LSD reshapes the brain’s response to pain, neuroimaging study finds

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#LSD #Neuroimaging #BrainResearch #PainManagement #MentalHealth

A classic psychedelic, similar to LSD, psilocybin and mescalin, was found to activate a cell type in the brain that silences other neighboring neurons, a result that provides insight into how such drugs reduce anxiety, according to a new study in mice and rats.

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#Psychedelics #LSD #Psilocybin #Mescaline #AnxietyReduction

Systematic review and network meta-analysis finds psychedelics, especially psilocybin and LSD, showed promising effects on depression and anxiety in people with terminal illnesses.

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#Psychedelics #Psilocybin #LSD #MentalHealth #TerminalIllness

LSD flattens the hierarchy of directed information flow in fast whole-brain dynamics

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#LSD #BrainDynamics #Neuroscience #Consciousness #InformationFlow

By end of 6 week trial, both microdose LSD (20 micrograms) and placebo groups showed significant reductions in ADHD symptoms. Those who believed they took LSD reported greater symptom improvement, regardless of what they actually received. This suggests expectations may have played a large role.

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#ADHD #Microdosing #LSD #PlaceboEffect #MentalHealth

Student Finds the Psychedelic Fungus 🍄 in the Morning Glory 🌼 plant the Inventor of LSD 💊 Spent His Life Searching For | The discovery could reshape how we study psychedelic compounds in nature 🌱 and medicine 🩺.

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#PsychedelicResearch #MorningGlory #LSD #FungusDiscovery #PsychedelicsInMedicine

A single dose of LSD seems to reduce anxiety 🌈💊✨

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#LSD #MentalHealth #AnxietyRelief #PsychedelicResearch #Mindfulness

🧠 A new study in the Journal of Psychopharmacology suggests low doses of LSD (26 micrograms) can enhance how the brain processes emotional rewards in individuals with mild depression, leading to improved mood that lasts for days.

⚡ Researchers used electroencephalography (EEG) to measure electrical brain activity, finding that LSD temporarily normalized the blunted emotional response to negative feedback often seen in depression.

😊 Participants who showed the strongest increase in electrical response to losing money also reported the highest increases in positive mood, with this effect lingering 48 hours later.

#LSD #Microdosing #Neuroscience

LSD microdosing linked to acute mood improvements in adults with depression. In a small pilot study, participants taking low, precise doses reported feeling more energetic, creative, and connected on days they took the drug.

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#LSD #Microdosing #MentalHealthResearch

🍄 Microdosing LSD may temporarily boost mood, energy, and creativity in individuals with major depressive disorder, according to a pilot study published in Progress in Neuropsychopharmacology & Biological Psychiatry.

📈 Participants took precise, low doses (4-20 micrograms) twice weekly for eight weeks, adjusting their intake based on daily self-reported effects via a smartphone app.

📊 While daily mood questionnaires showed limited significant changes, a formal clinical interview at the trial's end indicated a 60% average drop in depression severity.

🔬 Blood tests revealed drug peak concentrations occurred around an hour after administration, aligning with reported psychological effects.

#Microdosing #LSD #Depression

✨ Specialized psychotherapy combined with LSD or psilocybin showed significant reductions in severe depression and anxiety within a standard hospital care program.

✨ A Swiss study analyzed data from adults with treatment-resistant depression/anxiety who received either 100mcg of LSD or 25mg of psilocybin between May 2024 and October 2025, observing robust symptom relief.

✨ Patients reported large reductions in rumination and catastrophizing, and increased positive reappraisal after therapy. Both substances were well-tolerated with mild, temporary side effects.

#PsychedelicTherapy #MentalHealth #LSD

LSD could improve motor learning the next day in healthy people

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#LSD #MotorLearning #Neuroscience

LSD helps the immune system fight bowel cancer

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#LSD #Immunotherapy #CancerResearch