Researchers develop affordable, rapid blood test for brain cancer: Biochip that uses electrokinetic technology to detect biomarkers, or active Epidermal Growth Factor Receptors (EGFRs),which are overexpressed in certain cancers such as glioblastoma and found in extracellular vesicles.

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#BrainCancer #BiochipTechnology #EGFRs #Glioblastoma #BloodTest

Mobile phones are not linked to brain cancer, according to a major review of 28 years of research | The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A systematic review of human observational studies – Part I: Most researched outcomes

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#MobilePhones #BrainCancer #ResearchReview #RadiofrequencyFields #HumanObservationalStudies

China-US team creates plant-based nanoparticles to fight deadliest brain cancer | Scientists injected the nanoparticles into mice and observed that the particles successfully identified and attacked tumor cells.

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#ChinaUS #Nanoparticles #BrainCancer #PlantBased #MedicalBreakthrough

Glioblastoma (GBM) 🌟, an aggressive and fast-growing brain cancer 🧠, became smaller after dual-target CAR T-cell therapy 💉 in nearly two-thirds of patients. Several patients lived 12 months or longer 🗓️ after receiving the therapy, which is notable given the typical survival is less than a year.

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#Glioblastoma #CARTcelltherapy #BrainCancer #CancerResearch #PatientHope

Brain cancer cells can be ‘reprogrammed’ to stop them from spreading. 🧠🔬 By locking HA molecules in place so that they lose this flexibility, the researchers were able to ‘reprogramme’ glioblastoma cells so they stopped moving and were unable to invade surrounding tissue. 🛑🏥

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#BrainCancer #Glioblastoma #CancerResearch #CellReprogramming #HealthInnovation

Ultrasound technique can open the blood-brain barrier for drug delivery in brain cancer patients. 🧠💉 2/3 Children in a case study responded favorably to the treatment. 🌟👶

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#UltrasoundTherapy #BloodBrainBarrier #BrainCancer #PediatricCare #InnovativeTreatment

🔬 A new "Phenotype Analyzer Chip" device can detect how deadly brain tumors respond to treatment using just a blood test, offering a non-invasive alternative to surgery for monitoring glioblastoma.

🩸 This breakthrough, developed by Dr. Richard Lobb and Dr. Zhen Zhang at AIBN, analyzes tiny particles called extracellular vesicles in blood to provide fast and accurate information about brain cancer.

🧠 The technology, a collaboration with the Mark Hughes Foundation Centre for Brain Cancer Research, shows promise not only for brain cancer but also for monitoring other neurological conditions like Alzheimer's and Parkinson's.

#BrainCancer #MedicalBreakthrough #Neurology

🧠 Study finds individuals with Traumatic Brain Injury (TBI) are 1.75 times more likely to die from brain cancer than the general population.

💥 Those with TBI resulting from gunshot wounds showed over 14 times higher mortality risk from brain cancer. Mild but complicated TBI also carried nearly four times the risk.

📅 Research analyzed data from over 20,000 TBI patients in inpatient rehabilitation between 1987 and 2024.

#TBISurvivors #BrainCancer #HealthResearch

🧠 New Brain Cancer Vaccine Shows Promise in Clinical Trial
A peptide vaccine targeting a common genetic mutation in gliomas has shown remarkable results in a Phase 1 trial (NOA 16) involving 33 patients with high-grade astrocytomas.

📈 Significantly Improved Long-Term Survival
After up to eight years of follow-up, 66% of participants were still alive, with 42% showing no disease progression. This significantly exceeds previous median survival times of 2.5-5 years for aggressive tumor types.

🔬 Immune Response Linked to Better Outcomes
Patients whose immune systems responded strongly to the vaccine, activating T and B cells, had better long-term prognoses. Activated immune cells were observed migrating into tumors in patients with controlled disease.

💡 Potential for Standardized Immunotherapy
This vaccine targets a common mutation, allowing for a standardized approach unlike individual patient vaccines. Booster shots may prolong effectiveness without additional side effects.

#BrainCancer #Immunotherapy #ClinicalTrial

Glioma, a Type of Cancer that Hijacks Brain Activity to Fuel Its Growth. Scientists have uncovered one of the mechanisms in mice that makes this exploitation possible and believe the identification of this mechanism could create new opportunities for treatment.

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#GliomaResearch #BrainCancer #OncologyScience

🧠 Scientists have uncovered a mechanism gliomas use to exploit brain functions for growth.

🔬 A protein called neuroligin-3 (NLGN3) binds to CSPG4 on glioma cells, tightening the cell membrane and activating PIEZO1, a channel that signals for cell proliferation.

🐭 Glioma cells lacking PIEZO1 showed significantly less proliferation in mice, suggesting PIEZO1 is crucial for their growth.

💡 This mechanism is also present in healthy brain cells (OPCs), where it helps maintain a reserve of immature cells. Glioma cells appear to hijack this normal process.

#BrainCancer #Glioma #CancerResearch