The Paternal Age Effect refers to the statistical association between older fathers and certain offspring health outcomes, e.g. genetic disorders.
The degree to which these associations are causal varies significantly between traits, and there is much debate on correlation vs. causation in academic literature on this topic.
For example, paternal age correlates with decreased offspring IQ, but this study found that the association almost disappears when controlling for genetic confounding (-2.6/+1.6 IQ points per decade rise in paternal age, averaging to -0.6).
For monogenic disorders associated with the PAE (which result from a single gene variant), an important causal mechanism is the accumulation of de novo mutations in sperm, approximately 1-2 per year of paternal age.
The majority of de novo mutations have little to no detectable impact on an individual's phenotype, but some can be harmful, others beneficial. Single nucleotide variants (dnSNVs), which affect a single DNA building block, are the most common form.
The most prevalent traits that are associated with the PAE, such as autism and schizophrenia, are highly polygenic (resulting from numerous gene variants). The contribution of a typical age-related dnSNV to such traits ranges from nonexistent to negligible, but some high-impact variants can contribute substantially.
(See, e.g. the papers listed in my most recent Tweet: https://x.com/thuletide_/status/2115218317636153554).
Classic (monogenic) PAE disorders are individually very rare, and the combined absolute risk of all known disorders in this category may be lower than the absolute risk of Down Syndrome alone (although, I haven't run this calculation).
Through advancements in technology and medicine, modern societies have significantly reduced (or even eliminated) the selection pressures that previously "purged" deleterious variants from the gene pool. As such, they now accumulate over time, contributing to mutational load: the population-scale reduction in fitness caused by the buildup of harmful mutations.
Mutational load stemming from relaxed selection pressures plausibly contributed to the rise of leftism over time, given that True Believer leftists are disproportionately genetic abominations.
In conclusion: while the PAE is unlikely to cause you any problems on an individual level due to the minuscule absolute risk factors, all high-IQ right-wing people should marry at age 18 and reproduce young to ensure the health of future generations. (Note: Teen marriage does not causally increase risk of divorce).
The degree to which these associations are causal varies significantly between traits, and there is much debate on correlation vs. causation in academic literature on this topic.
For example, paternal age correlates with decreased offspring IQ, but this study found that the association almost disappears when controlling for genetic confounding (-2.6/+1.6 IQ points per decade rise in paternal age, averaging to -0.6).
For monogenic disorders associated with the PAE (which result from a single gene variant), an important causal mechanism is the accumulation of de novo mutations in sperm, approximately 1-2 per year of paternal age.
The majority of de novo mutations have little to no detectable impact on an individual's phenotype, but some can be harmful, others beneficial. Single nucleotide variants (dnSNVs), which affect a single DNA building block, are the most common form.
The most prevalent traits that are associated with the PAE, such as autism and schizophrenia, are highly polygenic (resulting from numerous gene variants). The contribution of a typical age-related dnSNV to such traits ranges from nonexistent to negligible, but some high-impact variants can contribute substantially.
(See, e.g. the papers listed in my most recent Tweet: https://x.com/thuletide_/status/2115218317636153554).
Classic (monogenic) PAE disorders are individually very rare, and the combined absolute risk of all known disorders in this category may be lower than the absolute risk of Down Syndrome alone (although, I haven't run this calculation).
Through advancements in technology and medicine, modern societies have significantly reduced (or even eliminated) the selection pressures that previously "purged" deleterious variants from the gene pool. As such, they now accumulate over time, contributing to mutational load: the population-scale reduction in fitness caused by the buildup of harmful mutations.
Mutational load stemming from relaxed selection pressures plausibly contributed to the rise of leftism over time, given that True Believer leftists are disproportionately genetic abominations.
In conclusion: while the PAE is unlikely to cause you any problems on an individual level due to the minuscule absolute risk factors, all high-IQ right-wing people should marry at age 18 and reproduce young to ensure the health of future generations. (Note: Teen marriage does not causally increase risk of divorce).
