A classic psychedelic, similar to LSD, psilocybin and mescalin, was found to activate a cell type in the brain that silences other neighboring neurons, a result that provides insight into how such drugs reduce anxiety, according to a new study in mice and rats.
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#Psychedelics #LSD #Psilocybin #Mescaline #AnxietyReduction
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#Psychedelics #LSD #Psilocybin #Mescaline #AnxietyReduction
Cornell University
Psychedelics excite cells in hippocampus to reduce anxiety
A classic psychedelic was found to activate a cell type in the brain of mice and rats that silences other neighboring neurons, providing insight into how such drugs reduce anxiety.
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Science News
One of the oldest psychedelics has almost never been studied with modern imaging because of its Schedule 1 status. New research in awake rats finds mescaline works through a brain region that LSD and psilocybin largely leave alone. Read Full Article #M…
🌵 New research from Northeastern University uses modern brain imaging to study mescaline, an ancient psychedelic derived from cacti. The study, published in Neuroscience Bulletin, suggests mescaline may contribute to hallucinations and sensory perception changes similar to those in some psychiatric conditions.
🧠 Researchers, including doctoral student Noah Cavallaro and Professor Craig Ferris, are using MRI machines to examine rodent brains after administering psychedelics. Their mescaline study found a paradoxical effect on the cerebellum, a brain region acting as a "gatekeeper" for sensory information.
🔬 Mescaline appears to "shut down" the cerebellum internally while increasing its communication with other brain areas, a phenomenon termed "hyperconnectivity." This unique dampening effect on the cerebellum suggests it could be key to the drug's hallucinatory effects, similar to patterns seen in patients experiencing their first schizophrenic episode.
#PsychedelicResearch #Neuroscience #Mescaline
🧠 Researchers, including doctoral student Noah Cavallaro and Professor Craig Ferris, are using MRI machines to examine rodent brains after administering psychedelics. Their mescaline study found a paradoxical effect on the cerebellum, a brain region acting as a "gatekeeper" for sensory information.
🔬 Mescaline appears to "shut down" the cerebellum internally while increasing its communication with other brain areas, a phenomenon termed "hyperconnectivity." This unique dampening effect on the cerebellum suggests it could be key to the drug's hallucinatory effects, similar to patterns seen in patients experiencing their first schizophrenic episode.
#PsychedelicResearch #Neuroscience #Mescaline