What is SWAYATT?
SWAYATT (Startups, Women & Youth Advantage Through e-Transactions) is an initiative of the Government e-Marketplace launched in February 2019 to promote inclusive participation in public procurement. The initiative focuses on enabling startups, women entrepreneurs, youth, Micro & Small Enterprises (MSEs), Self-Help Groups (SHGs), and marginalized communities to access government markets. SWAYATT aims to remove entry barriers and enhance ease of doing business for these groups on the GeM platform
SWAYATT (Startups, Women & Youth Advantage Through e-Transactions) is an initiative of the Government e-Marketplace launched in February 2019 to promote inclusive participation in public procurement. The initiative focuses on enabling startups, women entrepreneurs, youth, Micro & Small Enterprises (MSEs), Self-Help Groups (SHGs), and marginalized communities to access government markets. SWAYATT aims to remove entry barriers and enhance ease of doing business for these groups on the GeM platform
What is GeM?
Government e Marketplace (GeM) is an online platform that facilitates end-to-end procurement of goods and services by various Central/State Ministries, departments, organizations, public sector undertakings, Panchayats and Cooperatives. GeM, launched in 2016 under the vision of βMinimum Government, Maximum Governance,β is a paperless, cashless and contactless platform enabling Government buyers to directly procure goods and services from pan-India sellers online
Government e Marketplace (GeM) is an online platform that facilitates end-to-end procurement of goods and services by various Central/State Ministries, departments, organizations, public sector undertakings, Panchayats and Cooperatives. GeM, launched in 2016 under the vision of βMinimum Government, Maximum Governance,β is a paperless, cashless and contactless platform enabling Government buyers to directly procure goods and services from pan-India sellers online
β€4π1
π Buddhist Sangha (Monastic Order)
π Community Structure
β Organized group of monks (bhikkhus) & nuns (bhikkhunis)
π Notable Figure
β Mahapajapati Gotami β First woman to join the Sangha
π Textual Source
β Vinaya Pitaka β Contains monastic rules
π Community Structure
β Organized group of monks (bhikkhus) & nuns (bhikkhunis)
π Notable Figure
β Mahapajapati Gotami β First woman to join the Sangha
π Textual Source
β Vinaya Pitaka β Contains monastic rules
β€3
π Ajivika Philosophy β Key Idea Only
π Founder
β Makkhali Gosala
π Core Belief System
β Strict determinism β belief in destiny (Niyati)
β Rejects karma β everything is preordained, no role of karma in liberation
π Path to Salvation
β Liberation is automatic through cycles of rebirth, no conscious effort required
π Founder
β Makkhali Gosala
π Core Belief System
β Strict determinism β belief in destiny (Niyati)
β Rejects karma β everything is preordained, no role of karma in liberation
π Path to Salvation
β Liberation is automatic through cycles of rebirth, no conscious effort required
β€4
π Mirabai (1498β1546 CE)
π Early Life
β Born in Merta
β Married to Bhoj Raj, son of Rana Sanga of Mewar
β Renounced royal life to live as a wandering devotee of Krishna
π Bhakti & Philosophy
β Leading female saint-poet of the Bhakti movement
β Advocate of Saguna Bhakti (devotion to a personal God)
β Composed devotional songs expressing intense love for Krishna
β Famous work: Rag-Govind
π Social Message
β Disciple of Raidas
β Rejected caste hierarchy and social orthodoxy
β Spiritual equality over ritualism
π Legacy
β Songs widely sung in Rajasthan and Gujarat
β Popular among marginalised and underprivileged communities
β Symbol of devotion, courage, and social defiance
#history #prelims #mains
Join https://t.me/CSE_EXAM https://t.me/Upsc_4_history
π Early Life
β Born in Merta
β Married to Bhoj Raj, son of Rana Sanga of Mewar
β Renounced royal life to live as a wandering devotee of Krishna
π Bhakti & Philosophy
β Leading female saint-poet of the Bhakti movement
β Advocate of Saguna Bhakti (devotion to a personal God)
β Composed devotional songs expressing intense love for Krishna
β Famous work: Rag-Govind
π Social Message
β Disciple of Raidas
β Rejected caste hierarchy and social orthodoxy
β Spiritual equality over ritualism
π Legacy
β Songs widely sung in Rajasthan and Gujarat
β Popular among marginalised and underprivileged communities
β Symbol of devotion, courage, and social defiance
#history #prelims #mains
Join https://t.me/CSE_EXAM https://t.me/Upsc_4_history
β€4
Itβs official now, as per the proposed βThe Constitution (One Hundred and Thirty First Amendment) Bill, 2026, strength of Lok Sabha increased from 543 to 850 members....
