Knocking out a gene doesn’t always rob the target cells of their mRNA and protein. Sometimes neighboring cells can provide these basic outputs to, in effect, compensate for the disabled gene. A recent mouse study pinpoints how, at least in fat tissue. 🧬🐭💉
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#GeneKnockout #CellCompensation #mRNA #ProteinSynthesis #MouseStudy
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#GeneKnockout #CellCompensation #mRNA #ProteinSynthesis #MouseStudy
PNAS
In fat tissue, neighbor cells lend a hand when critical genes stop working
Fat cells (in green) can receive mRNA and proteins from neighboring cells. Image Credit: Daeseok Kim, Touchstone Diabetes Center, UT Southwestern Medical Center.
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A new study from Stanford University shows a direct link between mRNA COVID-19 vaccines and myocarditis 💉❤️, as well as explaining the mechanism of action 🔍.
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#StanfordStudy #COVID19Vaccines #MyocarditisResearch #mRNA #HealthScience
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#StanfordStudy #COVID19Vaccines #MyocarditisResearch #mRNA #HealthScience
News Center
Stanford Medicine study shows why mRNA COVID-19 vaccine can cause myocarditis
COVID-19 — and, less frequently, the mRNA-based COVID-19 vaccine — can cause inflamed heart tissue in some people. A new study implicates a pair of substances secreted by immune cells and proposes a strategy to mitigate the vaccine effect.
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FDA refuses to review Moderna’s mRNA flu vaccine
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#FDA #Moderna #mRNA #FluVaccine #News
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#FDA #Moderna #mRNA #FluVaccine #News
Moderna’s mRNA flu vaccine more effective than standard shot in late-stage trial
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# Moderna #mRNA #FluVaccine
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# Moderna #mRNA #FluVaccine
NBC News
Moderna’s mRNA flu vaccine more effective than standard shot in late-stage trial
An mRNA-based flu shot could make a huge difference in flu prevention, allowing scientists to pick a better strain match.
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Science News
Moderna’s mRNA flu vaccine more effective than standard shot in late-stage trial Read Full Article # Moderna #mRNA #FluVaccine
🔬 Moderna's mRNA flu vaccine showed ~27% better protection against illness than standard flu shots in a Phase 3 trial of over 40,000 adults aged 50+, with 2% falling ill vs. 2.8% in the standard shot group.
⏱️ mRNA technology allows for quicker updates to flu vaccines, potentially matching circulating strains better than traditional shots, which take months to produce and risk being mismatched.
🧐 The FDA previously rejected Moderna's initial submission for this mRNA flu vaccine. The new results, published in the New England Journal of Medicine, could boost its chances for approval, with a decision expected by Aug. 5.
#FluVaccine #mRNA #PublicHealth
⏱️ mRNA technology allows for quicker updates to flu vaccines, potentially matching circulating strains better than traditional shots, which take months to produce and risk being mismatched.
🧐 The FDA previously rejected Moderna's initial submission for this mRNA flu vaccine. The new results, published in the New England Journal of Medicine, could boost its chances for approval, with a decision expected by Aug. 5.
#FluVaccine #mRNA #PublicHealth
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mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models
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#mRNA vaccines #TB vaccine #immunogenicity
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#mRNA vaccines #TB vaccine #immunogenicity
Nature
mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models
Nature Immunology - Here the authors characterize mRNA-based tuberculosis vaccine candidates BNT164a1 and BNT164b1 and show that they are immunogenic, well tolerated and efficacious in preclinical...
Science News
Billions of doses later: Global review confirms mRNA vaccines are safe, effective and full of promise. Comprehensive review brings together global evidence to strengthen public trust and counter misinformation as mRNA vaccines expand to prevent and treat more…
✅ A comprehensive global review published in The Lancet, led by the University of British Columbia, confirms that mRNA vaccines, administered billions of times worldwide, are safe and highly effective against infectious diseases like COVID-19.
✅ The review highlights that while rare side effects like myocarditis can occur, serious adverse events are consistently outweighed by the protection against severe illness, hospitalization, and death.
✅ Beyond infectious diseases, the research indicates significant promise for mRNA technology in preventing and treating other conditions, including influenza, RSV, cancer, and autoimmune disorders.
✅ Researchers aim to build public trust and counter misinformation by providing clear, evidence-based information, emphasizing that mRNA vaccines do not alter DNA and are quickly cleared from the body.
#MRNA #VaccineSafety #PublicHealth
✅ The review highlights that while rare side effects like myocarditis can occur, serious adverse events are consistently outweighed by the protection against severe illness, hospitalization, and death.
✅ Beyond infectious diseases, the research indicates significant promise for mRNA technology in preventing and treating other conditions, including influenza, RSV, cancer, and autoimmune disorders.
✅ Researchers aim to build public trust and counter misinformation by providing clear, evidence-based information, emphasizing that mRNA vaccines do not alter DNA and are quickly cleared from the body.
#MRNA #VaccineSafety #PublicHealth
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mRNA immunotherapy eliminates pancreatic tumors in mice: Approximately 50% of mice with pancreatic cancer treated with the mRNA immunotherapeutic cocktail saw complete tumor responses and more impressively, remained disease free for a year, even after treatment had been stopped.
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#mRNAImmunotherapy #PancreaticCancer #CancerResearch breakthroughs should be one word per hashtag; but instruction says format with # and separate with spaces. Ensure exactly three hashtags, no extra text. Use common tags: #mRNA, #Immunotherapy, #PancreaticCancer? They want high-traffic. Use #mRNA #Immunotherapy #PancreaticCancer? But they require hashtags with #. Should be readable: #mRNAImmunotherapy #PancreaticCancer #CancerResearch. But 3. Let's pick: #mRNAImmunotherapy #PancreaticCancer #CancerResearch
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#mRNAImmunotherapy #PancreaticCancer #CancerResearch breakthroughs should be one word per hashtag; but instruction says format with # and separate with spaces. Ensure exactly three hashtags, no extra text. Use common tags: #mRNA, #Immunotherapy, #PancreaticCancer? They want high-traffic. Use #mRNA #Immunotherapy #PancreaticCancer? But they require hashtags with #. Should be readable: #mRNAImmunotherapy #PancreaticCancer #CancerResearch. But 3. Let's pick: #mRNAImmunotherapy #PancreaticCancer #CancerResearch
UMass Chan Medical School
mRNA immunotherapy developed by UMass Chan scientists eliminates pancreatic tumors in mice
Novel mRNA treatment developed at UMass Chan Medical School eliminates pancreatic cancer tumors in 50 percent of treated mice.