#MusicTherapy #PainRelief #HealthTech