β€13π3π₯1
Parliamentary committees PYQ THEMES
Upsc prelims accelerator
100+ MCQ /Day
Practice is key clear prelims
Total - 4000+ MCQ
Fee- 499699
Join CLICK HERE
Upsc prelims accelerator
100+ MCQ /Day
Practice is key clear prelims
Total - 4000+ MCQ
Fee- 499
Join CLICK HERE
β€3
π BHASKAR Initiative
π Full Form
β BHASKAR stands for Bharat Startup Knowledge Access Registry.
π Launch
β Launched in 2024 under the Startup India programme.
π Aim
β To build the worldβs largest digital registry of stakeholders in Indiaβs startup ecosystem.
β To strengthen collaboration among startups, investors, incubators, mentors and policymakers.
π Implemented By
β Implemented by the Department for Promotion of Industry and Internal Trade under the Ministry of Commerce and Industry.
π Significance
β Provides a one-stop digital platform to centralize and streamline data related to the startup ecosystem.
β Facilitates better networking and collaboration among different stakeholders.
β Supports evidence-based policymaking for Startup India.
β Helps in identifying trends, funding gaps and sector-wise opportunities in the startup ecosystem.
#goverment_schemes
Join https://t.me/PIB_UPSC
https://t.me/upsc_government_scheme
π Full Form
β BHASKAR stands for Bharat Startup Knowledge Access Registry.
π Launch
β Launched in 2024 under the Startup India programme.
π Aim
β To build the worldβs largest digital registry of stakeholders in Indiaβs startup ecosystem.
β To strengthen collaboration among startups, investors, incubators, mentors and policymakers.
π Implemented By
β Implemented by the Department for Promotion of Industry and Internal Trade under the Ministry of Commerce and Industry.
π Significance
β Provides a one-stop digital platform to centralize and streamline data related to the startup ecosystem.
β Facilitates better networking and collaboration among different stakeholders.
β Supports evidence-based policymaking for Startup India.
β Helps in identifying trends, funding gaps and sector-wise opportunities in the startup ecosystem.
#goverment_schemes
Join https://t.me/PIB_UPSC
https://t.me/upsc_government_scheme
β€6
π Adichanallur Archaeological Site
π Location
β Situated in Thoothukudi district on the banks of the Thamirabarani River near the ancient port town of Korkai.
β It is one of the oldest Iron Age archaeological sites in India.
π Interlinkage with Korkai
β The site likely prospered due to its proximity to Korkai, a major maritime trade centre mentioned in Sangam literature.
π Timeline
β A 2019 study dated artefacts from the site between 905 BCE and 696 BCE.
β Thus, the site is older than Keezhadi.
π Evidence
β Skeletal remains discovered at the site show multiracial traits.
β This indicates that Adichanallur may have been a cosmopolitan settlement with diverse communities.
π Major Findings
β Extensive urn burials
β Skeletal remains
β Bronze artefacts
β Early cultural evidence of South India
π Other Important Iron Age Sites in India
β Sivagalai
β Mayiladumparai
β Brahmagiri
β Gachibowli
β Hallur
β Paiyampalli
β Malhar
β Atranjikhera
#prelims
#art_and_culture
https://t.me/Studytoday1
https://t.me/upsc_art_and_culture
π Location
β Situated in Thoothukudi district on the banks of the Thamirabarani River near the ancient port town of Korkai.
