Genetically modified parasite successfully delivers drugs across the blood-brain barrier in mice, a potential new avenue for safely and effectively getting drugs to the human brain to treat neurological diseases
Read Full Article
#geneticmodification #parasitedelivery #bloodbrainbarrier #neurologicaltreatment #drugdelivery
Read Full Article
#geneticmodification #parasitedelivery #bloodbrainbarrier #neurologicaltreatment #drugdelivery
Fierce Biotech
Researchers engineer brain-infecting parasite into living drug delivery system
Toxoplasma gondii is a protozoan parasite famous for its cunning ways. | Toxoplasma gondii is a protozoan parasite famous for its cunning ways. This microbial manipulator can only reproduce inside of cats, so, if it finds itself in another mammalian host…
🔥2😱2👍1🖕1
Nanoplastics have the potential to cross the blood-brain barrier (BBB), suggests a new study using human BBB cells. The study demonstrated that both polystyrene and polyvinyl chloride (PVC) nanoplastics could cross the BBB, with PVC particles showing a higher penetration rate.
Read Full Article
#nanoplastics #bloodbrainbarrier #BBB #environmentalhealth #plasticpollution
Read Full Article
#nanoplastics #bloodbrainbarrier #BBB #environmentalhealth #plasticpollution
University of Eastern Finland
Pioneering study reveals nanoplastics have potential to cross blood-brain barrier
The research marks a significant advancement in understanding how nanoplastics might transfer in human blood and interact with biological systems.
😨3🤯1
Scientists engineer Toxoplasma parasites to carry therapeutic genes across blood-brain barrier
Read Full Article
#Toxoplasma #GeneTherapy #BloodBrainBarrier #Neuroscience #MedicalBreakthrough
Read Full Article
#Toxoplasma #GeneTherapy #BloodBrainBarrier #Neuroscience #MedicalBreakthrough
The Scientist
Genetically Engineered Parasites Smuggle Therapeutics into the Brain
Scientists modified Toxoplasma gondii to deliver a potential Rett Syndrome therapeutic to the mouse brain.
🔥3👾3👀1
Scientists discover new drug that prevents cognitive impairment in Alzheimer’s disease by directly protecting blood-brain barrier (BBB) 🧠💊. In mouse models treated with it, BBB stayed completely undamaged. Brains didn’t undergo neurodegeneration and cognition and memory were completely preserved. 🐭✨
Read Full Article
#AlzheimersResearch #CognitiveHealth #BloodBrainBarrier #Neurodegeneration #MedicalBreakthrough
Read Full Article
#AlzheimersResearch #CognitiveHealth #BloodBrainBarrier #Neurodegeneration #MedicalBreakthrough
The Daily
Potential new treatment for Alzheimer’s disease, other neurodegenerative conditions
Drug developed by Case Western Reserve University researchers found to protect ‘guardian of the brain’ Worldwide, more than 55 million people suffer from dementia caused by Alzheimer’s Disease (AD) and other conditions that destroy cells in the brain and…
Ultrasound technique can open the blood-brain barrier for drug delivery in brain cancer patients. 🧠💉 2/3 Children in a case study responded favorably to the treatment. 🌟👶
Read Full Article
#UltrasoundTherapy #BloodBrainBarrier #BrainCancer #PediatricCare #InnovativeTreatment
Read Full Article
#UltrasoundTherapy #BloodBrainBarrier #BrainCancer #PediatricCare #InnovativeTreatment
IEEE Spectrum
Ultrasound Opens New Front Against Lethal Brain Cancer in Kids
A new device uses ultrasound to open the blood-brain barrier, and it may allow drugs to better target deadly childhood brain tumors.
New study explains why cancer patients rarely get Alzheimer’s 🧠🔬: Tumors secrete a protein (Cystatin C) 🧬 that crosses the blood-brain barrier and dissolves amyloid plaques 🧪.
Read Full Article
#CancerAlzheimersLink #CystatinC #BloodBrainBarrier #AmyloidPlaques #Neurodegeneration
Read Full Article
#CancerAlzheimersLink #CystatinC #BloodBrainBarrier #AmyloidPlaques #Neurodegeneration
Nature
Cancer might protect against Alzheimer’s — this protein helps explain why
Nature - A molecule produced by cancer cells can shield the brain from Alzheimer’s disease in mice.
🤯2🤔1
Cannabis-derived cannabinoids may reduce neuroinflammation and oxidative stress. By acting on the endocannabinoid system (ECS), they may preserve blood–brain barrier integrity and limit neural damage in Alzheimer’s, Parkinson’s, multiple sclerosis and Huntington’s disease according to a review.
Read Full Article
#Cannabinoids #Neuroinflammation #EndocannabinoidSystem #BloodBrainBarrier #NeurodegenerativeDiseases
Read Full Article
#Cannabinoids #Neuroinflammation #EndocannabinoidSystem #BloodBrainBarrier #NeurodegenerativeDiseases
MDPI
Cannabinoids, the Blood–Brain Barrier, and Neurodegeneration: Mechanisms, Dysregulation, and Therapeutic Perspectives
Neurodegenerative diseases are a large and complex group of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, multiple sclerosis, and so on, which adversely affect the physical and mental health of millions…
Scientists find a mechanism for how exercise protects the brain: exercise-induced liver protein strengthens the blood-brain barrier, improving memory and slowing age-related decline
Read Full Article
#BrainHealth #ExerciseScience #BloodBrainBarrier #MemoryBoost #AgingResearch
Read Full Article
#BrainHealth #ExerciseScience #BloodBrainBarrier #MemoryBoost #AgingResearch
Scientists Find a Mechanism for How Exercise Protects the Brain | UC San Francisco
Scientists Find a Mechanism for How Exercise Protects the Brain
A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brain rejuvenation that many have been hunting for.
"Scientists just discovered that a high fat diet can cause gut bacteria to enter the brain".Live bacteria from the digestive system can travel directly into the brain when the intestinal barrier is weakened.
Read Full Article
#GutBrainAxis #DietAndMicrobiome #BloodBrainBarrier
Read Full Article
#GutBrainAxis #DietAndMicrobiome #BloodBrainBarrier
PsyPost
Scientists just discovered that a high-fat diet can cause gut bacteria to enter the brain
A high-fat diet can cause the intestinal lining to weaken, allowing live gut bacteria to travel directly to the brain in mice. Published in PLOS Biology, these findings suggest digestive health might directly influence human neurological conditions.
Sugar-coated nanoparticles cross the blood-brain barrier and shrink glioblastoma tumors in mice
Read Full Article
#NanoparticleTherapy #BloodBrainBarrier #GlioblastomaResearch
Read Full Article
#NanoparticleTherapy #BloodBrainBarrier #GlioblastomaResearch
ScienceAlert
Scientists Used Sugar to 'Trojan Horse' a Cancer Killer Into The Brain
A new hope for treatment.
❤1
Blood-Brain Barrier Successfully Repaired in Alzheimer's Models: in Alzheimer's disease, this protective border can begin to leak. The study used zebrafish, APOE4 mice, postmortem brain tissue and CSF from people with Alzheimer's, human cells, and three-dimensional blood-vessel models.
Read Full Article
#BloodBrainBarrier #AlzheimersResearch #Neurodegeneration
Read Full Article
#BloodBrainBarrier #AlzheimersResearch #Neurodegeneration
ScienceAlert
Blood-Brain Barrier Successfully Repaired in Alzheimer's Models
One step closer.