Nature Communications - The neural mechanisms underlying the antidepressant effects of nitrous oxide remain poorly understood. This study reveals that specific activation of layer V pyramidal...

A new study suggests that people who have sex at least once a week are less likely to experience depression.

A massive South Korean study suggests that people who keep up regular exercise—or increase it—over several years are less likely to develop depression. The findings underscore the importance of physical activity patterns, not just single snapshots, in mental…

An eight-week intervention using bright light therapy led to measurable reductions in depressive symptoms and changes in neural connectivity in participants with subthreshold depression, according to a randomized controlled neuroimaging study published in…

A small pilot study found that a single 25 mg dose of psilocybin led to lasting reductions in depression symptoms among U.S. military veterans with treatment-resistant depression. Half were in remission after six months; 30% remained in remission at one year.

Study suggests well-formulated ketogenic diet is feasible add-on mental health therapy

A new study shows that a personalized, precise form of brain stimulation, HD-tDCS, can rapidly ease depression symptoms – and even reduce anxiety – offering a promising drug-free alternative with only mild side effects.

Researchers find that magic mushroom–assisted therapy may offer long-lasting relief for major depression.

A new study shows longer-term use of generic ketamine for severe depression is safe and effective, but researchers say access to the low-cost option remains limited by funding gaps.

In the most comprehensive investigation of the ketogenic diet’s mental health effects yet, researchers pooled 50 studies spanning six decades to see what we actually know about its influence on mood. The results are a mix of promising and "too early to say."

A new generation of rapid-acting treatments.