β It is one of the oldest Iron Age archaeological sites in India.
π Interlinkage with Korkai
β The site likely prospered due to its proximity to Korkai, a major maritime trade centre mentioned in Sangam literature.
π Timeline
β A 2019 study dated artefacts from the site between 905 BCE and 696 BCE.
β Thus, the site is older than Keezhadi.
π Evidence
β Skeletal remains discovered at the site show multiracial traits.
β This indicates that Adichanallur may have been a cosmopolitan settlement with diverse communities.
π Major Findings
β Extensive urn burials
β Skeletal remains
β Bronze artefacts
β Early cultural evidence of South India
π Other Important Iron Age Sites in India
β Sivagalai
β Mayiladumparai
β Brahmagiri
β Gachibowli
β Hallur
β Paiyampalli
β Malhar
β Atranjikhera
#prelims
#art_and_culture
https://t.me/Studytoday1
https://t.me/upsc_art_and_culture
β€6π1
Day 118: 15 April target:
Economy: REVISION
Topics -
Revision &
PYQs
Current Affairs: December 2025, January February March 2026
Revision
#UpscRevisionProgram
After completion of target post 'DONE'
In comment section. Targets are decided as per practical approach. In remaining time, you can study whatever you want.
Thank you.
@upsc_answer_written
@CSE_EXAM
Economy: REVISION
Topics -
Revision &
PYQs
Current Affairs: December 2025, January February March 2026
Revision
#UpscRevisionProgram
After completion of target post 'DONE'
In comment section. Targets are decided as per practical approach. In remaining time, you can study whatever you want.
Thank you.
@upsc_answer_written
@CSE_EXAM
β€1
#Goodmorning
β³39 days left CSP26[ 24-05-26]
β³128 days left CSM26 [ 21-08-26]
β³235 days left UPPSC prelims 6 December
β³102 days left 72nd BPSC PRELIMS 26 July
β³95 days left CAPF AC 19 July
β³81 days left UKPSC PRELIMS 5 July
β³54 days Left OPSC/ GPSC prelims 07 June
β³47 days left MPSC (MH) prelims [ 31-05-26]
β³11 days Left MPPSC (MP)/HCS Prelims 26 April
β³10 days Left bpsc mains 25 April
JPSC PRELIMS 19 April
#Target
#TargetOnlyone
#Accountability
https://t.me/anmolvachan1
β³39 days left CSP26[ 24-05-26]
β³128 days left CSM26 [ 21-08-26]
β³235 days left UPPSC prelims 6 December
β³102 days left 72nd BPSC PRELIMS 26 July
β³95 days left CAPF AC 19 July
β³81 days left UKPSC PRELIMS 5 July
β³54 days Left OPSC/ GPSC prelims 07 June
β³47 days left MPSC (MH) prelims [ 31-05-26]
β³11 days Left MPPSC (MP)/HCS Prelims 26 April
β³10 days Left bpsc mains 25 April
JPSC PRELIMS 19 April
#Target
#TargetOnlyone
#Accountability
https://t.me/anmolvachan1
π CURRENT AFFAIRS β 14 APRIL 2026
π INTERNATIONAL
π UK Pauses Transfer of Chagos Islands
β United Kingdom pauses plan to transfer sovereignty of Chagos Islands to Mauritius
β Decision taken after opposition from United States
β US President Donald Trump criticised transfer, citing strategic concerns
π About Chagos Islands
β Located in central Indian Ocean, south of Maldives
β Includes strategically important island Diego Garcia
β Diego Garcia hosts major joint UKβUS military base
β Under proposed 2025 deal, UK would lease Diego Garcia back for 99 years after transfer to Mauritius
π ICJ Advisory Opinion
β International Court of Justice in 2019 asked UK to unconditionally withdraw from Chagos Islands and supported Mauritiusβ claim
π NATIONAL
π Project Cheetah Achieves Major Milestone
β Female cheetah Nirva gives birth to 4 cubs at Kuno National Park
β These are first successful βMade in Indiaβ cheetah cubs under Project Cheetah
β Nirva was among cheetahs brought from Africa
π About Project Cheetah
β Launched in 2022
