About 1 in 8 US adults has tried or uses GLP-1 medication with 1 in 4 of those for weight loss but muscle loss can account for up to 40% of total weight loss. Scientists discover molecule that reverses muscle loss in mice, suggest that adding drug to boost this molecule may help prevent muscle loss.
Read Full Article
#GLP1WeightLoss #MuscleHealth #ObesityResearch #WeightManagement #HealthInnovation
Read Full Article
#GLP1WeightLoss #MuscleHealth #ObesityResearch #WeightManagement #HealthInnovation
Salk Institute for Biological Studies
Boosting this molecule could help retain muscle while losing fat - Salk Institute for Biological Studies
LA JOLLA—About one in eight adults in the United States has tried or currently uses a GLP-1 medication, and a quarter of those users cite weight loss as their main goal. But weight loss doesn’t discriminate between fat and muscle. Patients using GLP-1 drugs…
👍1🔥1
Possible New Therapeutic Approach for Aging and Degenerative Muscle Disorders. Researchers discovered a potential therapeutic target in muscular disorders by identifying a previously unrecognized role of a protein called Fn14 in regulating satellite cell (muscle stem cell) stability and function.
Read Full Article
#AgingResearch #MuscleHealth #TherapeuticInnovation #StemCellTherapy #DegenerativeDiseases
Read Full Article
#AgingResearch #MuscleHealth #TherapeuticInnovation #StemCellTherapy #DegenerativeDiseases
uh.edu
University of Houston Pharmacy Team Discovers Target to Repair Injured Muscles
A team at the University of Houston College of Pharmacy has discovered a possible therapeutic approach to repair injured muscles either from aging or degenerative muscle disorders.
Scientists have found a new cause for muscle loss in cancer. Tumors destroy blood vessels in muscles 🦠💪, this could lead to new treatments for cachexia.
Read Full Article
#MuscleHealth #CachexiaResearch #CancerAwareness #MedicalBreakthrough #TumorEffects
Read Full Article
#MuscleHealth #CachexiaResearch #CancerAwareness #MedicalBreakthrough #TumorEffects
Nature
Skeletal muscle endothelial dysfunction through the activin A–PGC1α axis drives progression of cancer cachexia
Nature Cancer - Using multiple in vivo mouse models, Rehman and colleagues report that tumor-induced impairments in the muscle vasculature mediated by circulating activin A contribute to cachexia...
People who consume ultra-processed foods have worse muscle health: a diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of calorie or fat intake, physical activity or sociodemographic factors
Read Full Article
#UltraProcessedFoods #MuscleHealth #NutritionScience
Read Full Article
#UltraProcessedFoods #MuscleHealth #NutritionScience
www.rsna.org
People Who Consume Ultra-Processed Foods Have Worse Muscle Health
MRI study published links high ultra processed food intake to increased thigh muscle fat, potentially raising knee osteoarthritis risk.
Science News
People who consume ultra-processed foods have worse muscle health: a diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of calorie or fat intake, physical activity or sociodemographic factors…
• 🦵 A study published in Radiology found that diets high in ultra-processed foods are linked to more fat within thigh muscles, a factor associated with knee osteoarthritis.
• 🍔 Researchers analyzed data from 615 individuals (average age 60, BMI 27) and discovered that higher consumption of ultra-processed foods correlated with increased intramuscular fat, independent of calorie intake or activity levels.
• 💡 The study, led by Zehra Akkaya, MD, from the University of California, San Francisco, suggests that improving diet quality by reducing ultra-processed foods may be crucial for muscle health and managing knee osteoarthritis, beyond just weight loss.
#UltraProcessedFoods #MuscleHealth #Osteoarthritis
• 🍔 Researchers analyzed data from 615 individuals (average age 60, BMI 27) and discovered that higher consumption of ultra-processed foods correlated with increased intramuscular fat, independent of calorie intake or activity levels.
• 💡 The study, led by Zehra Akkaya, MD, from the University of California, San Francisco, suggests that improving diet quality by reducing ultra-processed foods may be crucial for muscle health and managing knee osteoarthritis, beyond just weight loss.
#UltraProcessedFoods #MuscleHealth #Osteoarthritis
Science News
An experimental antibody may help people on GLP-1 meds preserve muscle mass Read Full Article #GLP1 #MuscleMass #AntibodyTherapy
🔬 A new experimental antibody, apitegromab, showed promise in a study published June 8 in Nature Medicine, helping patients taking GLP-1 weight loss drugs retain lean body mass.
💪 In a trial of 102 overweight or obese individuals, those who received apitegromab alongside tirzepatide lost half as much lean mass compared to those taking only tirzepatide, though both groups lost similar amounts of overall weight.
🤔 While the antibody helped preserve lean mass, leading to minor improvements in grip and leg strength, scientists are still investigating the long-term health benefits and if this approach will benefit a wider population beyond GLP-1 users.
#GLP1 #WeightLoss #MuscleHealth
💪 In a trial of 102 overweight or obese individuals, those who received apitegromab alongside tirzepatide lost half as much lean mass compared to those taking only tirzepatide, though both groups lost similar amounts of overall weight.
🤔 While the antibody helped preserve lean mass, leading to minor improvements in grip and leg strength, scientists are still investigating the long-term health benefits and if this approach will benefit a wider population beyond GLP-1 users.
#GLP1 #WeightLoss #MuscleHealth
👍1
Science News
A naturally occurring molecule released during exercise may hold the key to strengthening muscles without physical activity. In experiments, mice given BAIBA developed larger muscles, improved muscle function, greater fatigue resistance and better exercise…
💪 A naturally occurring molecule, L-BAIBA, released during exercise, shows promise in strengthening muscles and improving their resilience and efficiency.
🔬 Experiments in mice demonstrated that BAIBA administration led to larger muscles, better function, increased fatigue resistance, and improved exercise performance.
📈 BAIBA also appears to protect against muscle weakness in mouse models of obesity and type 2 diabetes, conditions often linked to reduced mobility.
🔬 The study, published in Nature Communications on August 18, 2026, identifies L-BAIBA as the key form responsible for many muscle-strengthening effects.
#ExerciseScience #MuscleHealth #Biotechnology
🔬 Experiments in mice demonstrated that BAIBA administration led to larger muscles, better function, increased fatigue resistance, and improved exercise performance.
📈 BAIBA also appears to protect against muscle weakness in mouse models of obesity and type 2 diabetes, conditions often linked to reduced mobility.
🔬 The study, published in Nature Communications on August 18, 2026, identifies L-BAIBA as the key form responsible for many muscle-strengthening effects.
#ExerciseScience #MuscleHealth #Biotechnology
🤡1💊1
Science News
Researchers analysed more than 80 studies examining the links between body weight, body fat, muscle health and dementia, finding people with sarcopenia – the loss of muscle mass and strength – had a 42 per cent higher risk of dementia. Read Full Article …
💪 Losing muscle mass (sarcopenia) is linked to a 42% higher risk of dementia, according to Curtin University research.
⚖️ Obesity in middle age (before 65) showed a 9% increased dementia risk, but obesity in those 65+ was linked to a 17% lower risk.
🧠 The study emphasizes that body weight alone isn't the whole story for dementia risk; maintaining muscle strength and function is crucial throughout life.
#DementiaRisk #MuscleHealth #AgingWell
⚖️ Obesity in middle age (before 65) showed a 9% increased dementia risk, but obesity in those 65+ was linked to a 17% lower risk.
🧠 The study emphasizes that body weight alone isn't the whole story for dementia risk; maintaining muscle strength and function is crucial throughout life.
#DementiaRisk #MuscleHealth #AgingWell