In 2022, researchers delivered world’s first gene therapy made using ‘base-editing’ 🧬 to a 13-year-old girl with ‘incurable’ T-Cell leukaemia. Now a further 8 children 👶 and 2 adults 👩🦳 have undergone treatment. 82% achieved very deep remissions. 63% remain disease-free ✨ 3 years later and off treatment.
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#GeneTherapy #BaseEditing #CancerResearch #TCellLeukaemia #MedicalBreakthroughs
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#GeneTherapy #BaseEditing #CancerResearch #TCellLeukaemia #MedicalBreakthroughs
GOSH Hospital site
‘Ready-made’ T-cell gene therapy tackles ‘incurable’ T-Cell leukaemia
A groundbreaking new treatment using gene-edited immune cells, developed by scientists at Great Ormond Street Hospital (GOSH) and University College London (UCL), has shown promising results in helping children and adults fight a rare and aggressive form…
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Gene edits known as base editing could solve obstacles to treating solid tumor cancers, such as lung, breast and kidney cancers, with CAR-T cell therapy, researchers find.
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#BaseEditing #CAR-TcellTherapy #SolidTumorCancers
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#BaseEditing #CAR-TcellTherapy #SolidTumorCancers
Northeastern Global News
Designing a better treatment for solid tumor cancers that works ‘off-the-shelf’
New research shows how to remove obstacles to solid tumor cancer treatments with genetic engineering.
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First use of precision editing to study human embryo development reveals role of master gene: « Scientists have, for the first time, used an extremely precise genome editing technique called base editing to study gene function in human embryos. »
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#GenomeEditing #EmbryoDevelopment #BaseEditing
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#GenomeEditing #EmbryoDevelopment #BaseEditing
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