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Knocking out a gene doesn’t always rob the target cells of their mRNA and protein. Sometimes neighboring cells can provide these basic outputs to, in effect, compensate for the disabled gene. A recent mouse study pinpoints how, at least in fat tissue. 🧬🐭💉

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#GeneKnockout #CellCompensation #mRNA #ProteinSynthesis #MouseStudy
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FDA refuses to review Moderna’s mRNA flu vaccine

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#FDA #Moderna #mRNA #FluVaccine #News
Science News
Moderna’s mRNA flu vaccine more effective than standard shot in late-stage trial Read Full Article # Moderna #mRNA #FluVaccine
🔬 Moderna's mRNA flu vaccine showed ~27% better protection against illness than standard flu shots in a Phase 3 trial of over 40,000 adults aged 50+, with 2% falling ill vs. 2.8% in the standard shot group.

⏱️ mRNA technology allows for quicker updates to flu vaccines, potentially matching circulating strains better than traditional shots, which take months to produce and risk being mismatched.

🧐 The FDA previously rejected Moderna's initial submission for this mRNA flu vaccine. The new results, published in the New England Journal of Medicine, could boost its chances for approval, with a decision expected by Aug. 5.

#FluVaccine #mRNA #PublicHealth
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Science News
Billions of doses later: Global review confirms mRNA vaccines are safe, effective and full of promise. Comprehensive review brings together global evidence to strengthen public trust and counter misinformation as mRNA vaccines expand to prevent and treat more…
✅ A comprehensive global review published in The Lancet, led by the University of British Columbia, confirms that mRNA vaccines, administered billions of times worldwide, are safe and highly effective against infectious diseases like COVID-19.

✅ The review highlights that while rare side effects like myocarditis can occur, serious adverse events are consistently outweighed by the protection against severe illness, hospitalization, and death.

✅ Beyond infectious diseases, the research indicates significant promise for mRNA technology in preventing and treating other conditions, including influenza, RSV, cancer, and autoimmune disorders.

✅ Researchers aim to build public trust and counter misinformation by providing clear, evidence-based information, emphasizing that mRNA vaccines do not alter DNA and are quickly cleared from the body.

#MRNA #VaccineSafety #PublicHealth
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mRNA immunotherapy eliminates pancreatic tumors in mice: Approximately 50% of mice with pancreatic cancer treated with the mRNA immunotherapeutic cocktail saw complete tumor responses and more impressively, remained disease free for a year, even after treatment had been stopped.

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#mRNAImmunotherapy #PancreaticCancer #CancerResearch breakthroughs should be one word per hashtag; but instruction says format with # and separate with spaces. Ensure exactly three hashtags, no extra text. Use common tags: #mRNA, #Immunotherapy, #PancreaticCancer? They want high-traffic. Use #mRNA #Immunotherapy #PancreaticCancer? But they require hashtags with #. Should be readable: #mRNAImmunotherapy #PancreaticCancer #CancerResearch. But 3. Let's pick: #mRNAImmunotherapy #PancreaticCancer #CancerResearch