Large-scale analysis of 15,836 ancient West Eurasians detects consistent trends in allele frequency change, showing many hundreds of alleles under strong directional selection the past 10,000 years, including variants that today predict complex traits such as body fat, schizophrenia, and cognition.
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#Genomics #PopulationGenetics #GWAS
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#Genomics #PopulationGenetics #GWAS
Nature
Ancient DNA reveals pervasive directional selection across West Eurasia
Nature - Analysis of 15,836 ancient West Eurasian genomes reveals hundreds of instances of directional selection, showing that sustained changes in allele frequency were widespread, rather than...