Lower levels of testosterone, combined with higher levels of a protein called neurofilament light chain, significantly increase the risk of cognitive decline in older men, finds a new study from China in Alzheimer’s & Dementia.

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#Testosterone #NeurofilamentLightChain #CognitiveDecline #Alzheimers #HealthResearch

Testosterone is protective against severe Covid-19, suggests a new study. The effect may arise because the hormone reduces inflammation in the lungs and other organs. The findings have public health and treatment implications.

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#testosterone #covid19 #inflammation #publichealth #treatmentimplications

Testosterone spikes linked to stronger political opinions in men. Both hormone levels and opinions were stronger at 9:00 AM than at 12:00 PM or 3:00 PM. Younger men also had higher testosterone levels than older participants.

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#Testosterone #PoliticalOpinions #MenHealth #HormoneLevels #YoungerMen

Testosterone heightens men’s sensitivity to social feedback and reshapes self-esteem. When men in the testosterone group received positive feedback, their self-esteem increased more than it did in the placebo group. But when they received negative feedback, their self-esteem dropped more sharply. 💪📈📉

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#Testosterone #SelfEsteem #SocialFeedback #MensHealth #Psychology

New study found that higher testosterone was linked to lower perceived stress in young men 💪, but only when cortisol levels were low 🌿. Conversely, high cortisol was linked to lower stress perception in those with low testosterone 😟.

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#Testosterone #Cortisol #StressPerception #YoungMen #HealthStudy

Men who were obese as children tended to have shorter penises as adults, finds new study from Vietnam. 📉👶➡️👨‍🦱📏 Penis size was not associated with men's current body mass index (BMI). Obesity is associated with declines in testosterone during puberty, and testosterone is important for penile development. 🧬📉

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#PenisSize #ChildhoodObesity #Testosterone #HealthStudy #MenHealth

Exposure of mice to PFAS 'forever chemicals' reduced testosterone levels and sperm production, and fathered embryos with 'aberrant gene expression' 🐭⚗️📉🧬

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#PFAS #ForeverChemicals #Testosterone #SpermHealth #GeneExpression

Testosterone in body odour linked to perceptions of social status: both male and female participants perceived men with higher levels of testosterone to be more dominant than men with lower testosterone levels 💪👃📈

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#Testosterone #BodyOdour #SocialStatus #Dominance #GenderPerception

‘Manosphere’ influencers pushing testosterone tests 🧪 are convincing healthy young men there is something wrong with them – monetising masculinity, ⚠️ pathologising normal male experiences and driving unnecessary, risky hormone use, study finds. 💰

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#manosphere #testosterone #masculinity #healthcommunication #misinformation

🔬 A meta-analysis of 52 studies, involving 17,340 participants, found virtually no overall link between testosterone levels and risk-taking behavior.

📊 A modest association was only observed in studies using specific lottery-based economic tasks to measure risk-taking; other methods, including impulsive games and self-reports, showed no connection.

⚖️ The lack of association between testosterone and risk-taking was consistent across both male and female participants.

📚 The findings, published in Neuroscience and Biobehavioral Reviews, challenge the idea that testosterone is a primary biological driver of human risk preferences, suggesting societal and psychological factors are more influential.

#Testosterone #RiskTaking #Neuroscience

🔬 UNIGE study on 94 Swiss conscripts (aged 18-23) shows cannabis use leads to a ~23% increase in testosterone in young men, specifically originating from the testes.

🔬 Researchers identified two new potential biomarkers for regular cannabis use: hydroxyprogesterone (11B-OHP4) and dihydroprogesterone (5B-DHP4).

🔬 Despite the testosterone increase, the study found no clear impact on male fertility or sperm quality, suggesting a complex relationship and potential compensatory responses by the body.

#CannabisResearch #Testosterone #MensHealth

🔬 A new study challenges the idea that testosterone makes men rely on gut feelings over deliberate thought. The research found a single dose of testosterone did not significantly alter decision-making, and surprisingly, might even lower confidence in cognitive performance.

🔬 In a large-scale, collaborative study of 1,000 men, researchers found no significant difference in test scores between those who received testosterone and those who received a placebo. Participants who received testosterone actually reported lower confidence in their performance.

🔬 The study, published in Psychological Science, involved an adversarial collaboration where scientists with opposing views worked together. This rigorous, double-blind, randomized, placebo-controlled experiment aimed to resolve conflicting previous findings.

🔬 While this study focused on short-term testosterone spikes in men, it did not examine long-term exposure or effects on women. Researchers noted that future studies should include female participants to explore potential differences.

#Testosterone #CognitiveScience #Psychology

🧠 Men with testosterone levels significantly higher or lower than average for their age group show an increased risk of depression. This finding, from a study of 133,733 men aged 40-70, suggests hormonal imbalances can signal mental health vulnerabilities, particularly in men around their early fifties.

📊 The study, published in the Journal of Affective Disorders, analyzed data from the UK Biobank over nearly 11 years. Researchers compared total and free testosterone levels to age-adjusted averages, finding low free testosterone was linked to about twice the risk of developing depression and a higher chance of experiencing both anxiety and depression simultaneously.

📈 The risk for mood disorders due to hormonal imbalances was strongest in middle-aged men. For example, men aged 50-54 with low free testosterone had roughly a fivefold increase in anxiety risk, while those aged 55-59 with low free testosterone saw more than triple the risk of depression.

#MensHealth #MentalHealth #Testosterone

Men with low or high testosterone may have higher risk of irregular heartbeat. Relationship between testosterone and atrial fibrillation (AF) appears to follow U-shaped pattern: men with low and with high testosterone both show higher risk of AF, while risk appears lowest in middle of normal range.

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#AtrialFibrillation #Testosterone #CardioHealth

❤️ Testosterone Levels & Heart Rhythm: New research published in the Journal of the Endocrine Society suggests both low and high testosterone levels may increase the risk of atrial fibrillation (AF). The study indicates the lowest AF risk is observed when testosterone levels are within the normal range.

🔬 Personalized Treatment Focus: The review advocates for individualized testosterone replacement therapy, recommending clinicians aim to restore levels to the middle of the normal range (approximately 350–550 ng/dL total testosterone) rather than the high end, with structured monitoring.

📈 U-Shaped Risk Pattern: Evidence suggests a U-shaped relationship between testosterone and AF risk. Men with testosterone levels at either extreme of the spectrum appear to have a higher risk, while those in the middle of the normal range face the lowest risk.

#Testosterone #HeartHealth #Endocrinology

✅ New research suggests deep belly fat (visceral fat) may be a more significant factor in lowering testosterone levels in men than chronological aging alone, particularly for those aged 20-59.

✅ A review of nearly 5,000 US men found visceral fat strongly linked to testosterone suppression, influencing hormone levels more than age within this group.

✅ Scientists Karl Friedl and Adam Potter suggest visceral fat, which wraps around organs, should be the "primary adiposity correlate of low testosterone in US men," potentially impacting hormone production through insulin resistance and inflammation.

#Testosterone #Health #MensHealth