Cancer biologists discover a new mechanism for an old drug: « Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations. »
Read Full Article
#CancerResearch #5Fluorouracil #DrugDiscovery #CancerBiology #PersonalizedMedicine
Read Full Article
#CancerResearch #5Fluorouracil #DrugDiscovery #CancerBiology #PersonalizedMedicine
MIT News
Cancer biologists discover a new mechanism for an old drug
Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but MIT researchers found that in certain cancers, it kills cells by interfering with RNA synthesis. The findings could help researchers design better…
🏆4
Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma 🧬🦠💔✨
Read Full Article
#TCellResearch #OvarianCancer #TRP53 #Immunotherapy #CancerBiology
Read Full Article
#TCellResearch #OvarianCancer #TRP53 #Immunotherapy #CancerBiology
Oncotarget
Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic…
https://doi.org/10.18632/oncotarget.28768 Jacob Haagsma, Yudith Ramos Valdes, Xuejin Ou, Rasheduzzaman Rashu, S.M. Mansour Haeryfar, Jim Petrik, Trevor G. Shepherd
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma | Science Advances
Read Full Article
#ImpairedNitrogenousWasteClearance #HepatocellularCarcinoma #LiverCancerResearch #ScienceAdvances #CancerBiology
Read Full Article
#ImpairedNitrogenousWasteClearance #HepatocellularCarcinoma #LiverCancerResearch #ScienceAdvances #CancerBiology
Science Advances
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma
Dietary protein restriction attenuates HCC growth.