Science News
Intranasal 👃 blood-brain barrier 🧱 bypass enables sequential mitochondria-targeted 🔋 bioengineered 🧬 nanolamellar 🧊 system for ischemic stroke therapy 🧠⚡ Read Full Article #intranasaldelivery #bloodbrainbarrierbypass #mitochondriatargeted #bioengineerednanolamellar…
🧠 New Stroke Therapy Breakthrough: Researchers have developed a "bioengineered nanolamellar system" (MM@BPPF) delivered via the nose to bypass the blood-brain barrier and target damaged brain cells after ischemic stroke.
🔬 How it Works: The system uses a novel coating that helps it specifically target injured brain regions and then the energy-producing parts of cells (mitochondria). It also delivers drugs sequentially to restore cell function and manage inflammation.
🚀 Potential Impact: This intranasal delivery method shows promise for improved treatment of ischemic stroke and could be a new approach for other central nervous system disorders.
#Stroke #Nanotechnology #MedicalBreakthrough
🔬 How it Works: The system uses a novel coating that helps it specifically target injured brain regions and then the energy-producing parts of cells (mitochondria). It also delivers drugs sequentially to restore cell function and manage inflammation.
🚀 Potential Impact: This intranasal delivery method shows promise for improved treatment of ischemic stroke and could be a new approach for other central nervous system disorders.
#Stroke #Nanotechnology #MedicalBreakthrough
Science News
Higher exposure to PM2.5 air pollution is associated with ~20% increased stroke risk, a study of 40,000+ participants found. Individuals in high-exposure areas had ~1.2× greater risk than those in lower exposure regions, even after adjusting for age, lifestyle…
• 🩺 A study in Thailand analyzed data from 77 provinces between 2014-2016, identifying 201,023 cases of acute ischemic stroke.
• 💨 The research found significant links between higher levels of PM 2.5 (fine particulate matter) and black carbon in the air, and increased numbers of acute ischemic stroke cases.
• 📉 PM 2.5 and black carbon were found to be associated with acute ischemic stroke cases with adjusted coefficients of 0.008 and 0.179, respectively (p<0.001 for both).
• 🌡️ Physical factors like temperature, wind speed, and income also showed associations with stroke cases, with lower temperatures and incomes, and higher wind speeds linked to more cases.
#AirPollution #Stroke #PublicHealth
• 💨 The research found significant links between higher levels of PM 2.5 (fine particulate matter) and black carbon in the air, and increased numbers of acute ischemic stroke cases.
• 📉 PM 2.5 and black carbon were found to be associated with acute ischemic stroke cases with adjusted coefficients of 0.008 and 0.179, respectively (p<0.001 for both).
• 🌡️ Physical factors like temperature, wind speed, and income also showed associations with stroke cases, with lower temperatures and incomes, and higher wind speeds linked to more cases.
#AirPollution #Stroke #PublicHealth
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Asundexian for Secondary Stroke Prevention (Masjuan, et al., 2026)
Read Full Article
#Stroke #StrokePrevention #ClinicalTrials
Read Full Article
#Stroke #StrokePrevention #ClinicalTrials
The New England Journal of Medicine
Asundexian for Secondary Stroke Prevention | NEJM
Patients with noncardioembolic ischemic stroke or transient ischemic attack (TIA)
are at risk for recurrent stroke. Low factor XI levels are associated with a reduced
risk of ischemic stroke. Asund...
are at risk for recurrent stroke. Low factor XI levels are associated with a reduced
risk of ischemic stroke. Asund...