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Endocannabinoids produced by the body may contribute to the "runner's high": the happiness, calm, reduced anxiety, and dulled pain some people experience during long runs. This feeling was once credited to endorphins, but they do not readily cross the barrier between the blood and brain.

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Endocannabinoids produced by the body may contribute to the "runner's high": the happiness, calm, reduced anxiety, and dulled pain some people experience during long runs. This feeling was once credited to endorphins, but they do not readily cross the barrier…
🏃‍♂️ New research in BMC Medicine investigates how the body's natural "cannabis-like" chemicals, endocannabinoids, respond to prolonged exercise.

🩸 In a marathon study, levels of anandamide, linked to bliss, increased significantly from 8.7 miles onward, while 2-AG, associated with recovery, rose near the finish and post-race.

ultramarathon runners (100-230 km), endocannabinoid levels also increased, but surprisingly, not always higher than after a standard marathon. Exercise intensity may be more critical than duration for these chemical responses.

🤔 The "runner's high" remains elusive; elevated endocannabinoids alone don't guarantee it, and factors like extreme fatigue, pain, and individual experience play a complex role.

#runnershigh #endurance #science