These results support larger cross sectional findings indicating that mild Wildtype
SARS-CoV-2 infection can be followed by small changes in cognition and memory that
persist for at least a year. The mechanistic basis and clinical implications of these
small…

Nature Medicine - The rapid waning of SARS-CoV-2-specific serum antibodies observed after immunization with COVID-19 mRNA vaccines may be accounted for by the absence of long-lived plasma cells in...

In 2021, NIH launched the Researching COVID to Enhance Recovery (RECOVER) Initiative, a nationwide research program, to fully understand, diagnose, and treat Long COVID. We continue to learn more a…

Researchers have discovered an alternative pathway for how viruses, including SARS-CoV-2 enter host cells, offering new potential treatment modalities.

The peptide, which is a short chain of amino acids, has shown effectiveness in experiments involving various coronavirus strains.

A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the SARS-CoV-2 virus that causes COVID-19, raising the possibility that it could someday spread to humans, Chinese researchers have reported. The virus…

A multi-institutional study co-led by Weill Cornell Medicine finds that pregnancy may offer some protection from developing Long COVID— a condition lasting for months after a person recovers from SARS-CoV-2 infection.

Therapeutic monoclonal antibodies can prevent severe disease in SARS-CoV-2 exposed individuals. However, currently circulating virus variants have evolved to gain significant resistance to nearly all neutralizing human immune system-derived therapeutic monoclonal…

Nature Communications - Repeated vaccination is needed to maintain high levels of SARS-CoV-2 immunity in vulnerable populations, but there is concern that it could lead to immune exhaustion. Here,...

The soluble S1 subunit of Spike protein (SP) from the SARS‐CoV-2 of different variants of concern (VOCs) may directly bind and activate human NK cells in vit...

SARS-CoV-2 induces amyloid-β pathology in the central nervous system.

“Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports

Mycoplasma pneumoniae is a bacterial infection not known to…

Immune escape by SARS-CoV-2 emerging variants jeopardizes vaccine effectiveness, necessitating new immunization strategies. Here, we assessed the antibody B-cell response in 40 individuals receiving ...

Background: The efficacy of a single oral dose of Ivermectin as prophylaxis for SARS-CoV-2 is uncertain. This trial sought to evaluate the effectiveness of a single oral low dose of Ivermectin to prevent SARS-CoV-2 infection or reduce symptoms if infection…

Scientific Reports - The coronaviral landscape across diverse mammalian species in the Northeastern United States

Nature Communications - Newly emerging SARS-CoV-2 variants underscore the need for broad-spectrum antiviral solutions. This study shows a macrocyclic peptide inhibitor that locks the SARS-CoV-2...

npj Vaccines - A single-dose amber codon carrying live attenuated vaccine elicits pan-sarbecovirus immunity and blocks SARS-CoV-2 transmission

People who recovered from COVID-19 infection or were vaccinated against SARS-CoV-2 are more likely to have immunity to other closely related bat coronaviruses that could have the potential to threaten future human health.