β Worldβs first intercontinental large wild carnivore translocation project
β Works under Project Tiger
π Cheetah Imports So Far
β 8 cheetahs from Namibia in 2022
β 12 cheetahs from South Africa in 2023
β 9 cheetahs from Botswana in 2026
β All released in Kuno National Park, Madhya Pradesh
β Implemented by National Tiger Conservation Authority under Ministry of Environment
π Supreme Court Clarifies Right to Vote
β Supreme Court of India rules that right to vote and right to contest elections are not Fundamental Rights
β They are statutory rights created by laws of Parliament and State Legislatures
β Judgment delivered in case related to cooperative society elections in Rajasthan
π Key Points
β Right to vote allows participation in elections
β Right to contest can be restricted through eligibility conditions
β Neither is included under Part III of Constitution
π Patent Filings Rise to Historic High
β India records 1,43,729 patent applications in FY 2025β26
β Increase of 30.2% over previous year
β India becomes worldβs 6th largest patent filer
β More than 69% applications filed by domestic applicants
π Leading States
β Tamil Nadu
β Karnataka
β Maharashtra
π Patent Validity
β Patent: 20 years
β Trademark: 10 years
β Design: 10 years + extendable by 5 years
β Copyright: Lifetime of author + 60 years
π Retail Inflation Rises to 13-Month High
β Indiaβs retail inflation rises to 3.4% in March 2026 from 3.2% in February
β Highest level in 13 months
β Main reasons:
β‘ Rise in LPG prices
β‘ Increase in vegetable prices
β‘ West Asia conflict raising energy costs
β Food inflation rises to 3.87% in March from 3.47% in February
π Startup India Fund of Funds 2.0 Notified
β Government notifies Startup India Fund of Funds 2.0 with corpus of βΉ10,000 crore
β Aim: boost capital flow to startups through Alternative Investment Funds (AIFs)
β Priority sectors include deep tech, AI, robotics and advanced technologies
β Implemented by Small Industries Development Bank of India
β Guidelines issued by DPIIT
π e-SafeHER Cyber Security Programme
β Centre for Development of Advanced Computing Hyderabad and Reliance Foundation launch e-SafeHER programme
β Target: 1 million rural women
β Objective: promote cyber awareness and safe digital practices
π Key Feature
β Women will be trained as βCyber Sakhisβ
β Target: 1 million Cyber Sakhis by 2029
π DEFENCE
π Indian Army Launches βSamudra Sahasβ
β Indian Army flags off its first blue-water sailing expedition βSamudra Sahasβ from Marve
β Expedition is part of Regiment of Artillery bicentenary celebrations
π Expedition Details
β Total distance: 520 nautical miles
β Route: Mumbai β Vijaydurg β Goa β Mumbai
β Conducted in 4 legs using 21-foot Seabird class sailing boats
β Supported by Indian Navy and Indian Coast Guard
π NCC Launches Cyber Security Capacity Programme
β National Cadet Corps partners with National Institute of Electronics and Information Technology
β Launches nationwide Cyber Security Capacity Building Programme for NCC cadets
π INTERNATIONAL
π UK Pauses Transfer of Chagos Islands
β United Kingdom pauses plan to transfer sovereignty of Chagos Islands to Mauritius
β Decision taken after opposition from United States
β US President Donald Trump criticised transfer, citing strategic concerns
π About Chagos Islands
β Located in central Indian Ocean, south of Maldives
β Includes strategically important island Diego Garcia
β Diego Garcia hosts major joint UKβUS military base
β Under proposed 2025 deal, UK would lease Diego Garcia back for 99 years after transfer to Mauritius
π ICJ Advisory Opinion
