BMC Medicine - Intrusive memories of psychologically traumatic events bring distress both sub-clinically and clinically. This parallel-group, two-arm randomised controlled trial evaluated the...

Nature Communications - Here, the authors show a time-dependent shift from generalised cue associations to specific episodic coding of fearful memories. An overnight rebalancing between hippocampal...

Nature - In mice, stress altered the way that the brain formed memories, resulting in an unnecessary fear response.

Nature - Two brain regions work together when mice learn to override the instinct to run and hide from a potential threat.

Nature - A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

Researchers analyzing blood samples discovered that the biological mechanisms driving PTSD vary by sex, potentially explaining why some drug trials have failed to help female patients.

A new longitudinal analysis suggests that specific PTSD symptoms, particularly hyperarousal, drive hazardous drinking in military reservists. The findings indicate that male soldiers are uniquely at risk for alcohol problems stemming from physiological agitation.