Q07- Thyroid hormone can cause which one of the following effects?
A- Hypoglycemia
B- Lowers blood cholesterol
C- Lowers body temperature
D- Lowers oxygen consumption

@PharmacyRxplus
@PharmacyRxplus

Q08- A 6-year-old boy with acute lymphoblastic leukemia develops cardiotoxicity after chemotherapy. Which drug is most likely responsible?
A-Cyclophosphamide
B-Doxorubicin
C-Methotrexate
D-Vincristine

@PharmacyRxplus
@PharmacyRxplus

Q09- A 58-year-old man takes verapamil for hypertension and angina. Which of the following is a common adverse effect of a high dose of this drug?
A- Constipation
B- Diarrhea
C- Hyperglycemia
D- Sexual dysfunction

@PharmacyRxplus
@PharmacyRxplus

Q10- An old man complains of progressive back pain and joint pain for 10 years. There is enlargement in the distal interphalangeal joints, osteophytes on the vertebral bodies, and sclerosis with narrowing of multiple joint spaces.
Which of the following is the most likely diagnosis?
A- Gout
B- Osteoarthritis
C- Osteomyelitis
D- Rheumatoid arthritis

@PharmacyRxplus
@PharmacyRxplus

Q11- Prolonged use of which one of the following medications can lead to increased metabolism of warfarin?
A-Meprobamate
B-Phenobarbital
C-Triazolam
D-Zolpidem

@PharmacyRxplus
@PharmacyRxplus

Q12- A 39-year-old man comes to the physician because of a 6-month history of progressive shortness of breath. He has had a cough productive of white sputum for 2 years. He smoked 1 pack of cigarettes daily for 16 years but quit 10 years ago. He is in mild respiratory distress with pursed lips and a barrel chest; he is using the accessory muscles of respiration. Breath sounds are distant and crackles are present in the lower lung fields bilaterally. Pulmonary function tests show a decreased FEV1:FVC ratio, increased residual volume, and decreased diffusion capacity. An x-ray of the chest shows hyperinflation and hypertranslucency of the lower lobes of both lungs. Which of the following is the most likely diagnosis?
(A) Asthma
(B) Bronchiectasis
(C) Chronic pulmonary fibrosis
(D) Cystic fibrosis
(E) Emphysema

@PharmacyRxplus
@PharmacyRxplus

Q13- A 67-year-old man with a history of chronic kidney disease presents with progressive shortness of breath and lower extremity edema. Echocardiography shows concentric left ventricular hypertrophy with normal ejection fraction. BNP is elevated.
Which of the following pathophysiologic mechanisms is most responsible for this patient’s condition?
A-Decreased myocardial contractility
B-Impaired ventricular relaxation
C-Increased preload due to valvular regurgitation
D-Reduced coronary perfusion

@PharmacyRxplus
@PharmacyRxplus

Q14- A patient with chronic kidney disease develops secondary hyperparathyroidism. Which of the following biochemical changes directly stimulates parathyroid hormone (PTH) secretion in this condition?
A-Decreased 1,25-dihydroxyvitamin D levels
B-Decreased serum phosphate
C-Increased calcium-sensing receptor activation
D-Increased intestinal calcium absorption

@PharmacyRxplus
@PharmacyRxplus

Q15- A patient taking allopurinol for gout should be closely monitored for which serious adverse effect?
A-Aplastic anemia
B-Hepatotoxicity
C-Severe hypersensitivity reaction
D-Thrombocytopenia

@PharmacyRxplus
@PharmacyRxplus

Q16- A 67-year-old man presents with sudden onset left arm weakness and facial droop that resolved completely within 30 minutes. CT scan of the head is normal.
What is the most likely diagnosis?
A-Intracerebral hemorrhage
B-Ischemic stroke
C-Subarachnoid hemorrhage
D-Transient ischemic attack

@PharmacyRxplus
@PharmacyRxplus

Q17- A patient treated with gentamicin develops renal impairment. What is the primary mechanism of this adverse effect?
A-Accumulation in proximal tubule cells
B-Acute interstitial nephritis
C-Decreased renal blood flow
D-Immune-mediated glomerulonephritis

@PharmacyRxplus
@PharmacyRxplus

Q18- A 24-year-old woman presents with neck swelling. Fine-needle aspiration of a thyroid nodule shows polygonal cells with amyloid deposits in the stroma.
Which hormone is most likely elevated in this patient?
A-Calcitonin
B-Parathyroid hormone
C-Thyroxine (T4)
D-Triiodothyronine (T3)

@PharmacyRxplus
@PharmacyRxplus

Q19- Which of the following antifungal medications inhibits ergosterol synthesis by blocking fungal cytochrome P450 enzymes?
A-Amphotericin B
B-Fluconazole
C-Flucytosine
D-Terbinafine

@PharmacyRxplus
@PharmacyRxplus

Q20- Which one of the following diuretics is appropriate to be prescribed for hypertension to a patient with a history of calcium oxalate renal stones?
A-Acetazolamide
B-Furosemide
C-Hydrochlorothiazide
D-Spironolactone

@PharmacyRxplus
@PharmacyRxplus

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