Scientists find the biological footprint of social anxiety may reside partially in the gut 🦠🧠 | Findings suggest that specific alterations in the gut-brain axis could contribute to the pathology of social anxiety during adolescence. 🌱💭

Read Full Article

#SocialAnxiety #GutHealth #GutBrainAxis #AdolescentMentalHealth #ScientificResearch

Ingested 🧫 micro and nanoplastics 🧬 may promote neurodegeneration 🧠 by disrupting the microbiota–gut–brain axis 🧬 and increasing systemic inflammation 🔥, oxidative stress ⚡, and epigenetic dysregulation 🧬, a review 📚 suggests

Read Full Article

#microplastics #gutbrainaxis #neurodegeneration #inflammation #epigenetics

Undigested fruit sugar is linked to increased anxiety and inflammation: The research suggests that unabsorbed fructose alters the community of bacteria in the digestive tract, which then triggers immune responses that can affect the brain. Study was done using healthy male humans and mouse models.

Read Full Article

#FructoseIntolerance #GutBrainAxis #MicrobiomeHealth

Memory loss is fuelled by gut microbes in ageing mice. If confirmed in people, the finding might lead to gut-targeted therapies that could reverse cognitive decline. Researchers determined that the bacterium interferes with signalling along sensory nerves that connect to the brain.

Read Full Article

#GutBrainAxis #CognitiveAging #MicrobiomeTherapy

🦠 Live gut bacteria can travel directly to the brain through the vagus nerve when the intestinal barrier is weakened. This discovery, published in PLOS Biology, may explain how digestive health impacts neurological conditions like Alzheimer's and autism.

🔬 Researchers used a high-fat diet in mice to induce a "leaky gut." They found specific gut bacteria in the brain, genetically matched to those in the intestines, and confirmed the vagus nerve as the transit route.

🧠 In mouse models of Alzheimer's, Parkinson's, and autism, weakened intestinal linings were observed, allowing gut bacteria to reach the brain. This bacterial presence in the brain was reversible when the gut lining healed.

#GutBrainAxis #Neuroscience #HealthTech

🦠 Gut bacteria can directly enter the brain through the vagus nerve when the intestinal barrier weakens.

🔬 Research using mice showed that a high-fat diet caused intestinal leakage, allowing gut bacteria to travel to the brain via the vagus nerve, bypassing the bloodstream.

🧠 This discovery offers a new explanation for how digestive health may influence neurological conditions like Alzheimer's and autism, suggesting the gut could be a new target for therapies.

#GutBrainAxis #Neurology #HealthTech

Live bacteria from the gut can travel directly into the brain when the intestinal barrier is weakened with a high fat diet in mice. This discovery offers a potential new explanation for how digestive health influences neurological conditions like Alzheimer’s disease and autism.

Read Full Article

#GutBrainAxis #Dysbiosis #NeurologicalHealth

🦠 Live gut bacteria can directly enter the brain through a weakened intestinal barrier, potentially explaining links between digestive health and neurological conditions like Alzheimer's and autism.

🧠 Researchers discovered this pathway involves the vagus nerve, bypassing the bloodstream. Mice fed a high-fat diet showed gut bacteria in their brains, which decreased after the vagus nerve was surgically severed.

🔬 Experiments using genetically modified bacteria confirmed their origin in the gut and transit to the brain via the vagus nerve. This transfer was reversible once the gut lining healed.

💡 Models mimicking Alzheimer's, Parkinson's, and autism showed gut bacteria in the brain even on normal diets, suggesting a leaky gut may be a common factor in these conditions.

#GutBrainAxis #Neuroscience #HealthTech

"Scientists just discovered that a high fat diet can cause gut bacteria to enter the brain".Live bacteria from the digestive system can travel directly into the brain when the intestinal barrier is weakened.

Read Full Article

#GutBrainAxis #DietAndMicrobiome #BloodBrainBarrier

🦠 Live bacteria can travel directly from the gut to the brain via the vagus nerve when the intestinal barrier weakens.

🔬 Research published in PLOS Biology used mice on a high-fat diet, revealing bacteria like Staphylococcus migrated from intestines to the brain, bypassing the bloodstream.

