A study shows that cancer cells can transfer their defective mitochondria to the body's immune cells and weaken them, thus evading the body's immune response.
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#CancerResearch #Immunology #Mitochondria #CancerCells #HealthScience
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#CancerResearch #Immunology #Mitochondria #CancerCells #HealthScience
Nature
Cancer cells ‘poison’ the immune system with tainted mitochondria
Nature - Immune cells lose their cancer-fighting prowess after taking tumours’ organelles on board.
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Researchers identify a previously unknown mechanism by which melanoma cancer cells paralyze immune cells through extracellular vesicle secretion, revealing a key strategy of immune evasion and offering new insights into potential immunotherapeutic targets for the deadliest form of skin cancer. 🦠🛡️💉✨
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#MelanomaResearch #Immunotherapy #CancerCells #ExtracellularVesicles #ImmuneEvasion
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#MelanomaResearch #Immunotherapy #CancerCells #ExtracellularVesicles #ImmuneEvasion
Cell
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion
Melanoma cells escape immune surveillance by releasing MHC-antigen-loaded large EVs,
known as melanosomes, that directly engage and impair CD8+ T cell receptors.
known as melanosomes, that directly engage and impair CD8+ T cell receptors.