β International Court of Justice in 2019 asked UK to unconditionally withdraw from Chagos Islands and supported Mauritiusβ claim
π NATIONAL
π Project Cheetah Achieves Major Milestone
β Female cheetah Nirva gives birth to 4 cubs at Kuno National Park
β These are first successful βMade in Indiaβ cheetah cubs under Project Cheetah
β Nirva was among cheetahs brought from Africa
π About Project Cheetah
β Launched in 2022
β Worldβs first intercontinental large wild carnivore translocation project
β Works under Project Tiger
π Cheetah Imports So Far
β 8 cheetahs from Namibia in 2022
β 12 cheetahs from South Africa in 2023
β 9 cheetahs from Botswana in 2026
β All released in Kuno National Park, Madhya Pradesh
β Implemented by National Tiger Conservation Authority under Ministry of Environment
π Supreme Court Clarifies Right to Vote
β Supreme Court of India rules that right to vote and right to contest elections are not Fundamental Rights
β They are statutory rights created by laws of Parliament and State Legislatures
β Judgment delivered in case related to cooperative society elections in Rajasthan
π Key Points
β Right to vote allows participation in elections
β Right to contest can be restricted through eligibility conditions
β Neither is included under Part III of Constitution
π Patent Filings Rise to Historic High
β India records 1,43,729 patent applications in FY 2025β26
β Increase of 30.2% over previous year
β India becomes worldβs 6th largest patent filer
β More than 69% applications filed by domestic applicants
π Leading States
β Tamil Nadu
β Karnataka
β Maharashtra
π Patent Validity
β Patent: 20 years
β Trademark: 10 years
β Design: 10 years + extendable by 5 years
β Copyright: Lifetime of author + 60 years
π Retail Inflation Rises to 13-Month High
β Indiaβs retail inflation rises to 3.4% in March 2026 from 3.2% in February
β Highest level in 13 months
β Main reasons:
β‘ Rise in LPG prices
β‘ Increase in vegetable prices
β‘ West Asia conflict raising energy costs
β Food inflation rises to 3.87% in March from 3.47% in February
π Startup India Fund of Funds 2.0 Notified
β Government notifies Startup India Fund of Funds 2.0 with corpus of βΉ10,000 crore
β Aim: boost capital flow to startups through Alternative Investment Funds (AIFs)
β Priority sectors include deep tech, AI, robotics and advanced technologies
β Implemented by Small Industries Development Bank of India
β Guidelines issued by DPIIT
π e-SafeHER Cyber Security Programme
β Centre for Development of Advanced Computing Hyderabad and Reliance Foundation launch e-SafeHER programme
β Target: 1 million rural women
β Objective: promote cyber awareness and safe digital practices
π Key Feature
β Women will be trained as βCyber Sakhisβ
β Target: 1 million Cyber Sakhis by 2029
π DEFENCE
π Indian Army Launches βSamudra Sahasβ
β Indian Army flags off its first blue-water sailing expedition βSamudra Sahasβ from Marve
β Expedition is part of Regiment of Artillery bicentenary celebrations
π Expedition Details
β Total distance: 520 nautical miles
β Route: Mumbai β Vijaydurg β Goa β Mumbai
β Conducted in 4 legs using 21-foot Seabird class sailing boats
β Supported by Indian Navy and Indian Coast Guard
π NCC Launches Cyber Security Capacity Programme
β National Cadet Corps partners with National Institute of Electronics and Information Technology
β Launches nationwide Cyber Security Capacity Building Programme for NCC cadets
β€4
β
Aim: train cadets in cyber awareness, digital hygiene and cyber defence skills
β Supports Digital India and National Skills Qualification Framework
π STATES
π Gaganyaan Mission