🧠 This pathway might explain how digestive health influences neurological conditions like Alzheimer's and autism, especially in mouse models of these diseases.

#GutBrainAxis #Neuroscience #Microbiome

Glyphosate: A common weedkiller may induce anxiety by disrupting gut bacteria. Researchers observed that rats drinking the chemical developed hypervigilance toward harmless objects and sounds. This altered behavior was accompanied by abnormal changes in a specific dread-inducing region of the brain.

Read Full Article

#Glyphosate #GutBrainAxis #AnimalStudy

New review proposes a gut-brain-immune framework for chronic constipation, linking microbiota, barrier function, and the enteric nervous system

Read Full Article

#GutBrainAxis #Microbiome #ConstipationResearch

The stomach helps the brain form memories: signals traveling from the gut through the vagus nerve can also help to form memories, with high-fat and high-sugar foods triggering the strongest memory-related brain activity in rats, but chronic exposure to these items worsens memory formation over time

Read Full Article

#GutBrainAxis #MemoryFormation #VagusNerve

Gut bacteria linked to key brain chemicals in first-of-its-kind human study. The relationship between the gut microbiome and brain chemistry was not uniform across the brain. Instead, different microbial pathways were associated with GABA, glutamate and E/I balance in different brain regions.

Read Full Article

#GutBrainAxis #Microbiome #BrainChemistry

From gut to brain: data-driven evidence suggests causal contribution of gut-microbiota to major depressive disorder in humans. The study found evidence for gut microbes Eggerthella and Hungatella as potential causal contributors to MDD.

Read Full Article

#GutBrainAxis #Microbiome #DepressionResearchers

Intestinal infections cause antigen-specific CD4+ T cells to migrate from the gut and establish long-lived memory in the brain and meninges, a mechanism the authors link to anxiety and depression in inflammatory bowel disease

Read Full Article

#Immunology #GutBrainAxis #CD4Tcells

🧠 A study in male mice found both too much and too little salt can harm cognitive function. High salt causes inflammation and memory loss, while low salt starves the gut microbiome, impacting brain function.

🔬 Researchers from Zhejiang University used "microbiome humanization" in mice to study the effects of normal, low, and high salt diets over 14 weeks.

🧠 Both low and high salt diets impaired short-term and long-term memory in mice. High salt led to the worst deficits, plus anxiety and increased thirst. Low salt caused memory issues without these extra symptoms.

🔬 The study observed that high salt increased inflammatory bacteria and fats, while low salt reduced beneficial microbes and crucial metabolic signals for the brain, impacting neuronal connections.

#GutBrainAxis #DietaryImpact #Neuroscience

New research shows that the gut bacterial metabolite imidazole propionate is strongly linked to accelerated cognitive decline and an increased risk of Alzheimer's disease by promoting brain inflammation, plaque buildup, and damage to the blood-brain barrier.

Read Full Article

#Alzheimer's #GutBrainAxis #BrainInflammation

Creatine, the cheap gym supplement, protected the brain from gut inflammation in rats with chronic colitis. It blocked brain inflammation, neuron loss and faulty electrical signals in the brain's memory center (hippocampus). Male rats were hit much harder than females. It's not yet tested in humans.

Read Full Article

#Creatine #BrainHealth #GutBrainAxis

🧠 New research in Brain, Behavior, and Immunity shows creatine supplementation protected rat brains from damage caused by chronic colitis. The study found creatine prevented brain inflammation, nerve cell damage, and disrupted electrical activity in the hippocampus.

🔬 The damage from colitis was more severe in male rats, which experienced physical damage to hippocampal neurons and altered electrical properties. Female rats showed less physical impact but had increased inflammatory molecules.

⚡ Creatine supplementation largely prevented these issues in both sexes, restoring hippocampal creatine levels and stopping the activation of immune cells in the brain. It maintained the structural health of neurons and their electrical properties in males.

⚠️ Researchers caution that these findings are from rat studies and have not been tested in humans. Creatine is not presented as a treatment for inflammatory bowel disease, but the results suggest a potential protective role for the brain.

#GutBrainAxis #Creatine #Neuroscience