Wider sample used data from across 29 countries and 5m people, with a quarter from non-European ancestries

Recent research found that the psychedelic drug DOI reduced heroin-seeking behavior in rats by lowering their motivation to obtain heroin. This effect was mediated through 5-HT2A receptors, suggesting DOI’s potential therapeutic role in opioid use disorder…

A new USC study suggests that gut imbalances in children with autism may create an imbalance of metabolites in the digestive system — ultimately disrupting neurotransmitter production and influencing behavioral symptoms.

Delta opioid receptor agonists improved social avoidance, depression, and anxiety-like symptoms induced by chronic social defeat stress within 14 days of chronic administration. Furthermore, the ther...

Nature Genetics - Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as...

The largest genetic study on anxiety disorders to date reveals new biological mechanisms behind anxiety. It can help to find new ways to develop more precise therapies.

Increased brain-age gap correlating with the severity of a psychotic experience found in young adults

Medical cannabis use was "the biggest factor in alleviating anxiety"

A double-blind trial suggests that microdosing the psychedelic drug LSD can reverse blunted neurological responses to emotional rewards, potentially offering targeted biological interventions for individuals struggling with mild to moderate depression.

A new study reveals that white blood cells in people with depression show abnormal activity in genes usually associated with brain connections. The findings highlight depression as a whole-body condition, potentially paving the way for future blood-based…

Background
Several lines of evidence suggest that vitamin B6 has potential as an antidepressant. It plays a crucial coenzyme role in the synthesis of the neurotransmitters serotonin, gamma-aminobuty...

A gene involved in regulating the body’s response to stress switches on more easily in the brains of people who live with schizophrenia, new research by University of Sydney experts finds.

When people stop taking antidepressants, a sudden wave of anxiety or depression can feel like a devastating setback. But new research suggests these emotional spikes are usually a temporary physical withdrawal reaction, rather than a true relapse.

A single dose of psilocybin eased depression within days in a small Swedish trial, outperforming an active placebo for more than three months on patients’ self-ratings. By one year, however, the placebo group had largely caught up.