β Indiaβs human spaceflight programme led by ISRO
β Aim: send Indian astronauts to Low Earth Orbit and bring them back safely
β India will become 4th country after US, Russia and China to send humans into space
β ISRO also plans to build Indiaβs own space station by 2028
π IMPORTANT DAYS
π 107th Anniversary of Jallianwala Bagh Massacre
β Nation observes 107th anniversary of Jallianwala Bagh Massacre on 13 April
β British troops fired on unarmed civilians gathered in Amritsar in 1919
β Incident occurred in backdrop of the Rowlatt Act, 1919
β Rowlatt Act allowed arrest without trial and detention up to 2 years
π 136th Birth Anniversary of Dr. B.R. Ambedkar
β Nation celebrates 136th birth anniversary of B. R. Ambedkar on 14 April
β Born on 14 April 1891
β Known as chief architect of Indian Constitution
β Awarded Bharat Ratna posthumously in 1990
π Siachen Day
β Siachen Day observed on 13 April
β Marks launch of Operation Meghdoot in 1984
β Indian Army and Indian Air Force pay tribute to soldiers guarding Siachen Glacier, the worldβs highest battlefield
π SPORTS
π Sawan Barwal Breaks 47-Year-Old Marathon Record
β Sawan Barwal breaks Indiaβs oldest national athletics record at Rotterdam Marathon 2026
β Timing: 2:11:58
β Breaks 47-year-old record of Shivnath Singh set in 1978
β Sawan Barwal finished 20th in his debut marathon
#CurrentAffairs
β Supports Digital India and National Skills Qualification Framework
π STATES
π Gaganyaan Mission
β Indiaβs human spaceflight programme led by ISRO
β Aim: send Indian astronauts to Low Earth Orbit and bring them back safely
β India will become 4th country after US, Russia and China to send humans into space
β ISRO also plans to build Indiaβs own space station by 2028
π IMPORTANT DAYS
π 107th Anniversary of Jallianwala Bagh Massacre
β Nation observes 107th anniversary of Jallianwala Bagh Massacre on 13 April
β British troops fired on unarmed civilians gathered in Amritsar in 1919
β Incident occurred in backdrop of the Rowlatt Act, 1919
β Rowlatt Act allowed arrest without trial and detention up to 2 years
π 136th Birth Anniversary of Dr. B.R. Ambedkar
β Nation celebrates 136th birth anniversary of B. R. Ambedkar on 14 April
β Born on 14 April 1891
β Known as chief architect of Indian Constitution
β Awarded Bharat Ratna posthumously in 1990
π Siachen Day
β Siachen Day observed on 13 April
β Marks launch of Operation Meghdoot in 1984
β Indian Army and Indian Air Force pay tribute to soldiers guarding Siachen Glacier, the worldβs highest battlefield
π SPORTS
π Sawan Barwal Breaks 47-Year-Old Marathon Record
β Sawan Barwal breaks Indiaβs oldest national athletics record at Rotterdam Marathon 2026
β Timing: 2:11:58
β Breaks 47-year-old record of Shivnath Singh set in 1978
β Sawan Barwal finished 20th in his debut marathon
#CurrentAffairs
β€1β€βπ₯1
INDICES & REPORTS (1).pdf
836.2 KB
Compilation of Major Reports and Indices and their key findings that can be asked in Prelims 26.
Must Know all the reports published by WEF, IMF, NITI Ayog, WTO, RBI, UNEP, IPCC to eliminate options.
Must Know all the reports published by WEF, IMF, NITI Ayog, WTO, RBI, UNEP, IPCC to eliminate options.
β€3π2
Parliamentary committees PYQ THEMES
Upsc prelims accelerator
100+ MCQ /Day
Practice is key clear prelims
Total - 4000+ MCQ
Fee- 499699
Join CLICK HERE
Upsc prelims accelerator
100+ MCQ /Day
Practice is key clear prelims
Total - 4000+ MCQ
Fee- 499
Join CLICK HERE
β€1
π Tuberculosis (TB)
β Caused by: Tuberculosis is caused by Mycobacterium tuberculosis.
π Transmission
β Airborne disease; spreads when an infected person coughs, sneezes or spits.
