The compelling need to provide adoptive cell therapy (ACT) to an increasing number of oncology patients within a meaningful therapeutic window makes the development of an efficient, fast, versatile, and safe genetic tool for creating recombinant T cells indispensable.…

Nature - The heterochromatin protein HP1 has an essential role in establishing several features of the 3D nuclear organization of the genome during early embryonic development in Drosophila.

A study shows that a substance in the drink kefir can help combat disease-causing, antibiotic resistant bacteria by disrupting their communication.

Cell and gene therapy (CGT) is an experimental space that has grown exponentially in recent years; the sector received nearly $20bn in funding last year, a 50% increase on the record $13.5bn it saw in 2018.

Inside your body, cell movement plays a crucial role in many significant biological processes, including wound healing, immune responses and the potential spread of cancer.

In this study, the monkey embryos containing human stem cells stayed alive and grew outside the body for a period of 19 days.

Disrupting a gene responsible for pigments allowed experts in Kobe, Japan to create albino opossum offspring.

Steroid-based inhalers deliver life-saving medication for millions of asthma sufferers, providing relief and the ability to simply breathe. Unfortunately, inhalers do not work for all patients, and with ...

Virus carrying corrective gene may have caused study participant’s bone marrow disorder

Cornell researchers have identified a new way to measure DNA torsional stiffness—how much resistance the helix offers when twisted—information that can potentially shed light on how cells work.

For the first time, researchers have developed a successful approach for identifying proteins inside different types of neurons in the brain of a living animal.

Membrane proteins are extracted from either human pluripotent stem cells or differentiated neurons and combined with lipids to synthesize biomimetic nanovesicles (NVs). Neural targeting of NVs can be...

Nature Communications - The phenotypic consequence of 3D genome boundary disruption on developmental processes remains insufficiently understood. Here, the authors show that perturbation of a SOX17...

The Google subsidiary solved a fundamental problem in biology but didn’t promptly share its solution. So a University of Washington team tried to re-create it.

Technique for editing bacterial genomes can record interactions between cells, may offer a way to edit genes in the human microbiome. Biological engineers at MIT have devised a new way to efficiently edit bacterial genomes and program memories into bacterial…

Nature Genetics - Cell-type-specific eQTL maps in the human kidney generated from the analysis of over 600 microdissected kidney samples, together with single-cell RNA sequencing and single-nucleus...