A new study finds no evidence of T cell exhaustion after multiple SARS-CoV-2 mRNA vaccinations 💉 – even in frail older adults 👵👴 and immunosuppressed individuals 🤒.
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#SARSCoV2 #mRNAVaccine #TCellImmunity #HealthResearch #VaccinationScience
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#SARSCoV2 #mRNAVaccine #TCellImmunity #HealthResearch #VaccinationScience
Nature
No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations
Nature Communications - Repeated vaccination is needed to maintain high levels of SARS-CoV-2 immunity in vulnerable populations, but there is concern that it could lead to immune exhaustion. Here,...
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Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells | Nature Immunology
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#EndothelialImmunity #NOD2Signaling #TCellImmunity
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#EndothelialImmunity #NOD2Signaling #TCellImmunity
Nature
Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory…
Nature Immunology - Tsankov and colleagues find that NOD2 signaling in intestinal endothelial cells drives T cell homing to the mesenteric lymph nodes during homeostasis and infection.