This post was shadowbanned for some reason. If you are on Twitter, please check if you can see it.
https://x.com/thuletide_/status/2115203559851774310
https://x.com/thuletide_/status/2115203559851774310
X (formerly Twitter)
moonlight pepe (@thuletide_) on X
This thread is full of misrepresentation, lies, & hyperbole; e.g., her claim that geriatric pregnancies produce higher-IQ kids is flat-out wrong. The association is genetically confounded (she has…
The top 5 predictors of relationship satisfaction are:
1. Perceived partner commitment
2. Being appreciated
3. Sexual satisfaction
4. Perceived partner satisfaction
5. Conflict (or a lack thereof).
Source: Machine learning uncovers the most robust self-report predictors of relationship quality across 43 longitudinal couples studies (2020)
https://www.pnas.org/doi/epdf/10.1073/pnas.1917036117
1. Perceived partner commitment
2. Being appreciated
3. Sexual satisfaction
4. Perceived partner satisfaction
5. Conflict (or a lack thereof).
Source: Machine learning uncovers the most robust self-report predictors of relationship quality across 43 longitudinal couples studies (2020)
https://www.pnas.org/doi/epdf/10.1073/pnas.1917036117
MAGA voters:
- Sympathize more with Ukraine than Russia (50% vs. 5%).
- Consider Russia unfriendly or an enemy of America.
- Consider Ukraine to be friendly toward America.
- Think Zelensky wants to end the war.
- Overwhelmingly have a very unfavorable view of Putin.
- Sympathize more with Ukraine than Russia (50% vs. 5%).
- Consider Russia unfriendly or an enemy of America.
- Consider Ukraine to be friendly toward America.
- Think Zelensky wants to end the war.
- Overwhelmingly have a very unfavorable view of Putin.
"The Department of Homeland Security (DHS) is running one of the largest anti-left-wing surveillance operations in U.S. history, according to WIRED."
"President Donald Trump signed the memorandum in September 2025, following the assassination of right-wing activist Charlie Kirk."
https://www.wired.com/story/ice-is-running-one-of-the-largest-anti-left-surveillance-operations-in-us-history/
"President Donald Trump signed the memorandum in September 2025, following the assassination of right-wing activist Charlie Kirk."
https://www.wired.com/story/ice-is-running-one-of-the-largest-anti-left-surveillance-operations-in-us-history/
I was mass reported by feminists on Twitter so unfortunately I'm shadowbanned now.
I'll be crossposting my Tweets here for a while.
https://x.com/thuletide_/status/2115608478849130699
I'll be crossposting my Tweets here for a while.
https://x.com/thuletide_/status/2115608478849130699
X (formerly Twitter)
moonlight pepe (@thuletide_) on X
Percentage of women with tattoos in America:
Early 1990s ~1%
Early 2000s ~15%
Early 2010s ~23%
Early 2020s ~38%
Currently: ~40% of women aged 18-24 regret getting tattoos; ~60-80% of tattoo remov…
Early 1990s ~1%
Early 2000s ~15%
Early 2010s ~23%
Early 2020s ~38%
Currently: ~40% of women aged 18-24 regret getting tattoos; ~60-80% of tattoo remov…
Thuletide
I was mass reported by feminists on Twitter so unfortunately I'm shadowbanned now. I'll be crossposting my Tweets here for a while. https://x.com/thuletide_/status/2115608478849130699
I think, aesthetically, tattoos are passable for men who are capable of lethal violence, but they're completely unacceptable for all women, even gross fat hogs (they already look bad enough).
By "passable" I mean that they don't look completely wretched or incongruous, as they do on women.
However, tattoos are very bad for your health, so you shouldn't get them even if you're a stone-cold killer (as if any man of that disposition would take my advice).
By "passable" I mean that they don't look completely wretched or incongruous, as they do on women.
However, tattoos are very bad for your health, so you shouldn't get them even if you're a stone-cold killer (as if any man of that disposition would take my advice).
Telegram
Thuletide
Zero Hedge: "Study Finds Tattoo Ink Accumulates In Lymph Nodes"
People are waking up to the Tattoo Question.
Findings from the paper:
- White blood cells clear tattoo ink out of the skin (this is why tattoos fade over time), which then clogs up the lymphatic…
People are waking up to the Tattoo Question.
Findings from the paper:
- White blood cells clear tattoo ink out of the skin (this is why tattoos fade over time), which then clogs up the lymphatic…
Thuletide
"The Department of Homeland Security (DHS) is running one of the largest anti-left-wing surveillance operations in U.S. history, according to WIRED." "President Donald Trump signed the memorandum in September 2025, following the assassination of right-wing…
"Nothing of this scale has been seen in the United States, experts say, since the federal government’s counterinsurgency against the New Left and the anti-war movement in the 1960s and 1970s."