β Infection occurs through inhalation of droplet nuclei.
π Affected System
β Primarily affects the lungs (Pulmonary TB).
β Can also affect kidneys, brain, spine etc. in Extra-Pulmonary TB (EPTB).
π Treatment
β Curable with antibiotics.
β Latent TB and active TB require different treatment approaches.
β New BPaLM regimen approved in 2024 under Indiaβs MDR-TB programme.
β BCG vaccine is the only licensed TB vaccine.
π Recent Developments
β MTBVAC became the first vaccine candidate derived from a human source to enter clinical trials in India in 2024.
β Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) is being tested for early diagnosis.
β AI-based chest X-ray interpretation tool βDeepCXRβ is being used under the National TB Elimination Programme.
β According to the 2025 WHO Global TB Report, Indiaβs TB incidence declined by 21% between 2015 and 2024.
π Trachoma
β Caused by: Trachoma is caused by Chlamydia trachomatis bacteria.
π Transmission
β Spreads through direct or indirect contact with eye, nose or throat secretions of infected persons.
π Affected System
β Affects the eyes and can cause irreversible blindness.
π Treatment
β WHO-recommended SAFE strategy:
β‘οΈ Surgery
β‘οΈ Antibiotics (especially azithromycin and tetracycline)
β‘οΈ Facial cleanliness
β‘οΈ Environmental improvement
π Key Features
β It is a Neglected Tropical Disease (NTD).
β In 2024, India received a Certificate of Elimination of Trachoma from the World Health Organization at the 78th World Health Assembly in Geneva.
β India became the third country in the WHO South-East Asia Region after Nepal and Myanmar to eliminate trachoma.
β Earlier, India had eliminated Guinea Worm Disease in 2000 and Yaws in 2016.
#GS3
#prelims
#science_technology
#science_and_technology
Join https://t.me/PIB_UPSC
https://t.me/upsc_science_and_technology
β Caused by: Tuberculosis is caused by Mycobacterium tuberculosis.
π Transmission
β Airborne disease; spreads when an infected person coughs, sneezes or spits.
β Infection occurs through inhalation of droplet nuclei.
π Affected System
β Primarily affects the lungs (Pulmonary TB).
β Can also affect kidneys, brain, spine etc. in Extra-Pulmonary TB (EPTB).
π Treatment
β Curable with antibiotics.
β Latent TB and active TB require different treatment approaches.
β New BPaLM regimen approved in 2024 under Indiaβs MDR-TB programme.
β BCG vaccine is the only licensed TB vaccine.
π Recent Developments
β MTBVAC became the first vaccine candidate derived from a human source to enter clinical trials in India in 2024.
β Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) is being tested for early diagnosis.
β AI-based chest X-ray interpretation tool βDeepCXRβ is being used under the National TB Elimination Programme.
β According to the 2025 WHO Global TB Report, Indiaβs TB incidence declined by 21% between 2015 and 2024.
π Trachoma
β Caused by: Trachoma is caused by Chlamydia trachomatis bacteria.
π Transmission
β Spreads through direct or indirect contact with eye, nose or throat secretions of infected persons.
π Affected System
β Affects the eyes and can cause irreversible blindness.
π Treatment
β WHO-recommended SAFE strategy:
β‘οΈ Surgery
β‘οΈ Antibiotics (especially azithromycin and tetracycline)
β‘οΈ Facial cleanliness
β‘οΈ Environmental improvement
π Key Features
β It is a Neglected Tropical Disease (NTD).
β In 2024, India received a Certificate of Elimination of Trachoma from the World Health Organization at the 78th World Health Assembly in Geneva.
β India became the third country in the WHO South-East Asia Region after Nepal and Myanmar to eliminate trachoma.
β Earlier, India had eliminated Guinea Worm Disease in 2000 and Yaws in 2016.
#GS3
#prelims
#science_technology
#science_and_technology
Join https://t.me/PIB_UPSC
https://t.me/upsc_science_and_technology
β€9